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The map label for this gene is xerC [H]

Identifier: 218232818

GI number: 218232818

Start: 533224

End: 534150

Strand: Direct

Name: xerC [H]

Synonym: BCB4264_A0562

Alternate gene names: 218232818

Gene position: 533224-534150 (Clockwise)

Preceding gene: 218232722

Following gene: 218232037

Centisome position: 9.84

GC content: 30.96

Gene sequence:

>927_bases
GTGAAAAGACGTGGAGAATTAACAGATGAAGAATTAAAAATTATTAAGAAGAAAATCTCTGATGAAGAGGCTTATGAAAA
ATTTTTTAAGGATTGTTATTTAAGAAACTTGAGACCAGCAACAATAGGGTACTACAAAAATGAATTTCATGGTGCAAAGA
AAATTATAAATAAACAGTTAGTGGAATGGGTGCAGAAGGACATAGAGGATTTAATTCTGAAAAGCAAACAGTTGATGAAG
GTCACAACTATAAATACTCGTTTGCGTGCTCTCCGATCATTTTATAATTTTTTAGATAAGAATAAACTAATCGATAAGAA
TCCAATGAAGAATATCAAATTATTACGTGATAGACAGAAAACAATCGAAACTTTAGATAATCAAGAGATAGAGAAATTGA
TTAAAACAATTAGAAAACAAAAAACGTTTGTTGGTTTTAGAGATGAAGTGATCTTACTTGTTTTTCTAGATACAGGAGTA
AGATTGTCTGAACTAGTTGGGATTAATGTAGAAGATGTTCGGTATAACAAATTAATTATTAGAAGAACAAAAAATCTATT
TGAAAGAACAGTTTATTTATCTGATACGACTCAAGAGCGATTAGAAAGTTATATTAAAGTTCGGGGTGAAGTTGCTACTA
ATAAGCTGTTTATTAGTCAAGATAATAAAGAGTTGAACCCTCATAGCATTCAAACGAGGCTTACAAAGTACGGTAAGGAA
GCTAAGATAAGTAAACGAGTTAGTCCTCATACATTCAGACACACTATGGCAAAAAGAATGATAGTATCTGGCTTAGATGC
TTTTTCTTTAATGCATTTACTTGGTCATACAGATATTACAGTCACTAAAAGATATGTAAATCTATGGGGGCAAGATTTGG
AACAGAAGCATAAAGAATATGGAGCACTGAAAGGTTTGAATCTTTAG

Upstream 100 bases:

>100_bases
CAAGACTTCAACAGAAATGTTGGAGTCTTTTTTTTGTTTTTTCAACACGACAAAATAATCCAAAATCGTGTGCGGCGAAT
CGTGTGCGTAGGAGGTTATA

Downstream 100 bases:

>100_bases
ATTTACGAATATTCAGATAATATATATAATTAAATAAGAGATGGTATACGAGTTTGGCGGCTCTACCATCTCTAAACAGA
AAAAACACAGAAGAATAAAC

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKRRGELTDEELKIIKKKISDEEAYEKFFKDCYLRNLRPATIGYYKNEFHGAKKIINKQLVEWVQKDIEDLILKSKQLMK
VTTINTRLRALRSFYNFLDKNKLIDKNPMKNIKLLRDRQKTIETLDNQEIEKLIKTIRKQKTFVGFRDEVILLVFLDTGV
RLSELVGINVEDVRYNKLIIRRTKNLFERTVYLSDTTQERLESYIKVRGEVATNKLFISQDNKELNPHSIQTRLTKYGKE
AKISKRVSPHTFRHTMAKRMIVSGLDAFSLMHLLGHTDITVTKRYVNLWGQDLEQKHKEYGALKGLNL

Sequences:

>Translated_308_residues
MKRRGELTDEELKIIKKKISDEEAYEKFFKDCYLRNLRPATIGYYKNEFHGAKKIINKQLVEWVQKDIEDLILKSKQLMK
VTTINTRLRALRSFYNFLDKNKLIDKNPMKNIKLLRDRQKTIETLDNQEIEKLIKTIRKQKTFVGFRDEVILLVFLDTGV
RLSELVGINVEDVRYNKLIIRRTKNLFERTVYLSDTTQERLESYIKVRGEVATNKLFISQDNKELNPHSIQTRLTKYGKE
AKISKRVSPHTFRHTMAKRMIVSGLDAFSLMHLLGHTDITVTKRYVNLWGQDLEQKHKEYGALKGLNL
>Mature_308_residues
MKRRGELTDEELKIIKKKISDEEAYEKFFKDCYLRNLRPATIGYYKNEFHGAKKIINKQLVEWVQKDIEDLILKSKQLMK
VTTINTRLRALRSFYNFLDKNKLIDKNPMKNIKLLRDRQKTIETLDNQEIEKLIKTIRKQKTFVGFRDEVILLVFLDTGV
RLSELVGINVEDVRYNKLIIRRTKNLFERTVYLSDTTQERLESYIKVRGEVATNKLFISQDNKELNPHSIQTRLTKYGKE
AKISKRVSPHTFRHTMAKRMIVSGLDAFSLMHLLGHTDITVTKRYVNLWGQDLEQKHKEYGALKGLNL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=25.0847457627119, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790244, Length=266, Percent_Identity=25.5639097744361, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=27.3809523809524, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36409; Mature: 36409

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRGELTDEELKIIKKKISDEEAYEKFFKDCYLRNLRPATIGYYKNEFHGAKKIINKQL
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEWVQKDIEDLILKSKQLMKVTTINTRLRALRSFYNFLDKNKLIDKNPMKNIKLLRDRQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
TIETLDNQEIEKLIKTIRKQKTFVGFRDEVILLVFLDTGVRLSELVGINVEDVRYNKLII
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHHH
RRTKNLFERTVYLSDTTQERLESYIKVRGEVATNKLFISQDNKELNPHSIQTRLTKYGKE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCH
AKISKRVSPHTFRHTMAKRMIVSGLDAFSLMHLLGHTDITVTKRYVNLWGQDLEQKHKEY
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GALKGLNL
HCCCCCCC
>Mature Secondary Structure
MKRRGELTDEELKIIKKKISDEEAYEKFFKDCYLRNLRPATIGYYKNEFHGAKKIINKQL
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEWVQKDIEDLILKSKQLMKVTTINTRLRALRSFYNFLDKNKLIDKNPMKNIKLLRDRQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
TIETLDNQEIEKLIKTIRKQKTFVGFRDEVILLVFLDTGVRLSELVGINVEDVRYNKLII
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHHH
RRTKNLFERTVYLSDTTQERLESYIKVRGEVATNKLFISQDNKELNPHSIQTRLTKYGKE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCH
AKISKRVSPHTFRHTMAKRMIVSGLDAFSLMHLLGHTDITVTKRYVNLWGQDLEQKHKEY
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GALKGLNL
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA