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The map label for this gene is inlA [H]

Identifier: 218232900

GI number: 218232900

Start: 1338639

End: 1340921

Strand: Direct

Name: inlA [H]

Synonym: BCB4264_A1382

Alternate gene names: 218232900

Gene position: 1338639-1340921 (Clockwise)

Preceding gene: 218234774

Following gene: 218231078

Centisome position: 24.7

GC content: 31.54

Gene sequence:

>2283_bases
TTGAAAAAAAATTATATGAAGGCGCTAGTAGTAGCGACAACATTAGCGATTCCATTTGCTACGTACTCTACTCCAGCATT
AGCGGCATTAAAAGTTGAAGCAAATCAATCGGTAGCAGCAGCGAGTGATCGCACGTATGATACTGAGATTAAAATATATA
AGGACCAAAAAGATGAGCCATCTATGGTTTCTCAATATATAAAAGATCCTAAAGTAACGATTGCAGCTGGCAAAAAAATT
GTCACTGTAACAATGCAAGATAGCGATTATTTTCAATATCTTAGAATAGAAGATAAAAACCAGCCTGGTGTATTTCATGA
TGTGAAGGTTTTGTCAGAAGATAAGAGGAAGAATGGAACGAAGGTAGTTCAATTTGAAATTGGCGAGTTTGAGAAGAAGC
ACAATATGCAAATGCATATACTTATTCCAGCTATTGGATATGATCACAAATATCAAGTTCAATTTGAAATTAAAGATCCA
ACTGTAGGTAACAAAGAAACAGAGAAACCAGATGATAACTCTAATTCAGGAAATACGGAAACGGATAATCCAGTTGATAA
TCAAAATATGATAACAGATAACAAATTAAGAGAGCTTGTTAATAAAAAAGTATTTAATAGAAAAGATTTAAATACACCAA
TTACGAAAGAAGATTTATTACAAGTAAAGGATTTGTTTTTAAATACAAATGAGATACTTGATTATAGTGCATTAAAATAT
ATGCCAAATTTAAAATCTTTAACAGTTGCGAATGCGAAGATAAAGGATCCGTCGTTCTTTGCGAACTTAAAGCAATTAAA
TCATTTAGCTTTGCGTGGTAATGAATTTGCAGATGTAATGCCACTTGTTAAGATGGATAATTTAGAATCCCTTGATTTAA
GTAATAATAAAATTACAAACGTTGCACCACTAACTGAAATGAAAAATGTAAAAAGTTTATTTCTATCAGGCAACCAAATA
GAAGATGTAACAGCATTAGCGAAAATGGAACAACTAGATTACTTGAATTTAGCAAATAATAAAATTACGAACGTTGCTCC
ATTAAGCAATTTGAAAAATGTAACATACTTAACTTTAGCAGGTAATCAAATTGAAGATATTAAACCGCTTTATACATTAC
CGTTAAAAGATTTAGTATTAACACGTAATAAAGTGAAAGATTTATCAGGCATTGATCAATTGAATCAATTACAAGAGCTA
TGGATAGGGAAAAATGAAATAACAGATGTTACTCCTCTAAGTAAGATGACACAGTTGAAAATTTTAAACTTACCCAACAA
CGAGTTAAAAGATATTACTCCATTATCAAGTTTAGTAAACTTACAAAAGCTTGATTTAGAAGCGAATTATATTTCAGACT
TATCACCAGTTAGTAATTTAAAAAAATTAGTATTTCTAAGTTTTGTTGCAAATGAAATCCGTGATGTCCGACCAGTTATA
GAACTAAGTAAGACGGCTTATATTAATGTCCAAAATCAAAAAGTATTTTTAGAGGAAACAGAAGTAAATAAAGAAGTAAA
AGTACCTATATATGAAAAAGATGGTGAGATTTCTACGAAAATCCGTCTGAAGAGCGATAATGGTACGTATAGTAATGGTG
TAGTGAAATGGAGTACACCAGGTGAGAAAGTATATGAATTTGGTGTGAAAGATCCATTCGCGGATACAGGAATCTTCTTT
ACAGGATCTGTTATTCAAAATGTAGTAGAAAGTAAAGACGGTAATACATCTAAAGAAGATGAGAAAACAGAAGTGGTAGA
ATTTAAAGATGTACCAAAGGGACATTGGTCAGAAGAAGCAATTAATTACTTAGCGAAAGAAAAATTATTTATAGGCTATG
GAAATGGTGAATTTGGATTTGGTGATAACATTACTCGTGGACAAGTAGCACTTCTAATACAAAGATATTTAAAATTAGAA
AATAATCTAGAACAAAAAACGGCATTTACAGATACGAAAGGAAATATGTATGAAACGGCTATTGATGCAGTGGTTCAAGC
TGGAATTATGACAGGCTATGGAAATGGTATGTTCCGTCCGGATGGAGTATTAACTCGATATGAAATGTCAGTAGTACTAC
AAAGAGTATTTCAGTTAAAAGAAAATGAAAATAGTGCAGAGAATTTTAAAGATGTACCAAATGGCCATTGGGCGAAAGGA
TATGTGAAAGCTTTAGTGGATAATAAAATATCAAAAGGCGACGGGGAAGGGAATTTTTTAGGAGATAATTTCGTAACACG
TGAACAATACGCACAGTTTTTGTATAATGCAATAAAGAAATAA

Upstream 100 bases:

>100_bases
ATTCTCATTGACAATGATAATGAGATTCATTATCATTTATTTGTGATTAATTGATAAATGTTATCAATTGTGAAAATTAT
ATATGATAGGGGATATTATT

Downstream 100 bases:

>100_bases
AGTGAAACTTTATTCAGTGGGGGTTTTGTTCATTCCCCACTGATTAGTAGCCCTCACCAATCGGGCTGCCCGTTAATGCG
GAATAAAAAATGAGGAAAAT

Product: putative internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MKKNYMKALVVATTLAIPFATYSTPALAALKVEANQSVAAASDRTYDTEIKIYKDQKDEPSMVSQYIKDPKVTIAAGKKI
VTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDP
TVGNKETEKPDDNSNSGNTETDNPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEDLLQVKDLFLNTNEILDYSALKY
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFADVMPLVKMDNLESLDLSNNKITNVAPLTEMKNVKSLFLSGNQI
EDVTALAKMEQLDYLNLANNKITNVAPLSNLKNVTYLTLAGNQIEDIKPLYTLPLKDLVLTRNKVKDLSGIDQLNQLQEL
WIGKNEITDVTPLSKMTQLKILNLPNNELKDITPLSSLVNLQKLDLEANYISDLSPVSNLKKLVFLSFVANEIRDVRPVI
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGEISTKIRLKSDNGTYSNGVVKWSTPGEKVYEFGVKDPFADTGIFF
TGSVIQNVVESKDGNTSKEDEKTEVVEFKDVPKGHWSEEAINYLAKEKLFIGYGNGEFGFGDNITRGQVALLIQRYLKLE
NNLEQKTAFTDTKGNMYETAIDAVVQAGIMTGYGNGMFRPDGVLTRYEMSVVLQRVFQLKENENSAENFKDVPNGHWAKG
YVKALVDNKISKGDGEGNFLGDNFVTREQYAQFLYNAIKK

Sequences:

>Translated_760_residues
MKKNYMKALVVATTLAIPFATYSTPALAALKVEANQSVAAASDRTYDTEIKIYKDQKDEPSMVSQYIKDPKVTIAAGKKI
VTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDP
TVGNKETEKPDDNSNSGNTETDNPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEDLLQVKDLFLNTNEILDYSALKY
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFADVMPLVKMDNLESLDLSNNKITNVAPLTEMKNVKSLFLSGNQI
EDVTALAKMEQLDYLNLANNKITNVAPLSNLKNVTYLTLAGNQIEDIKPLYTLPLKDLVLTRNKVKDLSGIDQLNQLQEL
WIGKNEITDVTPLSKMTQLKILNLPNNELKDITPLSSLVNLQKLDLEANYISDLSPVSNLKKLVFLSFVANEIRDVRPVI
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGEISTKIRLKSDNGTYSNGVVKWSTPGEKVYEFGVKDPFADTGIFF
TGSVIQNVVESKDGNTSKEDEKTEVVEFKDVPKGHWSEEAINYLAKEKLFIGYGNGEFGFGDNITRGQVALLIQRYLKLE
NNLEQKTAFTDTKGNMYETAIDAVVQAGIMTGYGNGMFRPDGVLTRYEMSVVLQRVFQLKENENSAENFKDVPNGHWAKG
YVKALVDNKISKGDGEGNFLGDNFVTREQYAQFLYNAIKK
>Mature_760_residues
MKKNYMKALVVATTLAIPFATYSTPALAALKVEANQSVAAASDRTYDTEIKIYKDQKDEPSMVSQYIKDPKVTIAAGKKI
VTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDP
TVGNKETEKPDDNSNSGNTETDNPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEDLLQVKDLFLNTNEILDYSALKY
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFADVMPLVKMDNLESLDLSNNKITNVAPLTEMKNVKSLFLSGNQI
EDVTALAKMEQLDYLNLANNKITNVAPLSNLKNVTYLTLAGNQIEDIKPLYTLPLKDLVLTRNKVKDLSGIDQLNQLQEL
WIGKNEITDVTPLSKMTQLKILNLPNNELKDITPLSSLVNLQKLDLEANYISDLSPVSNLKKLVFLSFVANEIRDVRPVI
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGEISTKIRLKSDNGTYSNGVVKWSTPGEKVYEFGVKDPFADTGIFF
TGSVIQNVVESKDGNTSKEDEKTEVVEFKDVPKGHWSEEAINYLAKEKLFIGYGNGEFGFGDNITRGQVALLIQRYLKLE
NNLEQKTAFTDTKGNMYETAIDAVVQAGIMTGYGNGMFRPDGVLTRYEMSVVLQRVFQLKENENSAENFKDVPNGHWAKG
YVKALVDNKISKGDGEGNFLGDNFVTREQYAQFLYNAIKK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=225, Percent_Identity=30.2222222222222, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI21389483, Length=212, Percent_Identity=30.6603773584906, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI21361633, Length=250, Percent_Identity=31.2, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI55743114, Length=142, Percent_Identity=36.6197183098592, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI209862903, Length=247, Percent_Identity=29.1497975708502, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI40255157, Length=247, Percent_Identity=29.1497975708502, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI288541297, Length=243, Percent_Identity=31.2757201646091, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI288541295, Length=243, Percent_Identity=31.2757201646091, Blast_Score=67, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554124, Length=221, Percent_Identity=30.316742081448, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17536161, Length=205, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531555, Length=220, Percent_Identity=29.5454545454545, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71984630, Length=282, Percent_Identity=28.7234042553192, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322655, Length=227, Percent_Identity=29.9559471365639, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322455, Length=242, Percent_Identity=32.2314049586777, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21358617, Length=181, Percent_Identity=29.8342541436464, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24667524, Length=305, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658034, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17933612, Length=242, Percent_Identity=29.3388429752066, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 85752; Mature: 85752

