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The map label for this gene is mraY [H]

Identifier: 218232257

GI number: 218232257

Start: 3936280

End: 3937254

Strand: Reverse

Name: mraY [H]

Synonym: BCB4264_A4014

Alternate gene names: 218232257

Gene position: 3937254-3936280 (Counterclockwise)

Preceding gene: 218233439

Following gene: 218232675

Centisome position: 72.66

GC content: 36.82

Gene sequence:

>975_bases
GTGCTTGAGCAAGGTTTATTAGTAACGGCTGGGGTAGCATTCTTAATTTCTGTTGCCCTTTCGCCATTGTTTATTCCATT
TTTAAGAAAATTAAAGTTCGGACAGAGTATTCGTGATGAGGGACCGAAGTCACATCAAAAAAAATCAGGGACACCGACAA
TGGGTGGTATCGTCATATACGTATCTATGATGGTAACTTCACTTATTATGGCGATTAAGTTTAATTATTTAGGTGCAGAG
GTTTCATTATTACTATTAGTGACGTTTGGTTACGGATTGATTGGATTTTTAGATGACTACATAAAGGTAGTTAAGAAGAG
AAATCTTGGTTTAACATCAAAGCAAAAATTAGTAGGTCAGCTTGTTATTGCTATTGCATTCTTTTTAATTGGAAAAGGGC
AAGCGTTCCACACATACATCATGATTCCGGGAACGGATGTTAAGTTTGAATTAGGTTGGGCGTATTTCGTACTTGTACTA
TTTATGCTTATTGGTGGATCAAATGCAGTTAACTTAACTGACGGTTTAGATGGTTTATTATCAGGAACAGCTGCTATTGC
ATTTGGAGCATTTAGTATTATTGCTGTGGCACAAGAGCAATTTGGAGTAGCGATATTCTGTATGGCAGTTGTAGGAGCTG
TACTTGGATTTTTAGTATTCAATGCGAATCCAGCAAAAGTGTTTATGGGAGATACAGGTTCATTAGCTTTAGGTGGAGCC
ATTGCAGCTGTAGCGATTTTATTAAAACAAGAATTGCTACTTGTAATTATTGGCGGAGTATTCGTAATGGAAACTTTATC
GGTTATCATTCAGGTCATTTCATTTAAAACAACAGGAAAACGTGTCTTTAAAATGAGTCCATTACACCATCATTATGAAT
TATGTGGTTGGTCAGAGTGGCGTGTTGTTGTGACGTTTTGGTCTGCAGGATTTTTATTAGCTGTGTTAGGAATTTATATC
GGGGTGTGGATGTAA

Upstream 100 bases:

>100_bases
GGTAAAGAAGTTCATCATTTCGATGATCGTGAAGTTGCTAAAGAAGCAATTACAGGGCGTTTAAACAACGAAGAGTAACA
ACGTGAGAGGAGGACTACAT

Downstream 100 bases:

>100_bases
TTGAAAACTGTAACTGAATTTCAAAATAAGAATATTCTTGTATTGGGCATTGCAAAAAGTGGTTATGCAGCAGCTACATT
GTTACAAAAGCTAGGGGCAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNYLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSAGFLLAVLGIYI
GVWM

Sequences:

>Translated_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNYLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSAGFLLAVLGIYI
GVWM
>Mature_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNYLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSAGFLLAVLGIYI
GVWM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=326, Percent_Identity=47.5460122699387, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790218, Length=206, Percent_Identity=31.0679611650485, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34904; Mature: 34904

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTSLIMAIKFNYLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCC
RVVVTFWSAGFLLAVLGIYIGVWM
EEEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTSLIMAIKFNYLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVIAIAFFLIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCC
RVVVTFWSAGFLLAVLGIYIGVWM
EEEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA