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The map label for this gene is ykvZ [H]

Identifier: 218232692

GI number: 218232692

Start: 204331

End: 205308

Strand: Direct

Name: ykvZ [H]

Synonym: BCB4264_A0234

Alternate gene names: 218232692

Gene position: 204331-205308 (Clockwise)

Preceding gene: 218230978

Following gene: 218233455

Centisome position: 3.77

GC content: 35.07

Gene sequence:

>978_bases
ATGGCTAATATTAAAGATATCGCAAAGATGGCGGGAGTTTCAGTTACGACTGTTTCGAGAGTGTTGAATGATCACCCATA
TGTAAGTGAAGAAAAAAGAAAAGCGGTTATAGAGATAGTTGAGAAATTGAATTACTCGCAAAACGCAAATGCTGTTCATT
TATCAAAAGGGAAGACGAATATTGTTGGTGTAATTCTACCTTACATTAATCACCCGAGCTTTGATGCAATGGTAGGGGGA
ATGATGGAGGGAGCGTTAACTCATAATTACAGGGTGCTACTTTGCCAAACGAATTATAATAAAAAAGAAGAAATGAAAAG
TTTACATATGTTAAAAACAAAACAATTGGATGGTCTTATTATTTGTTCACGTGCAAATGATTGGGAAACGATAGAACCGT
ATGCTTCTTACGGCACAATAATTGCTTGTGAAGATAATGATATTTCAAACATCTCAAGTGTATATACGAATCATTCAGCG
GCCTTTCAATTAGGAATGGATTATTTGATTGAGAAAGGTTATAAAAAAATTGGTTATTGTACGGGAAGAAAATTAGGGCC
AAGTAGTCAAAAGCGTTTTGATGTCTATAAACAGCAATTACAATCTATAGACGAAGAGGTTAATGAAGAATGGATTTTTA
CAGAATGTTTTACACTAGAAGATGGTGTAAAAGTGGCTCATAAGTTAAAAGAGATGCAGGATCTTCCTGAAGCATTAATA
GTAGCAGGCGATGAAGTTGCGATTGGGGTTATGACAGAGGTTGAAAAATTAGGGATTCAAGTTCCTGAGGATTTAGCGAT
TATTGGCTTTGATAATCAACCTATCTCGCAAGTGTTACAATTGACAACTATTGATCAAAATTTAAAGGAGATAGGGAAAA
CTGCTTTTGAAATGTTGCATAGAAAAGTGAATGAAGAGAGTTCTGAACAAGAAAAGCTGGAAATTCCATACGAACTTGTG
GAACGCTCTACAGTTTAA

Upstream 100 bases:

>100_bases
AAAAATTACACTTTTGTAAGAGAAACGAATGAAGGTGTAATGATAAGAAGATTTGACATATGTTCATGGGATTCATTAAG
TTAAAGATAGAGGTGAGTGT

Downstream 100 bases:

>100_bases
TTTTAATCCGTTATGTGTATAATCGCATAACGGATTATTTTTTTGAAATACCTTTGACAGGAAACGCGTTTCATACTTTA
TAAAGGAGTTAAACCGGTTT

Product: sugar-binding transcriptional regulator, LacI family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTNIVGVILPYINHPSFDAMVGG
MMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLIICSRANDWETIEPYASYGTIIACEDNDISNISSVYTNHSA
AFQLGMDYLIEKGYKKIGYCTGRKLGPSSQKRFDVYKQQLQSIDEEVNEEWIFTECFTLEDGVKVAHKLKEMQDLPEALI
VAGDEVAIGVMTEVEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKTAFEMLHRKVNEESSEQEKLEIPYELV
ERSTV

Sequences:

>Translated_325_residues
MANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTNIVGVILPYINHPSFDAMVGG
MMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLIICSRANDWETIEPYASYGTIIACEDNDISNISSVYTNHSA
AFQLGMDYLIEKGYKKIGYCTGRKLGPSSQKRFDVYKQQLQSIDEEVNEEWIFTECFTLEDGVKVAHKLKEMQDLPEALI
VAGDEVAIGVMTEVEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKTAFEMLHRKVNEESSEQEKLEIPYELV
ERSTV
>Mature_324_residues
ANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTNIVGVILPYINHPSFDAMVGGM
MEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLIICSRANDWETIEPYASYGTIIACEDNDISNISSVYTNHSAA
FQLGMDYLIEKGYKKIGYCTGRKLGPSSQKRFDVYKQQLQSIDEEVNEEWIFTECFTLEDGVKVAHKLKEMQDLPEALIV
AGDEVAIGVMTEVEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKTAFEMLHRKVNEESSEQEKLEIPYELVE
RSTV

Specific function: Transcriptional Repressor For The Ribose Rbsdacbk Operon. Rbsr Binds To A Region Of Perfect Dyad Symmetry Spanning The Rbs Operon Transcriptional Start Site. The Affinity For The Rbs Operator Is Reduced By Addition Of Ribose, Consistent With Ribose Being

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=27.3273273273273, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=28.0966767371601, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790369, Length=303, Percent_Identity=31.6831683168317, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=28.75, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788474, Length=314, Percent_Identity=26.7515923566879, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=26.0479041916168, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=27.6094276094276, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789068, Length=281, Percent_Identity=28.4697508896797, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994940, Length=322, Percent_Identity=23.9130434782609, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789456, Length=352, Percent_Identity=25.8522727272727, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=23.1231231231231, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787906, Length=332, Percent_Identity=21.0843373493976, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786268, Length=322, Percent_Identity=20.8074534161491, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790689, Length=338, Percent_Identity=22.4852071005917, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36586; Mature: 36455

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTN
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
IVGVILPYINHPSFDAMVGGMMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLI
EEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEE
ICSRANDWETIEPYASYGTIIACEDNDISNISSVYTNHSAAFQLGMDYLIEKGYKKIGYC
EEECCCCCCCCCCHHCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
TGRKLGPSSQKRFDVYKQQLQSIDEEVNEEWIFTECFTLEDGVKVAHKLKEMQDLPEALI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHE
VAGDEVAIGVMTEVEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKTAFEMLH
ECCCCEEEHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKVNEESSEQEKLEIPYELVERSTV
HHHCCCCCCHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
ANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTN
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
IVGVILPYINHPSFDAMVGGMMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLI
EEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEE
ICSRANDWETIEPYASYGTIIACEDNDISNISSVYTNHSAAFQLGMDYLIEKGYKKIGYC
EEECCCCCCCCCCHHCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
TGRKLGPSSQKRFDVYKQQLQSIDEEVNEEWIFTECFTLEDGVKVAHKLKEMQDLPEALI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHE
VAGDEVAIGVMTEVEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKTAFEMLH
ECCCCEEEHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKVNEESSEQEKLEIPYELVERSTV
HHHCCCCCCHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]