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The map label for this gene is yfhA [H]

Identifier: 218232546

GI number: 218232546

Start: 641780

End: 642838

Strand: Direct

Name: yfhA [H]

Synonym: BCB4264_A0654

Alternate gene names: 218232546

Gene position: 641780-642838 (Clockwise)

Preceding gene: 218232282

Following gene: 218235984

Centisome position: 11.84

GC content: 39.94

Gene sequence:

>1059_bases
ATGAAGAAATATATTCCGTTTCGTATAGGAAAAGGTGAGCTCTCGTTTTTAATGTATAAACGAGCTTGTCTCGTCTTGTT
AAGTTTACTAGTTGTTTTAATAGGATTATTCTTTGCGAGCGCAGGTATGGGAGACATGAAAATTGCTCCTTATGACGTAT
GGCAAGCAATTACTGGAAATGGCGATGCGATGTCAAATATGGTTGTGAATAAGTTTCGTATGCCACGTATTTTAATTGCT
ATCCTCGTAGGAATTGCGCTTGCTGTAGCAGGATGTATTTTACAAGGTCTCGTTCGAAATCCACTTGCTTCTCCGGATAT
CATCGGGATTACGGGCGGGGCAAGTGTTGCAGTTGTATTGTTTTTAGCTATATTTAGTGATAAAAATAATGCGCTAACTG
TAAGTATTCATTATATGCCGTTAGCAGCCTTTGTTGGGGCAACGATTGTGGCGCTTTTTGTATATTTATTTGCATGGAGA
AATGACGGGTTATCGCCTATTAGTCTTGTTTTAATTGGTGTGGGGTTTTGGGCATTAACGAAAGCGGCAACGACTTTGTT
TATGTTGTTAGCACCAATTTATCAAGCGAGTCAAGCGAATGTATGGATTACAGGTACTGTTTATGGTTCTTCATGGCAAA
ACGTTATGGTGCTTGCACCGTGGGTTCTCATTTTAACGGTAATATCATTTATAGCTGCTAGACATTTAAATGCGCAAGAG
CTAGGGGATGATATTGCGGTAGGACTTGGTGTTCCTTTAACGAAGTCACGCGTATCCATGTTATTACTTAGTACGGCTTT
AATTGGGGGAGCAGTTGCCTTCGCCGGAGGAATTGGATTTGTCGGTTTAATGGCACCTCATATTTCACGAAGGCTAGTTG
GTTCTTTATACGGTGCATTACTCCCAGTTGCAGCTATTGTTGGTGCAATTCTAGTACTTGCTGCAGATTTAATTGGGCGT
ACAGTTTTCACACCACTTGAAATTCCAGCAGGGGTATTTACATCAGCAATTGGTGCACCTTATTTTATTTATTTACTTTA
TAAAAGTCGGAATTCATAA

Upstream 100 bases:

>100_bases
GATATGTCATTATGCCACAAGAAGTACCAGTAGGAGTTATGACAGCATTTATTGGAGCTCCATTCTTTATTTATATTGCA
CGTAAGAGAGGGCTTAGCAA

Downstream 100 bases:

>100_bases
AGGGAGATGAATATGCAAAAAGCATTGGAGACGAAACGTTTGACGTTGTCTTATGGTGAAACAATTATTATCGATGAGTT
GAATTTAGAAATTCCAAAAG

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKKYIPFRIGKGELSFLMYKRACLVLLSLLVVLIGLFFASAGMGDMKIAPYDVWQAITGNGDAMSNMVVNKFRMPRILIA
ILVGIALAVAGCILQGLVRNPLASPDIIGITGGASVAVVLFLAIFSDKNNALTVSIHYMPLAAFVGATIVALFVYLFAWR
NDGLSPISLVLIGVGFWALTKAATTLFMLLAPIYQASQANVWITGTVYGSSWQNVMVLAPWVLILTVISFIAARHLNAQE
LGDDIAVGLGVPLTKSRVSMLLLSTALIGGAVAFAGGIGFVGLMAPHISRRLVGSLYGALLPVAAIVGAILVLAADLIGR
TVFTPLEIPAGVFTSAIGAPYFIYLLYKSRNS

