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The map label for this gene is ywqM [H]

Identifier: 218231867

GI number: 218231867

Start: 3360486

End: 3361379

Strand: Reverse

Name: ywqM [H]

Synonym: BCB4264_A3482

Alternate gene names: 218231867

Gene position: 3361379-3360486 (Counterclockwise)

Preceding gene: 218233372

Following gene: 218231274

Centisome position: 62.03

GC content: 35.46

Gene sequence:

>894_bases
ATGGAAATAAAACAGTTAATTACATTTAAAGTAGCGGCAGATACTTTGAACTTTACACAAACTGCGAAGAAATTAAACTT
TGCTCAATCGAGCGTGACAGCGCAAATTAAAACGTTAGAAGCTGAGCTTGGTACACCGTTATTTGAAAGATTAGGAAAAC
GTCTTTTCTTAACTGAAGCAGGTAGGAAGTTTCAACTATATGCCGACAAGATGATTGCACTCAGTAACGAAGCGAAAATG
GCTGTGAAAGATGATGAAGAAATAGCAGGTACGTTAATAATTGGTGCACAAGAAAGTCAATGTACCTACAGACTGCCTTC
TATATTAAAGAGGTTTAAAATACAATTCCCAAAAATAAAACTTATATTTAAACCAGCACATTCCAATAAAGATGCGAAGG
AACAATTGATGGAGGGAAAAGTAGATCTTGCATTTATTTTGGATGAGTGTAAAACAGAAGATGTTTTACATGTGGAACCA
CTTATGAAAGAAGAATTAAAAGTAGTAGCTGCTCCAGGGCATCGTTTACTTGAACAACCTTCAGTTTCTATAAAAGATTT
AGAGAGTGAAACACTTTTACTAACAGAATTAGGCTGCTCGTATCGGACTTTATTTGAAGAGCTATTTCGCGGGGAAGATG
TATATCCAGCAAATAAAATTGAGTTTGTTAGTGTTGAAGCAATTAAACAATGTGTTATTGCAGATTTAGGCATAGCCGTT
TTACCAGCAATAGTAGTAGAAAAAGATATACGAGAGGGGACGATAAAAGAGTTACATTTAGAAAATACAATCTCTCCGAT
TTATACGCAAATCGCTTGGCATAAAGACAAATGGATGACAGTGCCACTGCGCCAATTTATTGATGTAACGAGGGAGTTTT
TTGTAACGGATTAA

Upstream 100 bases:

>100_bases
TTTATAGATGTTCTTTATCATACAATACAAATATCAATAGACAAAGAGGATTATTTCGATGGAATCAATCGGAAATATCG
ATTGAAAAGAGGGATGATAA

Downstream 100 bases:

>100_bases
GTGGAGAAATATTTATTTTATATAAAAGAAAAAATGGCAATTTTGTATAAAGAACCGATGCTTGAATATAACAAGTATCG
GTTCTTTTATGTTTTAAATA

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MEIKQLITFKVAADTLNFTQTAKKLNFAQSSVTAQIKTLEAELGTPLFERLGKRLFLTEAGRKFQLYADKMIALSNEAKM
AVKDDEEIAGTLIIGAQESQCTYRLPSILKRFKIQFPKIKLIFKPAHSNKDAKEQLMEGKVDLAFILDECKTEDVLHVEP
LMKEELKVVAAPGHRLLEQPSVSIKDLESETLLLTELGCSYRTLFEELFRGEDVYPANKIEFVSVEAIKQCVIADLGIAV
LPAIVVEKDIREGTIKELHLENTISPIYTQIAWHKDKWMTVPLRQFIDVTREFFVTD

Sequences:

