Click here to switch to the map view.

The map label for this gene is rocF [H]

Identifier: 218232479

GI number: 218232479

Start: 158385

End: 159278

Strand: Direct

Name: rocF [H]

Synonym: BCB4264_A0186

Alternate gene names: 218232479

Gene position: 158385-159278 (Clockwise)

Preceding gene: 218230811

Following gene: 218234742

Centisome position: 2.92

GC content: 37.02

Gene sequence:

>894_bases
ATGAAAAAAGAAATCTCAGTTATTGGAGTTCCAATGGATTTAGGACAGATGCGTCGTGGAGTTGATATGGGACCGAGCGC
GATCCGTTATGCAGGGGTAATTGAAAGAATTGAAGAAATTGGATATGACGTTAAAGATATGGGAGATATATGTATAGAGA
GAGAAAAAGAGATAGATGAAAATACAAAATTAAGAAACCTTACACAAGTTGCAACTGTATGTAATGAATTAGCAAGTAAG
GTGGATCATATTATAGAAGAAGGTCGTTTTCCACTTGTATTAGGTGGTGACCATAGTATTGCTATCGGTACATTAGCTGG
TGTAGCAAAACATTATAAAAACTTAGGCGTTATTTGGTATGATGCACACGGTGATTTAAATACAGAGGAAACTTCACCAT
CTGGAAATATTCATGGTATGTCACTTGCAGCAAGTTTAGGTTATGGACATTCTTCACTTGTAGATTTATACGGAGCATAT
CCAAAGGTGAAAAAAGAGAATGTCGTAATTATCGGTGCGCGTGCATTGGATGAAGGAGAAAAAGATTTCATTCGCAATGA
AGGTATTAAAGTGTTCTCAATGCATGAAATTGATCGTATGGGGATGACGGCTGTGATGGAAGAAACAATCGCATATTTAT
CTCATACCGATGGTGTACACTTATCATTAGATTTAGATGGTCTTGATCCTCATGATGCACCAGGTGTTGGAACACCTGTA
ATTGGCGGTCTATCTTATCGTGAAAGTCATTTGGCGATGGAAATGTTAGCAGAAGCTGATATTATCACATCTGCTGAATT
TGTTGAGGTAAATACGATTTTAGATGAGAGAAATAGAACGGCAACAACAGCAGTTGCTTTAATGGGTTCTTTATTCGGTG
AAAAACTAAAATAA

Upstream 100 bases:

>100_bases
GTGAATAAATTGTATATCCATACAGAAAAATGTCGAGTTGAGTCAGACTATATAAAAGATTTAAAATATTTAGTGAAGGC
ATAAAAGGGGGATACTATCT

Downstream 100 bases:

>100_bases
ATGTAAGAAAAGCAACTGAGAAGTTGCTTTTTTTATTTGAAAATAAGCGTATAATAATGATTTATATTATACTGTACAAT
AAAAATGTTTGACATCTTAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENTKLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIITSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK

Sequences:

>Translated_297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENTKLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIITSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK
>Mature_297_residues
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENTKLRNLTQVATVCNELASK
VDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDAHGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYGAY
PKVKKENVVIIGARALDEGEKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
IGGLSYRESHLAMEMLAEADIITSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=300, Percent_Identity=40.6666666666667, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI4502215, Length=300, Percent_Identity=38.6666666666667, Blast_Score=205, Evalue=4e-53,
Organism=Homo sapiens, GI37537722, Length=300, Percent_Identity=27.6666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789306, Length=281, Percent_Identity=25.2669039145907, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71996843, Length=236, Percent_Identity=36.0169491525424, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6325146, Length=323, Percent_Identity=32.1981424148607, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24638886, Length=309, Percent_Identity=30.42071197411, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32311; Mature: 32311

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDE
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
NTKLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYGAYPKVKKENVVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCC
KDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIITSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDE
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
NTKLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEE
DAHGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYGAYPKVKKENVVIIGARALDEGE
ECCCCCCCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCC
KDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYLSHTDGVHLSLDLDGLDPHDAPGVGTPV
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCC
IGGLSYRESHLAMEMLAEADIITSAEFVEVNTILDERNRTATTAVALMGSLFGEKLK
CCCCCHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]