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The map label for this gene is fabH2 [H]

Identifier: 218231606

GI number: 218231606

Start: 1738690

End: 1739673

Strand: Reverse

Name: fabH2 [H]

Synonym: BCB4264_A1833

Alternate gene names: 218231606

Gene position: 1739673-1738690 (Counterclockwise)

Preceding gene: 218231671

Following gene: 218234230

Centisome position: 32.1

GC content: 35.77

Gene sequence:

>984_bases
ATGCATTCTAAATCTCGTATTACTGCAATCGGTACTTATGTTCCAGATCAAATATTGTCTAATAACGATTTAGAAAAGAT
GGTCCATACGAATGATGAATGGATTGTACAAAGAACAGGAATGAAGGAAAGAAGAATCGCTAGTGACGAAGAATACTCCT
CAAACTTAGCCATTAAAGCAATTAAAAATTTATGTACAACATATAAGAAAAACTTAGAAGATGTCGACTGTATCATTGTC
GCTACTACTACTGCTGATTACATTTTCCCTAGTGTTGCTTGCCAAATACAACAATACTTCAACATACCTCATACACTAGC
TTTTGATTTAAATGCAACTTGTGCTGGTTTTACATATGGACTACACGTCGGTAATAGCTTAATCACTTCTGGATCACATG
AAAAAGTACTTGTCGTAGCGACAGAGACATTATCTAAAGTTACTGATTATACCGATAGAACGACCTGTATTTTATTCGGT
GATGGTGCTGGAGCTATTTTATTAGAAAGAGATGAAAACACCCCAAGCTTTATCGCTGCTCACATGGGAACAAACGGTGA
TGGCGGCATTCATCTATATAGAACAAACTTATCTACTACTATGAATGGCACACCACTGCAAACAAATGAAAAAATCGTTC
AAAATGGAAGAGAAGTATATAAATGGGCAACACGCACAGTACCAAAAGGCATAAAAAATTTATTACATACCGTAAATATG
CAAGTAGATGATATAGACTGGTTCATACCCCACAGCGCTAACTTACGAATGATCGAATCTATTTGCGAAAAATCTCAAAT
TCCAATACAAAAAACATTAACGAGCGTGGAATATATGGGGAATACCTCTTCAGTCACCATTCCACTCGCTTTAAATTTAG
CTATAAAAGAAGGGAACTTAAATAACGGAGACACACTTTTACTATACGGATTTGGTGGCGGACTTACGCATTTAGGGCTT
ATTGTAGAGTGGAATTTAATTTAA

Upstream 100 bases:

>100_bases
TTAAGTATTATCGTTTTAATACAACAAAAATCTTTATTGACATTTTTATAACCTAATATTAGTATCAGGTTATAAAAAAT
AAAAGTTAGGAGATGTTCCT

Downstream 100 bases:

>100_bases
GTGTATAAAAAGAGGTTCTAGTCAGTAACTAGAACCTCTTTTTCATTTAATTTCTTGCCCCTTTTCGAGACCATATCACA
ACAGGAATAAGTAATAACGC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MHSKSRITAIGTYVPDQILSNNDLEKMVHTNDEWIVQRTGMKERRIASDEEYSSNLAIKAIKNLCTTYKKNLEDVDCIIV
ATTTADYIFPSVACQIQQYFNIPHTLAFDLNATCAGFTYGLHVGNSLITSGSHEKVLVVATETLSKVTDYTDRTTCILFG
DGAGAILLERDENTPSFIAAHMGTNGDGGIHLYRTNLSTTMNGTPLQTNEKIVQNGREVYKWATRTVPKGIKNLLHTVNM
QVDDIDWFIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVTIPLALNLAIKEGNLNNGDTLLLYGFGGGLTHLGL
IVEWNLI

Sequences:

>Translated_327_residues
MHSKSRITAIGTYVPDQILSNNDLEKMVHTNDEWIVQRTGMKERRIASDEEYSSNLAIKAIKNLCTTYKKNLEDVDCIIV
ATTTADYIFPSVACQIQQYFNIPHTLAFDLNATCAGFTYGLHVGNSLITSGSHEKVLVVATETLSKVTDYTDRTTCILFG
DGAGAILLERDENTPSFIAAHMGTNGDGGIHLYRTNLSTTMNGTPLQTNEKIVQNGREVYKWATRTVPKGIKNLLHTVNM
QVDDIDWFIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVTIPLALNLAIKEGNLNNGDTLLLYGFGGGLTHLGL
IVEWNLI
>Mature_327_residues
MHSKSRITAIGTYVPDQILSNNDLEKMVHTNDEWIVQRTGMKERRIASDEEYSSNLAIKAIKNLCTTYKKNLEDVDCIIV
ATTTADYIFPSVACQIQQYFNIPHTLAFDLNATCAGFTYGLHVGNSLITSGSHEKVLVVATETLSKVTDYTDRTTCILFG
DGAGAILLERDENTPSFIAAHMGTNGDGGIHLYRTNLSTTMNGTPLQTNEKIVQNGREVYKWATRTVPKGIKNLLHTVNM
QVDDIDWFIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVTIPLALNLAIKEGNLNNGDTLLLYGFGGGLTHLGL
IVEWNLI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=314, Percent_Identity=37.8980891719745, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36133; Mature: 36133

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSKSRITAIGTYVPDQILSNNDLEKMVHTNDEWIVQRTGMKERRIASDEEYSSNLAIKA
CCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCEEEEECCCCHHHCCCCCHHCCCHHHHH
IKNLCTTYKKNLEDVDCIIVATTTADYIFPSVACQIQQYFNIPHTLAFDLNATCAGFTYG
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEE
LHVGNSLITSGSHEKVLVVATETLSKVTDYTDRTTCILFGDGAGAILLERDENTPSFIAA
EECCCHHCCCCCCCEEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
HMGTNGDGGIHLYRTNLSTTMNGTPLQTNEKIVQNGREVYKWATRTVPKGIKNLLHTVNM
ECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
QVDDIDWFIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVTIPLALNLAIKEGNL
EEECEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCC
NNGDTLLLYGFGGGLTHLGLIVEWNLI
CCCCEEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MHSKSRITAIGTYVPDQILSNNDLEKMVHTNDEWIVQRTGMKERRIASDEEYSSNLAIKA
CCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCEEEEECCCCHHHCCCCCHHCCCHHHHH
IKNLCTTYKKNLEDVDCIIVATTTADYIFPSVACQIQQYFNIPHTLAFDLNATCAGFTYG
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEE
LHVGNSLITSGSHEKVLVVATETLSKVTDYTDRTTCILFGDGAGAILLERDENTPSFIAA
EECCCHHCCCCCCCEEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
HMGTNGDGGIHLYRTNLSTTMNGTPLQTNEKIVQNGREVYKWATRTVPKGIKNLLHTVNM
ECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
QVDDIDWFIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVTIPLALNLAIKEGNL
EEECEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCC
NNGDTLLLYGFGGGLTHLGLIVEWNLI
CCCCEEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]