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The map label for this gene is yciC [H]

Identifier: 218232358

GI number: 218232358

Start: 1841156

End: 1842079

Strand: Direct

Name: yciC [H]

Synonym: BCB4264_A1930

Alternate gene names: 218232358

Gene position: 1841156-1842079 (Clockwise)

Preceding gene: 218233000

Following gene: 218233834

Centisome position: 33.98

GC content: 32.03

Gene sequence:

>924_bases
ATGAATAAAGTGGAGATTCATATATTAGGTGGTTTTTTAGGTAGTGGAAAATCAACATTATTACAAAATTTATTGTTAGC
AGAGAAAAAGAAGAATAGAAAAGTTGCAGTATTAATGAATGAAATTGGTGAATACTCAGTAGATACAGATATTATTGGAA
AAGAGAATGTTTTAAGAGAACTTCTTAAAGGATGTATTTGTTGTACGTTAAAAGAAGAGCTTGAAATACAATTACATTCG
TTATACCAACAAGAAAGACCAGATGTAATTTATATAGAAACGACAGGTGTTGCGCATCCAATTGAAGTGTTAGACGCGTG
TGTCTCGCCAATTTTAGCTCCTTTTCTGGAAGTGAAATCAATTGTAGTCGTTTTAGATGCAGTAAGGTGGTTAAATCGAA
GTATATTAAGTGCAAATGTACAACAGCTATTGCATGAGCAACTGAAATTTGGTAGTCACATTCTTGTTAATAAAGCAGAT
TTACTAACAGATGAAGATAAGAATACAGTATTTGAAGAAGTAAAGGCAATAAATGATCATGCGAAAATGTATGAGACAAA
GTATTGTAATATATCTTTAAAAGATATAGAAGAAGCAGAATTTCCAAATGATGAGGAACACGAGACACTACATGTCAAAC
AGCATTTACATATACAAACAATGACATATCAATTTACGAAACCGATTGATCAAGACAAATTATATGAATGGCTTTCGAAT
TTACCAGATAGTATTTATCGAGTGAAAGGTTTTGTGAAATTCCATGGAGATAAATACCCTCACCTATTCCAATATTCGTT
CGGAGTACCAACTTTATTAGAACAAGACTTCGGTTTCCCGACAAACTTAGTAGTAATAGGAGAAGGACTAGATAAGAAAC
AATTGGCTGAAGGGTTAGAGAAAGTAGAACTTAACTCTAATTAA

Upstream 100 bases:

>100_bases
TATATTTACAAAAGGTCATTCTTTTAATAAAATGATAAATATAAATCGTAATTATTACGCTTTGAATACATTTGAAGTAA
AGAAATGGATGGTCGGTTGA

Downstream 100 bases:

>100_bases
GGGGAAAAGACTAACTTAAAAATAAGTTAGTCTTTTTGTATGGTCATTACTGAAATGAAACAGTATTTTCAATTGGATTG
CAGAATATATATTGATTGTA

Product: cobalamin synthesis protein/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLHEQLKFGSHILVNKAD
LLTDEDKNTVFEEVKAINDHAKMYETKYCNISLKDIEEAEFPNDEEHETLHVKQHLHIQTMTYQFTKPIDQDKLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN

Sequences:

>Translated_307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLHEQLKFGSHILVNKAD
LLTDEDKNTVFEEVKAINDHAKMYETKYCNISLKDIEEAEFPNDEEHETLHVKQHLHIQTMTYQFTKPIDQDKLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN
>Mature_307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLHEQLKFGSHILVNKAD
LLTDEDKNTVFEEVKAINDHAKMYETKYCNISLKDIEEAEFPNDEEHETLHVKQHLHIQTMTYQFTKPIDQDKLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=205, Percent_Identity=30.2439024390244, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33469141, Length=205, Percent_Identity=30.2439024390244, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI148727351, Length=334, Percent_Identity=26.6467065868263, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223941779, Length=203, Percent_Identity=30.5418719211823, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI146231952, Length=205, Percent_Identity=30.2439024390244, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI223941776, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788499, Length=215, Percent_Identity=29.3023255813954, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082430, Length=299, Percent_Identity=28.0936454849498, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35060; Mature: 35060

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRE
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHH
LLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IVVVLDAVRWLNRSILSANVQQLLHEQLKFGSHILVNKADLLTDEDKNTVFEEVKAINDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCCHHHHHHHHHHHHHH
AKMYETKYCNISLKDIEEAEFPNDEEHETLHVKQHLHIQTMTYQFTKPIDQDKLYEWLSN
HHHHHHHCCCEEHHCCHHCCCCCCCCCCEEEHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLE
CCHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
KVELNSN
HHCCCCC
>Mature Secondary Structure
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRE
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHH
LLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IVVVLDAVRWLNRSILSANVQQLLHEQLKFGSHILVNKADLLTDEDKNTVFEEVKAINDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCCHHHHHHHHHHHHHH
AKMYETKYCNISLKDIEEAEFPNDEEHETLHVKQHLHIQTMTYQFTKPIDQDKLYEWLSN
HHHHHHHCCCEEHHCCHHCCCCCCCCCCEEEHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLE
CCHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
KVELNSN
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]