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The map label for this gene is yacO [H]

Identifier: 218232294

GI number: 218232294

Start: 107298

End: 108041

Strand: Direct

Name: yacO [H]

Synonym: BCB4264_A0112

Alternate gene names: 218232294

Gene position: 107298-108041 (Clockwise)

Preceding gene: 218234559

Following gene: 218232863

Centisome position: 1.98

GC content: 37.5

Gene sequence:

>744_bases
ATGACTAGTGAATATATTATCGGACGTAACCCTGTAATTGAAGCGTTAAGATCAGGGAGAGATATTAATAAAATTTGGAT
CGCAGAAGGTGCTGCCAAAGGACAAGTACAAATTGTACTAGCATTAGCGAAAGAAAATAAGATTATTTTACAACATGCAC
CAAAGAAAAAGTTAGATCAATTAGTTGAGGGTAATCATCAAGGTGTAATTGCTCAAGTAGCTGCATATCAGTATGCAGAG
TTAGAAGATTTATTCAAAGTGGCAGAAAAACGTAATGAAGATCCATTCTTCTTGATTTTAGATGAGATTGAAGATCCGCA
TAACCTAGGTTCTATTATGCGTACTGCTGATGCAACAGGAGCTCATGGAATTATTATTCCGAAGAGAAGAGCTGTGGGAC
TTACCGCATCAGTTGCGAAAGCATCAACAGGAGCGATTGAATACATTCCTGTTGCGCGCGTAACAAACTTATCTCGTACA
ATTGATGAATTAAAAGAGCGTGGACTTTGGATTGCTGGTACAGATGCCAAAGGGAAAACGGATTACCGTAATTTAGATGG
TACAATGCCGATTGGATTAGTAATTGGTAGTGAAGGAAAAGGTATGAGTCGTATTATTGGTGAAAAGTGTGATTTCTTAA
TCACTCTACCGATGGTTGGTAAAGTTACATCCTTAAATGCTTCAGTAGCCGCAAGTTTGTTAATGTATGAGGTATATCGT
AAACGTCACGAAATTGGTAAATAA

Upstream 100 bases:

>100_bases
TAATTGGTTACCATCATTTATTAAATAATCGTGAAAGATTAGACGAAATTGTATATAAGGCAATAGCAGTTTTAGAAGAA
AAGGAAGGGGGCACATCATC

Downstream 100 bases:

>100_bases
AAAATGAACGATATTTTAATCGTTGACGGCTACAACATTATCGGAGCTTGGGGAGATTTGAAGAAACTGCGGGATGTAGA
TTTACAATCATCAAGAGATG

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEGNHQGVIAQVAAYQYAE
LEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRT
IDELKERGLWIAGTDAKGKTDYRNLDGTMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
KRHEIGK

Sequences:

>Translated_247_residues
MTSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEGNHQGVIAQVAAYQYAE
LEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRT
IDELKERGLWIAGTDAKGKTDYRNLDGTMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
KRHEIGK
>Mature_246_residues
TSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEGNHQGVIAQVAAYQYAEL
EDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTI
DELKERGLWIAGTDAKGKTDYRNLDGTMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYRK
RHEIGK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=258, Percent_Identity=27.1317829457364, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1790623, Length=247, Percent_Identity=38.8663967611336, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI1790083, Length=159, Percent_Identity=30.8176100628931, Blast_Score=88, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17555908, Length=258, Percent_Identity=29.8449612403101, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27018; Mature: 26887

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQ
CCCCEECCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEECCCEEEEECCCHHHHHH
LVEGNHQGVIAQVAAYQYAELEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
AHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTIDELKERGLWIAGTDAKGKT
CCEEEEECCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
DYRNLDGTMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
CCCCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHH
KRHEIGK
HHHHCCC
>Mature Secondary Structure 
TSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQ
CCCEECCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEECCCEEEEECCCHHHHHH
LVEGNHQGVIAQVAAYQYAELEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
AHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTIDELKERGLWIAGTDAKGKT
CCEEEEECCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
DYRNLDGTMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
CCCCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHH
KRHEIGK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]