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The map label for this gene is pbuG [H]

Identifier: 218233002

GI number: 218233002

Start: 261380

End: 262705

Strand: Direct

Name: pbuG [H]

Synonym: BCB4264_A0302

Alternate gene names: 218233002

Gene position: 261380-262705 (Clockwise)

Preceding gene: 218231195

Following gene: 218232740

Centisome position: 4.82

GC content: 40.8

Gene sequence:

>1326_bases
ATGAAACGCTATTTTCAGTTTGATGAGCTCGGTACGAATTATAAGACTGAGTTCATAGCAGGGTTAACGACATTTCTATC
TATGGCTTACGTACTATTTGTCAATCCTGCTACGCTGTCGCTTGGAAATGTTAAAGGGTTACCAGCAGGTACAGGGATGG
ATCCAGGTGCAGTATTTGTTGCTACGGCATTAGCGGCAGCAATCGGTTCGTTAGTTATGGGTATTTTCGCGAAGTATCCA
ATTGCTTTAGCGCCAGGTATGGGAATTAACGCGTTCTTTGCTTATACAGCAGTGTTAACGATGGGTATTCCGTGGCAAAC
GGCCATTGCCGGAACATTAATGTCAGGTATTATCTTTATTATTCTTACTGCTTCAGGTATTCGTGAAAAAATCATTAATG
CAATTCCATCGGAGTTAAAGTTTGCAGTAGCAGCAGGTATCGGATTGTTCATTGCATTCCTTGGATTCCAAAATGCTGGA
ATTATCGTGAAAAATGATGCTGTTCTTGTTGGGTTGGGGGACTTAACAAAGGGTACAACGTTACTAGCAATCTTCGGGGT
TGTTACGACAATTATCTTCATGATTAAGAAAGTTAATGGTGCAGTATTTTACGGTATGATTCTTACAGCGATCTTAGGAG
TGGCAACAGGATTAATTGATACTCCGAAAGCTGTAGTAGGAGCAATACCGAGTCTAGAACCAACGTTCGGTGTGGCGTTA
ACGCACTTCGGAGATATTTTTACAGTTCAAATGGGGATTGTTATTATAACGTTCTTCTTTATCGATTTCTTTGATACAGC
AGGTACGCTTGTAGCGGTTGCGAATCAAGCTGGATTAATGAAGAACAATAAATTACCACGTGCAGGAAAAGCATTATTTG
CAGATGCGATTGCGACTGTAATTGGTGCAATCTTGGGTACATCAACAACAACGTCTTACATTGAATCGTCTGCAGGGGTA
GCAGCAGGAGGACGTTCTGGATTTACAGCAGTTGTAACAGCAGGATTCTTTTTACTGGCACTATTCTTCTCGCCATTACT
AAGTGTTGTAACGCCAGCTGTAACGGCGCCGGCTTTAATTATTGTAGGAATCTTGATGGTTTCTTCCTTAGGGGAAATTG
ATTGGAAGAAATTCGAGATTGCAGTGCCAGCATTCTTTACAATTATCTCTATGCCACTTACGTATAGTATCGCAACTGGG
ATTGCGATTGGATTTATCTTCTATCCGATTACAATGGTTGTGAGTGGTCGTCGTAAAGAGGTTCATCCGATTATGTATGT
TATGGGAGTTTTATTCGTACTATATTTCATCTACGTTCGTAAATAA

Upstream 100 bases:

>100_bases
CTTCCATGTATATATGCAATGGAAGCCTTTTTTATTTCTCGGGATAAAAGAGGGCTAGGGTGAAATACGGCGAGTAATCA
TATAACGGGGGAAACGTAGG

Downstream 100 bases:

>100_bases
AAGGGGTTTTTTAAAGGTCTAGACTTAAGGGGAGTCTAGACCTTTTTTGCGTCTTCAGAAAATCTTAAGGATTTCCGAGC
GTTTTTCTTCAGAAGTTTTC

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLVMGIFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEVHPIMYVMGVLFVLYFIYVRK

Sequences:

>Translated_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLVMGIFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEVHPIMYVMGVLFVLYFIYVRK
>Mature_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLVMGIFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEVHPIMYVMGVLFVLYFIYVRK

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=446, Percent_Identity=41.7040358744395, Blast_Score=334, Evalue=8e-93,
Organism=Escherichia coli, GI1790150, Length=440, Percent_Identity=41.1363636363636, Blast_Score=321, Evalue=7e-89,
Organism=Escherichia coli, GI1790499, Length=446, Percent_Identity=34.7533632286996, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI48994909, Length=431, Percent_Identity=33.1786542923434, Blast_Score=195, Evalue=6e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46308; Mature: 46308

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLVMGIFAKYPIALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFI
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGTT
HHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATV
HHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLVMGIFAKYPIALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFI
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGTT
HHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATV
HHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]