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The map label for this gene is mcrB [C]

Identifier: 218231808

GI number: 218231808

Start: 945377

End: 947911

Strand: Direct

Name: mcrB [C]

Synonym: BCB4264_A0970

Alternate gene names: 218231808

Gene position: 945377-947911 (Clockwise)

Preceding gene: 218235715

Following gene: 218231211

Centisome position: 17.45

GC content: 34.12

Gene sequence:

>2535_bases
ATGTTAGAGCAACTCATAATGGAATTAGCTAAGTCAATAAAGCAGGTTGAAGATATAAATGGTGATAAAACTTATTTGGT
TATAAACAAAGATGATGGAGACTTAGACATTGAAATCAAATTTTTACGTGAGCAATATGAAGAGAAAGTATCATCTTATT
TTAAAGTAAGGTCTGAGCTCCTTAAGAACGCTTGGAAAAAATTTATCGATATGCGTACGGTAAAGAGTGAAGATTTCGGA
CAAGTGAGTGAATGTAATACTTTCTTAGTAGCATTCTTTTCACACCTTCCATTTGTGGATGTAAGGGAATCGGGGGCTAT
TACATTTAAAGAGTTCCAAACTGATAATTTACCATGTGAGCAGTATCATAAAGTTGTTGGATTTTTGGAAGAGGTAATAA
ACGATACGTACGATCCGAAAAATTTAAGTGATCATATTAGTGGTAATTTGTATAGAGTTAAATCTAAAGGAAGACAAGAT
TTAAGGTTACTGGGATTTTTAAATGATAATCATGATATTGATACGTCTTTATTAAATGAATACATTGGAGAAAAGAGTAA
GAATGATGTTATTCGAAAGCTAGTTTTAAAGCAGGAGTATTTTCAAATTGCTCTGTTTGTACTTAATCTTTTAAGAGTGT
ATCCGAGGGCTGCCAAGAAGGCTACTTTAGTGGATTTAGCGATGACAATCGTCCGAAACTCTAGAGGAGATAATTTAATG
CTAGAATCATTAGCGAAAGAGCGTACGCATAATCTCTTAATGTGGTCTGAGAAATTGGAAATAATTAATGCTGAATGGAT
TCCAGCCGAACAATACATAAAAAAGAGTGAAGAAAAGGGCGGTAATATGAGTAGTAGTTTACGTGAAGGCTTTTTAAAGA
TACTGAAAGAATATTTGGATGCAAAAACAGAAAAATTTGCAGGACATAAATTAGGATTAACAGTCCGAAATGATATAGCA
ACAGAGATCATTCGTTTACCATTTATAAATGAGAAGCAGTACAGTGTGATAGGGTCAGTCGGAAAAGGGAATTGGGCGAC
AGTTCCATGGATTGCACTAATGCATAGAAGTATTACAACATCGACACAGAGAGGGTATTATATCGTCTATTTATTTAGTG
AAGATATGCAACGATTGTATTTGACCATTGGACAAGGTGTGACAGAAACAACTAAAGAAGAGATGCAAAAAATTAAAGAA
GAGATTCGTGAACAAATACATATGTCCCAAAAGGTGAAAAAAGATGATGAGATTTTCCTAGGTACAAGCCCAAAAGCAAA
AGGATATGCAAATTCAACAGCAGCTTATATTGCGTATGATGCTAATAAAATGCCAAGCGAAAAAGAGTTAGTAGAGGACC
TAGAAGAAATGTTTCGTTATTATGAGGGATTCATAGCTTATAAAGAGAAAGGAACGAAATATGAAATGATCTATGAGAGG
AAAGAAGTCTATTTAGATCAGCAATCAATTATCGAGCATGTGTCTTCCTATATTCAAAGTAAAGGTTTCTTTTATGAGAA
AAAGGATCTTATTAACTTCTTCCTTTCATTAAAGACTAAGCCGTTTGTGATTTTATCAGGTATTTCAGGTACAGGGAAAA
CGAAAATTGTTCAGTGGTTTGCGGAAAGTTTAGGAGCAATGGAAGAGAATGGACAATTTACACTTATTCCGGTTCGACCT
GATTGGAGTGATAGTTCTGATTTGCTTGGTTATGTGAACCTTCAAGGGGAGTTTCAAGAAAGACCGTTAATTAAAGTTCT
TGAAAATGCAGATGCAAACCCAAATAGGCCGTATTTTGTAGTGTTGGATGAGATGAATTTAGCGCGAGTGGAATACTATT
TTAGTGATTTTTTAAGTGTAATTGAAAGCCGTAAATGGAAAGATGGAAAAATTGTTACGTCACCAGTGCTTCCAGAATCC
ATTACGAATAAGCACATTACGATCCCAGCAAATGTATATATTATCGGAACGGTAAACATGGACGAAACGACACATCCTTT
AAGTAAGAAAGTATTAGATCGTGCGAATACAATTGAGTTTAATACCGTTAACTTAGATTATTTTAATTTCTTAATGGATA
TAGAAGAGAAGGAAGCTGAAGTTGTTTCTAATAGCTCTTTAGCAACCGAGTATCTTCATTTAAAAGAATGCTTTAAAGAA
AATGAAGACCTTGTGAGAAATATATCGACTATTTTAATAGAAATAAATAAATCACTGGAATCAGTTGGGGCTCAAGTTGG
ATATCGTATACGAGATGAAATTTGTTTCTATATGGCATACAACGAAAAAGGAAAGTTATTATCGTTTGATGAAGCACTTG
ATTATCAAATATATCAAAAGATTTTACCACGTCTTGCAGGTAGCGACGGAAGAACAGAAGAGGTATTAAAGCAGTTGTAT
ATATTATGTGCAAATGAGGAATATGATAGTGGCAACAATGATGCTTCATATGCTAAATATCCTCGTTCTGCTAACAAGCT
GTCTCATATGTTAAGGAGGTTCGAGTATGATGGTTTCACCTCTTTCTGGATCTAA

Upstream 100 bases:

>100_bases
TAGAGGATGAAACGTACCTATGTATAAAAGATTACTTTCTTTTATACATAGTTTGGTAAAATAGTAGTAATTGTAATTAA
TTGTAACGGTGGGGATGAAA

Downstream 100 bases:

>100_bases
TAATGAGATAGAGCTAGTTAAGATTGAAACAGAGGAGCTATCATTGACGATTAAAGGGAATCCTTATCATGAAAAATATG
AGAGTTTAAAAGAATATCAC

Product: ATPase, AAA family

Products: NA

Alternate protein names: GTPase Subunit Of Restriction Endonuclease-Like Protein; 5-Methylcytosine-Specific Restriction ; GTPase Subunit Of Restriction Endonuclease-Like; Site-Specific DNA-Methyltransferase Cytosine-Specific; 5-Methylcytosine-Specific Restriction McrB Related Protein; AAA Family ATPase; Restriction Endonuclease; AAA ATPase; 5-Methylcytosine-Specific Restriction-Like Protein; Chromosome Segregation ATPase-Like Protein; ATPase AAA Family

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MLEQLIMELAKSIKQVEDINGDKTYLVINKDDGDLDIEIKFLREQYEEKVSSYFKVRSELLKNAWKKFIDMRTVKSEDFG
QVSECNTFLVAFFSHLPFVDVRESGAITFKEFQTDNLPCEQYHKVVGFLEEVINDTYDPKNLSDHISGNLYRVKSKGRQD
LRLLGFLNDNHDIDTSLLNEYIGEKSKNDVIRKLVLKQEYFQIALFVLNLLRVYPRAAKKATLVDLAMTIVRNSRGDNLM
LESLAKERTHNLLMWSEKLEIINAEWIPAEQYIKKSEEKGGNMSSSLREGFLKILKEYLDAKTEKFAGHKLGLTVRNDIA
TEIIRLPFINEKQYSVIGSVGKGNWATVPWIALMHRSITTSTQRGYYIVYLFSEDMQRLYLTIGQGVTETTKEEMQKIKE
EIREQIHMSQKVKKDDEIFLGTSPKAKGYANSTAAYIAYDANKMPSEKELVEDLEEMFRYYEGFIAYKEKGTKYEMIYER
KEVYLDQQSIIEHVSSYIQSKGFFYEKKDLINFFLSLKTKPFVILSGISGTGKTKIVQWFAESLGAMEENGQFTLIPVRP
DWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFVVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPES
ITNKHITIPANVYIIGTVNMDETTHPLSKKVLDRANTIEFNTVNLDYFNFLMDIEEKEAEVVSNSSLATEYLHLKECFKE
NEDLVRNISTILIEINKSLESVGAQVGYRIRDEICFYMAYNEKGKLLSFDEALDYQIYQKILPRLAGSDGRTEEVLKQLY
ILCANEEYDSGNNDASYAKYPRSANKLSHMLRRFEYDGFTSFWI