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50978 NEAT ; PS01072 SLH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNYMKALVVATTLAIPFATYSTPALAALKVEANQSVAAASDRTYDTEIKIYKDQKDEP
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCCCCCCCEEEEEECCCCCH
SMVSQYIKDPKVTIAAGKKIVTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGT
HHHHHHHCCCCEEEECCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCC
KVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGNKETEKPDDNSNSGNTE
EEEEEECCCHHHHCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
TDNPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEDLLQVKDLFLNTNEILDYSALKY
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFADVMPLVKMDNLESLDLSNNKITN
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
VAPLTEMKNVKSLFLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSNLKNVTYLTLA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCCEEEEEEE
GNQIEDIKPLYTLPLKDLVLTRNKVKDLSGIDQLNQLQELWIGKNEITDVTPLSKMTQLK
CCCCHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEEE
ILNLPNNELKDITPLSSLVNLQKLDLEANYISDLSPVSNLKKLVFLSFVANEIRDVRPVI
EEECCCCHHHHCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGEISTKIRLKSDNGTYSNGVVKWSTP
HCCCEEEEEEECCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCEEEECCC
GEKVYEFGVKDPFADTGIFFTGSVIQNVVESKDGNTSKEDEKTEVVEFKDVPKGHWSEEA
CHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCHHHH
INYLAKEKLFIGYGNGEFGFGDNITRGQVALLIQRYLKLENNLEQKTAFTDTKGNMYETA
HHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHH
IDAVVQAGIMTGYGNGMFRPDGVLTRYEMSVVLQRVFQLKENENSAENFKDVPNGHWAKG
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHH
YVKALVDNKISKGDGEGNFLGDNFVTREQYAQFLYNAIKK
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKNYMKALVVATTLAIPFATYSTPALAALKVEANQSVAAASDRTYDTEIKIYKDQKDEP
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCCCCCCCEEEEEECCCCCH
SMVSQYIKDPKVTIAAGKKIVTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGT
HHHHHHHCCCCEEEECCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCC
KVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGNKETEKPDDNSNSGNTE
EEEEEECCCHHHHCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
TDNPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEDLLQVKDLFLNTNEILDYSALKY
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFADVMPLVKMDNLESLDLSNNKITN
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
VAPLTEMKNVKSLFLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSNLKNVTYLTLA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCCEEEEEEE
GNQIEDIKPLYTLPLKDLVLTRNKVKDLSGIDQLNQLQELWIGKNEITDVTPLSKMTQLK
CCCCHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEEE
ILNLPNNELKDITPLSSLVNLQKLDLEANYISDLSPVSNLKKLVFLSFVANEIRDVRPVI
EEECCCCHHHHCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGEISTKIRLKSDNGTYSNGVVKWSTP
HCCCEEEEEEECCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCEEEECCC
GEKVYEFGVKDPFADTGIFFTGSVIQNVVESKDGNTSKEDEKTEVVEFKDVPKGHWSEEA
CHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCHHHH
INYLAKEKLFIGYGNGEFGFGDNITRGQVALLIQRYLKLENNLEQKTAFTDTKGNMYETA
HHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHH
IDAVVQAGIMTGYGNGMFRPDGVLTRYEMSVVLQRVFQLKENENSAENFKDVPNGHWAKG
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHH
YVKALVDNKISKGDGEGNFLGDNFVTREQYAQFLYNAIKK
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]