Click here to switch to the map view.

The map label for this gene is prsA [H]

Identifier: 218232569

GI number: 218232569

Start: 1184231

End: 1185088

Strand: Reverse

Name: prsA [H]

Synonym: BCB4264_A1215

Alternate gene names: 218232569

Gene position: 1185088-1184231 (Counterclockwise)

Preceding gene: 218235070

Following gene: 218234684

Centisome position: 21.87

GC content: 32.05

Gene sequence:

>858_bases
ATGAGAGGGAAACATATTTTCATTATTACTGCACTAATAAGTATATTGATGCTATCTGCTTGCGAACAAAAGAATGGCTC
AGCTACAGTCGCTACAGCAACAGACTCCACCATTACAAAGGATAACTTCGAAAAACAATTGAAAGATCGTTACGGAAAAG
ACATGCTATACGAAATGATGGCACAAGACGTCATCACAAAAAAATATAAAGTACCTGATGAAGAGGTAAATAAAGAAGTA
GAAAAAGTAAAAAAACAATATGGAGATCAATTCAAAAAAGTATTAGAAAATTATGGTTTAAAAGATGAAGAGGATTTCAA
AAATCAAATTAAGTTCAAACTTGCTATGAATGAAGCGATTAAGAAAAGCATTACAGAAAAAGACATAAAAGACCACTATA
AGCCAGAAATTAAAGCGAGTCACATTTTAGTAAGTGACGAAAATGAAGCGAAAGAAATAAAGAGTAAACTAGATGCTGGT
GCTTCATTTGAAGAATTAGCAAAACAAGAATCACAAGATCTACTATCAAAAGATAAAGGCGGAGACCTTGGATACTTCAA
TTCAGGTACAATGGCTCCTGAATTCGAAACGGCTGCCTACAAACTAAATGTTGGACAAATTAGCAATCCCGTAAAATCAT
CAAACGGTTATCACGTTATTAAATTAACTGATAAAAAAGATTTAAAACCTTACGATGAAGTAAAAAACTCTATTCGCAAA
AACTTAGAGGAAGAACGTACTGCTGATCCTGTATTCAGCAAAAAATTGTTACAAGAGGAATTAAAAAAGGCAAATATTAA
AATAAATGATAGTGATTTGAAAGATACATTTACTCTTGTTTCTCCGCAAGGAAATTAA

Upstream 100 bases:

>100_bases
GTACTTTTTTACATTTTAAAGGAAAAAAACATTAAAAATTCACTTCATGTTCACTTCTATATTCTACAATAGCGATAACA
TATTCGGATGAGGTGTTGGC

Downstream 100 bases:

>100_bases
AAAAAGCACACCCTTATCTTTTTAGATAAGGGTGTGCTTTTTAATCTTTCATCTTATTTCTTAAAGTAAGTCCAACCTTC
TTCTTGGTAAACCTTTTCTT

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MRGKHIFIITALISILMLSACEQKNGSATVATATDSTITKDNFEKQLKDRYGKDMLYEMMAQDVITKKYKVPDEEVNKEV
EKVKKQYGDQFKKVLENYGLKDEEDFKNQIKFKLAMNEAIKKSITEKDIKDHYKPEIKASHILVSDENEAKEIKSKLDAG
ASFEELAKQESQDLLSKDKGGDLGYFNSGTMAPEFETAAYKLNVGQISNPVKSSNGYHVIKLTDKKDLKPYDEVKNSIRK
NLEEERTADPVFSKKLLQEELKKANIKINDSDLKDTFTLVSPQGN

Sequences:

>Translated_285_residues
MRGKHIFIITALISILMLSACEQKNGSATVATATDSTITKDNFEKQLKDRYGKDMLYEMMAQDVITKKYKVPDEEVNKEV
EKVKKQYGDQFKKVLENYGLKDEEDFKNQIKFKLAMNEAIKKSITEKDIKDHYKPEIKASHILVSDENEAKEIKSKLDAG
ASFEELAKQESQDLLSKDKGGDLGYFNSGTMAPEFETAAYKLNVGQISNPVKSSNGYHVIKLTDKKDLKPYDEVKNSIRK
NLEEERTADPVFSKKLLQEELKKANIKINDSDLKDTFTLVSPQGN
>Mature_285_residues
MRGKHIFIITALISILMLSACEQKNGSATVATATDSTITKDNFEKQLKDRYGKDMLYEMMAQDVITKKYKVPDEEVNKEV
EKVKKQYGDQFKKVLENYGLKDEEDFKNQIKFKLAMNEAIKKSITEKDIKDHYKPEIKASHILVSDENEAKEIKSKLDAG
ASFEELAKQESQDLLSKDKGGDLGYFNSGTMAPEFETAAYKLNVGQISNPVKSSNGYHVIKLTDKKDLKPYDEVKNSIRK
NLEEERTADPVFSKKLLQEELKKANIKINDSDLKDTFTLVSPQGN

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=175, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786238, Length=110, Percent_Identity=35.4545454545455, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322478, Length=102, Percent_Identity=44.1176470588235, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 32364; Mature: 32364

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKHIFIITALISILMLSACEQKNGSATVATATDSTITKDNFEKQLKDRYGKDMLYEMM
CCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHH
AQDVITKKYKVPDEEVNKEVEKVKKQYGDQFKKVLENYGLKDEEDFKNQIKFKLAMNEAI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KKSITEKDIKDHYKPEIKASHILVSDENEAKEIKSKLDAGASFEELAKQESQDLLSKDKG
HHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
GDLGYFNSGTMAPEFETAAYKLNVGQISNPVKSSNGYHVIKLTDKKDLKPYDEVKNSIRK
CCCCCCCCCCCCCCCCHHEEEEEHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
NLEEERTADPVFSKKLLQEELKKANIKINDSDLKDTFTLVSPQGN
HHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEECCCCC
>Mature Secondary Structure
MRGKHIFIITALISILMLSACEQKNGSATVATATDSTITKDNFEKQLKDRYGKDMLYEMM
CCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHH
AQDVITKKYKVPDEEVNKEVEKVKKQYGDQFKKVLENYGLKDEEDFKNQIKFKLAMNEAI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KKSITEKDIKDHYKPEIKASHILVSDENEAKEIKSKLDAGASFEELAKQESQDLLSKDKG
HHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
GDLGYFNSGTMAPEFETAAYKLNVGQISNPVKSSNGYHVIKLTDKKDLKPYDEVKNSIRK
CCCCCCCCCCCCCCCCHHEEEEEHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
NLEEERTADPVFSKKLLQEELKKANIKINDSDLKDTFTLVSPQGN
HHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]