Sequences:

>Translated_844_residues
MLEQLIMELAKSIKQVEDINGDKTYLVINKDDGDLDIEIKFLREQYEEKVSSYFKVRSELLKNAWKKFIDMRTVKSEDFG
QVSECNTFLVAFFSHLPFVDVRESGAITFKEFQTDNLPCEQYHKVVGFLEEVINDTYDPKNLSDHISGNLYRVKSKGRQD
LRLLGFLNDNHDIDTSLLNEYIGEKSKNDVIRKLVLKQEYFQIALFVLNLLRVYPRAAKKATLVDLAMTIVRNSRGDNLM
LESLAKERTHNLLMWSEKLEIINAEWIPAEQYIKKSEEKGGNMSSSLREGFLKILKEYLDAKTEKFAGHKLGLTVRNDIA
TEIIRLPFINEKQYSVIGSVGKGNWATVPWIALMHRSITTSTQRGYYIVYLFSEDMQRLYLTIGQGVTETTKEEMQKIKE
EIREQIHMSQKVKKDDEIFLGTSPKAKGYANSTAAYIAYDANKMPSEKELVEDLEEMFRYYEGFIAYKEKGTKYEMIYER
KEVYLDQQSIIEHVSSYIQSKGFFYEKKDLINFFLSLKTKPFVILSGISGTGKTKIVQWFAESLGAMEENGQFTLIPVRP
DWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFVVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPES
ITNKHITIPANVYIIGTVNMDETTHPLSKKVLDRANTIEFNTVNLDYFNFLMDIEEKEAEVVSNSSLATEYLHLKECFKE
NEDLVRNISTILIEINKSLESVGAQVGYRIRDEICFYMAYNEKGKLLSFDEALDYQIYQKILPRLAGSDGRTEEVLKQLY
ILCANEEYDSGNNDASYAKYPRSANKLSHMLRRFEYDGFTSFWI
>Mature_844_residues
MLEQLIMELAKSIKQVEDINGDKTYLVINKDDGDLDIEIKFLREQYEEKVSSYFKVRSELLKNAWKKFIDMRTVKSEDFG
QVSECNTFLVAFFSHLPFVDVRESGAITFKEFQTDNLPCEQYHKVVGFLEEVINDTYDPKNLSDHISGNLYRVKSKGRQD
LRLLGFLNDNHDIDTSLLNEYIGEKSKNDVIRKLVLKQEYFQIALFVLNLLRVYPRAAKKATLVDLAMTIVRNSRGDNLM
LESLAKERTHNLLMWSEKLEIINAEWIPAEQYIKKSEEKGGNMSSSLREGFLKILKEYLDAKTEKFAGHKLGLTVRNDIA
TEIIRLPFINEKQYSVIGSVGKGNWATVPWIALMHRSITTSTQRGYYIVYLFSEDMQRLYLTIGQGVTETTKEEMQKIKE
EIREQIHMSQKVKKDDEIFLGTSPKAKGYANSTAAYIAYDANKMPSEKELVEDLEEMFRYYEGFIAYKEKGTKYEMIYER
KEVYLDQQSIIEHVSSYIQSKGFFYEKKDLINFFLSLKTKPFVILSGISGTGKTKIVQWFAESLGAMEENGQFTLIPVRP
DWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFVVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPES
ITNKHITIPANVYIIGTVNMDETTHPLSKKVLDRANTIEFNTVNLDYFNFLMDIEEKEAEVVSNSSLATEYLHLKECFKE
NEDLVRNISTILIEINKSLESVGAQVGYRIRDEICFYMAYNEKGKLLSFDEALDYQIYQKILPRLAGSDGRTEEVLKQLY
ILCANEEYDSGNNDASYAKYPRSANKLSHMLRRFEYDGFTSFWI

Specific function: Recognizes N4- And C5-Methylcytosine (And 5-Hydroxy- Methylcytosines) Produced By A Broad Range Of DNA Methylases And Appears To Act Against 5-Methylcytosine Preceded By A Purine Residue. Binds To DNA Containing Methylated Cytosines; Also Binds To GTP. [

COG id: COG1401

COG function: function code V; GTPase subunit of restriction endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.21.- [C]