>Translated_297_residues
MEIKQLITFKVAADTLNFTQTAKKLNFAQSSVTAQIKTLEAELGTPLFERLGKRLFLTEAGRKFQLYADKMIALSNEAKM
AVKDDEEIAGTLIIGAQESQCTYRLPSILKRFKIQFPKIKLIFKPAHSNKDAKEQLMEGKVDLAFILDECKTEDVLHVEP
LMKEELKVVAAPGHRLLEQPSVSIKDLESETLLLTELGCSYRTLFEELFRGEDVYPANKIEFVSVEAIKQCVIADLGIAV
LPAIVVEKDIREGTIKELHLENTISPIYTQIAWHKDKWMTVPLRQFIDVTREFFVTD
>Mature_297_residues
MEIKQLITFKVAADTLNFTQTAKKLNFAQSSVTAQIKTLEAELGTPLFERLGKRLFLTEAGRKFQLYADKMIALSNEAKM
AVKDDEEIAGTLIIGAQESQCTYRLPSILKRFKIQFPKIKLIFKPAHSNKDAKEQLMEGKVDLAFILDECKTEDVLHVEP
LMKEELKVVAAPGHRLLEQPSVSIKDLESETLLLTELGCSYRTLFEELFRGEDVYPANKIEFVSVEAIKQCVIADLGIAV
LPAIVVEKDIREGTIKELHLENTISPIYTQIAWHKDKWMTVPLRQFIDVTREFFVTD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082132, Length=297, Percent_Identity=27.6094276094276, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787806, Length=289, Percent_Identity=29.757785467128, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=28.3737024221453, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=23.3676975945017, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787530, Length=296, Percent_Identity=23.9864864864865, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790399, Length=264, Percent_Identity=28.030303030303, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=24.5733788395904, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=26.5625, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=24.8299319727891, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=24.5901639344262, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=25.752508361204, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788706, Length=257, Percent_Identity=24.5136186770428, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=25.2, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788748, Length=247, Percent_Identity=21.0526315789474, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=249, Percent_Identity=23.2931726907631, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=26.4822134387352, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788626, Length=253, Percent_Identity=25.296442687747, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33733; Mature: 33733

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKQLITFKVAADTLNFTQTAKKLNFAQSSVTAQIKTLEAELGTPLFERLGKRLFLTEA
CCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECC
GRKFQLYADKMIALSNEAKMAVKDDEEIAGTLIIGAQESQCTYRLPSILKRFKIQFPKIK
CCEEEEEHHHHEEECCCCCEEECCCCHHEEEEEEECCCCCCEEHHHHHHHHHCCCCCEEE
LIFKPAHSNKDAKEQLMEGKVDLAFILDECKTEDVLHVEPLMKEELKVVAAPGHRLLEQP
EEEECCCCCCHHHHHHHCCCCHHEEEEHHHCCCCEEECCHHHHHHHEEEECCCHHHHCCC
SVSIKDLESETLLLTELGCSYRTLFEELFRGEDVYPANKIEFVSVEAIKQCVIADLGIAV
CCCCCCCCCCEEEEEHHCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
LPAIVVEKDIREGTIKELHLENTISPIYTQIAWHKDKWMTVPLRQFIDVTREFFVTD
HHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIKQLITFKVAADTLNFTQTAKKLNFAQSSVTAQIKTLEAELGTPLFERLGKRLFLTEA
CCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECC
GRKFQLYADKMIALSNEAKMAVKDDEEIAGTLIIGAQESQCTYRLPSILKRFKIQFPKIK
CCEEEEEHHHHEEECCCCCEEECCCCHHEEEEEEECCCCCCEEHHHHHHHHHCCCCCEEE
LIFKPAHSNKDAKEQLMEGKVDLAFILDECKTEDVLHVEPLMKEELKVVAAPGHRLLEQP
EEEECCCCCCHHHHHHHCCCCHHEEEEHHHCCCCEEECCHHHHHHHEEEECCCHHHHCCC
SVSIKDLESETLLLTELGCSYRTLFEELFRGEDVYPANKIEFVSVEAIKQCVIADLGIAV
CCCCCCCCCCEEEEEHHCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
LPAIVVEKDIREGTIKELHLENTISPIYTQIAWHKDKWMTVPLRQFIDVTREFFVTD
HHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]