Sequences:

>Translated_352_residues
MKKYIPFRIGKGELSFLMYKRACLVLLSLLVVLIGLFFASAGMGDMKIAPYDVWQAITGNGDAMSNMVVNKFRMPRILIA
ILVGIALAVAGCILQGLVRNPLASPDIIGITGGASVAVVLFLAIFSDKNNALTVSIHYMPLAAFVGATIVALFVYLFAWR
NDGLSPISLVLIGVGFWALTKAATTLFMLLAPIYQASQANVWITGTVYGSSWQNVMVLAPWVLILTVISFIAARHLNAQE
LGDDIAVGLGVPLTKSRVSMLLLSTALIGGAVAFAGGIGFVGLMAPHISRRLVGSLYGALLPVAAIVGAILVLAADLIGR
TVFTPLEIPAGVFTSAIGAPYFIYLLYKSRNS
>Mature_352_residues
MKKYIPFRIGKGELSFLMYKRACLVLLSLLVVLIGLFFASAGMGDMKIAPYDVWQAITGNGDAMSNMVVNKFRMPRILIA
ILVGIALAVAGCILQGLVRNPLASPDIIGITGGASVAVVLFLAIFSDKNNALTVSIHYMPLAAFVGATIVALFVYLFAWR
NDGLSPISLVLIGVGFWALTKAATTLFMLLAPIYQASQANVWITGTVYGSSWQNVMVLAPWVLILTVISFIAARHLNAQE
LGDDIAVGLGVPLTKSRVSMLLLSTALIGGAVAFAGGIGFVGLMAPHISRRLVGSLYGALLPVAAIVGAILVLAADLIGR
TVFTPLEIPAGVFTSAIGAPYFIYLLYKSRNS

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=324, Percent_Identity=36.4197530864198, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=35.7575757575758, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786347, Length=286, Percent_Identity=38.8111888111888, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786805, Length=299, Percent_Identity=35.4515050167224, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790741, Length=296, Percent_Identity=32.4324324324324, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788004, Length=308, Percent_Identity=34.0909090909091, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37264; Mature: 37264

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYIPFRIGKGELSFLMYKRACLVLLSLLVVLIGLFFASAGMGDMKIAPYDVWQAITGN
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
GDAMSNMVVNKFRMPRILIAILVGIALAVAGCILQGLVRNPLASPDIIGITGGASVAVVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
FLAIFSDKNNALTVSIHYMPLAAFVGATIVALFVYLFAWRNDGLSPISLVLIGVGFWALT
HHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KAATTLFMLLAPIYQASQANVWITGTVYGSSWQNVMVLAPWVLILTVISFIAARHLNAQE
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LGDDIAVGLGVPLTKSRVSMLLLSTALIGGAVAFAGGIGFVGLMAPHISRRLVGSLYGAL
CCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPVAAIVGAILVLAADLIGRTVFTPLEIPAGVFTSAIGAPYFIYLLYKSRNS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
>Mature Secondary Structure
MKKYIPFRIGKGELSFLMYKRACLVLLSLLVVLIGLFFASAGMGDMKIAPYDVWQAITGN
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
GDAMSNMVVNKFRMPRILIAILVGIALAVAGCILQGLVRNPLASPDIIGITGGASVAVVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
FLAIFSDKNNALTVSIHYMPLAAFVGATIVALFVYLFAWRNDGLSPISLVLIGVGFWALT
HHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KAATTLFMLLAPIYQASQANVWITGTVYGSSWQNVMVLAPWVLILTVISFIAARHLNAQE
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LGDDIAVGLGVPLTKSRVSMLLLSTALIGGAVAFAGGIGFVGLMAPHISRRLVGSLYGAL
CCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPVAAIVGAILVLAADLIGRTVFTPLEIPAGVFTSAIGAPYFIYLLYKSRNS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]