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The map label for this gene is hblA [H]

Identifier: 218231853

GI number: 218231853

Start: 2998496

End: 2999623

Strand: Reverse

Name: hblA [H]

Synonym: BCB4264_A3124

Alternate gene names: 218231853

Gene position: 2999623-2998496 (Counterclockwise)

Preceding gene: 218231407

Following gene: 218232691

Centisome position: 55.35

GC content: 34.22

Gene sequence:

>1128_bases
ATGATAAAAAAAATCCCTTACAAATTACTCGCTGTATCGACGCTATTAACTATTACAACCGCTAATGTAGTTTCACCAGT
AACAACTTTTGCAAGTGAAATTGAACAAACGAATAATGGAGATACGGCTCTTTCTGCAAATGAAGCGAGAATGAAAGAGA
CCTTGCAAAAGGCTGGATTATTTGCAAAATCTATGAATGCCTATTCTTATATGTTAATTAAGAATCCTGATGTGAATTTT
GAGGGAATTACCATTAATGGATATGTAGATTTACCTGGTAGAATCGTACAAGATCAAAAGAATGCAAGGGCACATGCCGT
TACTTGGGATACGAAAGTAAAAAAACAGCTTTTAGATACACTGAATGGTATTGTTGAATACGATACAACATTTGATAATT
ATTATGAAACAATGATAGAGGCGATTAATACAGGGGATGGAGAAACTTTAAAAGAAGGGATTACAGATTTACGAGGTGAA
ATTCAACAAAATCAAAAGTATGCACAACAACTAATAGAAGAATTAACTAAATTAAGAGACTCTATTGGACACGATGTTAG
AGCATTTGGAAGTAATAAAGAGCTCTTGCAGTCAATTTTAAAAAATCAAGGTGCAGATGTTGATGCCGATCAAAAGCGTC
TAGAAGAAGTATTAGGATCAGTAAACTATTATAAACAATTAGAATCTGATGGGTTTAATGTAATGAAGGGTGCTATTTTG
GGTCTACCAATAATTGGCGGTATCATAGTGGGAGTAGCAAGGGATAATTTAGGTAAGTTAGAGCCTTTATTAGCAGAATT
ACGTCAGACCGTGGATTATAAAGTAACCTTAAATCGTGTAGTTGGAGTTGCTTACAGTAATATTAATGAAATGCACAAGG
CGCTTGATGATGCTATTAACGCTCTTACTTATATGTCCACGCAGTGGCATGATTTAGATTCTCAATATTCGGGCGTTCTA
GGGCATATTGAGAATGCAGCTCAAAAAGCCGATCAAAATAAATTTAAATTCTTAAAACCTAATTTAAATGCAGCGAAAGA
CAGTTGGAAAACATTACGAACAGATGCTGTTACATTAAAAGAAGGAATAAAGGAATTAAAAGTGGAAACTGTCACTCCAC
AAAAATAG

Upstream 100 bases:

>100_bases
TTGGAATGATATTCATAAAGATGCAGAATTCATTTCAAAAGATATTGCTTTTAAACAGGAGTAGAACTGAAATTAAAAAC
CTAAATTGGAGGAAAATGAA

Downstream 100 bases:

>100_bases
GGAAATATTAATTCTGTTGTAAAGTGAACTAAAACATAGAAAGTCTATGATTACACTGTTAAACAGAAAAGTAATAATTA
ATAAATCCTTATATAACAGA

Product: Hbl B protein

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNGDTALSANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNF
EGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLNGIVEYDTTFDNYYETMIEAINTGDGETLKEGITDLRGE
IQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQYSGVL
GHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK

Sequences:

>Translated_375_residues
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNGDTALSANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNF
EGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLNGIVEYDTTFDNYYETMIEAINTGDGETLKEGITDLRGE
IQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQYSGVL
GHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK
>Mature_375_residues
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNGDTALSANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNF
EGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLNGIVEYDTTFDNYYETMIEAINTGDGETLKEGITDLRGE
IQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQYSGVL
GHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 41693; Mature: 41693

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNGDTALSANEARMKETLQKAGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHH
FAKSMNAYSYMLIKNPDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDT
HHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHCCCCCCCEEEEECHHHHHHHHHHH
LNGIVEYDTTFDNYYETMIEAINTGDGETLKEGITDLRGEIQQNQKYAQQLIEELTKLRD
HHHHEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
HHCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAIN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
ALTYMSTQWHDLDSQYSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLK
HHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
EGIKELKVETVTPQK
HHHHHHEECCCCCCC
>Mature Secondary Structure
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNGDTALSANEARMKETLQKAGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHH
FAKSMNAYSYMLIKNPDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDT
HHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHCCCCCCCEEEEECHHHHHHHHHHH
LNGIVEYDTTFDNYYETMIEAINTGDGETLKEGITDLRGEIQQNQKYAQQLIEELTKLRD
HHHHEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
HHCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAIN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
ALTYMSTQWHDLDSQYSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLK
HHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
EGIKELKVETVTPQK
HHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]