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The map label for this gene is adhR [H]

Identifier: 218231639

GI number: 218231639

Start: 851377

End: 851736

Strand: Direct

Name: adhR [H]

Synonym: BCB4264_A0886

Alternate gene names: 218231639

Gene position: 851377-851736 (Clockwise)

Preceding gene: 218232868

Following gene: 218233715

Centisome position: 15.71

GC content: 33.06

Gene sequence:

>360_bases
ATGTACACAATTAGCGAGGTAGCAAAATTATTAGGCGTGAGCACACATACACTACGTTATTATGAAAAGGAAAATATATT
AATTGCAAATCGAGATACAAATGGAAATCGACTTTACGAAGAGTCACATATAAAGTGGTTGCAGTTTGTAATGAAATTAA
AACAAACGCAAATGCCAATAGCGAAAATAAGAGAATACGCTAGATTATATACAGAAGGGGAGCATACAACAGAAGCTCGT
TTACAGCTCCTAGAAGATCATAGGAAATCTATTCAGATTCAAAGAGAAAACTTAGAAGTTACAGAGAAGATGCTTGAGAA
TAAAATTCGTACATACAAAAGCTCATTGGAAAATAAATAG

Upstream 100 bases:

>100_bases
TAGATTGTATTTGTTAGAGTATACTCTAAGTCAAATGTTTTTTATAAATTTGATAAGGTCATAAAATATATGAGGGTAAG
CATGTGGAGGGAGTTTTAGT

Downstream 100 bases:

>100_bases
ATGTTGTTATGTGATGAAAAATGGATTTGATCTATGAGTATTTCATCATAGTGTGCGGATAAATAAAAAAGAGCAGCTAG
CAAAAGCTAACTGCTCCATT

Product: mercuric resistance operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MYTISEVAKLLGVSTHTLRYYEKENILIANRDTNGNRLYEESHIKWLQFVMKLKQTQMPIAKIREYARLYTEGEHTTEAR
LQLLEDHRKSIQIQRENLEVTEKMLENKIRTYKSSLENK

Sequences:

>Translated_119_residues
MYTISEVAKLLGVSTHTLRYYEKENILIANRDTNGNRLYEESHIKWLQFVMKLKQTQMPIAKIREYARLYTEGEHTTEAR
LQLLEDHRKSIQIQRENLEVTEKMLENKIRTYKSSLENK
>Mature_119_residues
MYTISEVAKLLGVSTHTLRYYEKENILIANRDTNGNRLYEESHIKWLQFVMKLKQTQMPIAKIREYARLYTEGEHTTEAR
LQLLEDHRKSIQIQRENLEVTEKMLENKIRTYKSSLENK

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14274; Mature: 14274

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTISEVAKLLGVSTHTLRYYEKENILIANRDTNGNRLYEESHIKWLQFVMKLKQTQMPI
CCCHHHHHHHHCCCHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AKIREYARLYTEGEHTTEARLQLLEDHRKSIQIQRENLEVTEKMLENKIRTYKSSLENK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYTISEVAKLLGVSTHTLRYYEKENILIANRDTNGNRLYEESHIKWLQFVMKLKQTQMPI
CCCHHHHHHHHCCCHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AKIREYARLYTEGEHTTEARLQLLEDHRKSIQIQRENLEVTEKMLENKIRTYKSSLENK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]