Molecular weight: Translated: 97738; Mature: 97738

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQLIMELAKSIKQVEDINGDKTYLVINKDDGDLDIEIKFLREQYEEKVSSYFKVRSEL
CHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
LKNAWKKFIDMRTVKSEDFGQVSECNTFLVAFFSHLPFVDVRESGAITFKEFQTDNLPCE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCCCCHH
QYHKVVGFLEEVINDTYDPKNLSDHISGNLYRVKSKGRQDLRLLGFLNDNHDIDTSLLNE
HHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHH
YIGEKSKNDVIRKLVLKQEYFQIALFVLNLLRVYPRAAKKATLVDLAMTIVRNSRGDNLM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LESLAKERTHNLLMWSEKLEIINAEWIPAEQYIKKSEEKGGNMSSSLREGFLKILKEYLD
HHHHHHHHHCCCEEEECHHHEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
AKTEKFAGHKLGLTVRNDIATEIIRLPFINEKQYSVIGSVGKGNWATVPWIALMHRSITT
CHHHHHCCCEECEEEHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHHCC
STQRGYYIVYLFSEDMQRLYLTIGQGVTETTKEEMQKIKEEIREQIHMSQKVKKDDEIFL
CCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GTSPKAKGYANSTAAYIAYDANKMPSEKELVEDLEEMFRYYEGFIAYKEKGTKYEMIYER
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEHHHHHH
KEVYLDQQSIIEHVSSYIQSKGFFYEKKDLINFFLSLKTKPFVILSGISGTGKTKIVQWF
HHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AESLGAMEENGQFTLIPVRPDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFV
HHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEE
VLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPESITNKHITIPANVYIIGTVNM
EEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHCCCEEEECCEEEEEEEECC
DETTHPLSKKVLDRANTIEFNTVNLDYFNFLMDIEEKEAEVVSNSSLATEYLHLKECFKE
CCCCCHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
NEDLVRNISTILIEINKSLESVGAQVGYRIRDEICFYMAYNEKGKLLSFDEALDYQIYQK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEECCCCCEEEHHHHHHHHHHHH
ILPRLAGSDGRTEEVLKQLYILCANEEYDSGNNDASYAKYPRSANKLSHMLRRFEYDGFT
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCE
SFWI
ECCC
>Mature Secondary Structure
MLEQLIMELAKSIKQVEDINGDKTYLVINKDDGDLDIEIKFLREQYEEKVSSYFKVRSEL
CHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
LKNAWKKFIDMRTVKSEDFGQVSECNTFLVAFFSHLPFVDVRESGAITFKEFQTDNLPCE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCCCCHH
QYHKVVGFLEEVINDTYDPKNLSDHISGNLYRVKSKGRQDLRLLGFLNDNHDIDTSLLNE
HHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHH
YIGEKSKNDVIRKLVLKQEYFQIALFVLNLLRVYPRAAKKATLVDLAMTIVRNSRGDNLM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LESLAKERTHNLLMWSEKLEIINAEWIPAEQYIKKSEEKGGNMSSSLREGFLKILKEYLD
HHHHHHHHHCCCEEEECHHHEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
AKTEKFAGHKLGLTVRNDIATEIIRLPFINEKQYSVIGSVGKGNWATVPWIALMHRSITT
CHHHHHCCCEECEEEHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHHCC
STQRGYYIVYLFSEDMQRLYLTIGQGVTETTKEEMQKIKEEIREQIHMSQKVKKDDEIFL
CCCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GTSPKAKGYANSTAAYIAYDANKMPSEKELVEDLEEMFRYYEGFIAYKEKGTKYEMIYER
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEHHHHHH
KEVYLDQQSIIEHVSSYIQSKGFFYEKKDLINFFLSLKTKPFVILSGISGTGKTKIVQWF
HHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AESLGAMEENGQFTLIPVRPDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFV
HHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEE
VLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPESITNKHITIPANVYIIGTVNM
EEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHCCCEEEECCEEEEEEEECC
DETTHPLSKKVLDRANTIEFNTVNLDYFNFLMDIEEKEAEVVSNSSLATEYLHLKECFKE
CCCCCHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
NEDLVRNISTILIEINKSLESVGAQVGYRIRDEICFYMAYNEKGKLLSFDEALDYQIYQK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEECCCCCEEEHHHHHHHHHHHH
ILPRLAGSDGRTEEVLKQLYILCANEEYDSGNNDASYAKYPRSANKLSHMLRRFEYDGFT
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCE
SFWI
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Endodeoxyribonucleases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA