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The map label for this gene is murG [H]

Identifier: 218231507

GI number: 218231507

Start: 3757998

End: 3759062

Strand: Reverse

Name: murG [H]

Synonym: BCB4264_A3848

Alternate gene names: 218231507

Gene position: 3759062-3757998 (Counterclockwise)

Preceding gene: 218235895

Following gene: 218234125

Centisome position: 69.37

GC content: 34.08

Gene sequence:

>1065_bases
ATGAGCAAAACGATTCTTTTTACTGGGGGCGGTACAGCCGGACACGTTATGATTAATATTGTATTAATTCCTAAATTTAT
AGAGAAAGGCTGGAGAGTCGAGTATATTGGATCCAAAAATGGAATTGAAAAATCATTAGTGCAAAATGTTAAATACAATA
GTGTTTCAACGGGAAAGCTTAGGAGATATTGGGATTGGGAGAATTTTAAAGATCCTTTTAAAATTATACGCGGTTGTTTA
CAAAGTTATAATTTAATTAAGAAAACAAAGCCTGACGTTATCTTTTCAGCAGGAGGATTTGTTTCAGTTCCTGTAGCTAT
AGGAGCATGGTTAAATCGTGTGCCTATAATTATACGTGAACCAGATAGCACATTAGGGCTTGCCAATAAAATAGCATTAC
CTTTTGCTACAAAGCTATGCACAACATTTCCTCAGACAGGAGAAAATGTAAGTAATGAGAAGAAGGTTTATGTAGGACCA
ATTGTAAGGGAAGAAATTGAGAAGGGTAACGTATTACGAGGAAGAAGATATTGTGAATTTCAGCAAGATAAACCAGTATT
ATTAATTATGGGTGGGAGTCAAGGTGCTAAGTGGATAAATGATATGGTAAGGGAATGTGTAGATACAATACTATTAAACT
TTAATATTATTCATATATGTGGTAAAGGGAAGGTAGACCCATCTATTGGCATGGAGGGATATATGCAATTTGAATATATA
GGCGACGAGTTGCCGCATATACTAAATATGGCAAGTGTTGTAGTTTCTAGAGCGGGTTCTACTGCTATTTCTGAATTGTT
ATTTTTGAAGAAACCGATGTTGCTTATCCCGTTAACTAACAGTTCCAGTAGGGGAGATCAAGTTTTAAATGCTGAATATT
TTTCACGGCAAGGATATGCGGAAGTTATACTCCAAGACAGAGTAAGTACGAATACATTTATACATGCAGTAAATAAGTTG
TATACAAATAAGGAGAAATATATTCAAAACATGAATGGATATAAGAAAACAAATGATGAGGGAATTCATCAAATAATAGA
TATAATAAATGAAGTGGTGAAGTAA

Upstream 100 bases:

>100_bases
AGAGGTGGAGTTAAAGATTTGTATAAAAAATAATAAGTTTATTTACATTTAAAAGGTAAAGAGAAAGCTAGATTTTTAAT
AATAAAGGTGGGTATAGGTT

Downstream 100 bases:

>100_bases
TAGAAATGTAAATAGAAAAACAAAAGGAAAGAAGGTATCTTCTTTCCTTTTTGCTATATTTGTTCTAATTAGTTATGTAC
TATGGGTGAATGCCGTTTTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 3 [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSKTILFTGGGTAGHVMINIVLIPKFIEKGWRVEYIGSKNGIEKSLVQNVKYNSVSTGKLRRYWDWENFKDPFKIIRGCL
QSYNLIKKTKPDVIFSAGGFVSVPVAIGAWLNRVPIIIREPDSTLGLANKIALPFATKLCTTFPQTGENVSNEKKVYVGP
IVREEIEKGNVLRGRRYCEFQQDKPVLLIMGGSQGAKWINDMVRECVDTILLNFNIIHICGKGKVDPSIGMEGYMQFEYI
GDELPHILNMASVVVSRAGSTAISELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKL
YTNKEKYIQNMNGYKKTNDEGIHQIIDIINEVVK

Sequences:

>Translated_354_residues
MSKTILFTGGGTAGHVMINIVLIPKFIEKGWRVEYIGSKNGIEKSLVQNVKYNSVSTGKLRRYWDWENFKDPFKIIRGCL
QSYNLIKKTKPDVIFSAGGFVSVPVAIGAWLNRVPIIIREPDSTLGLANKIALPFATKLCTTFPQTGENVSNEKKVYVGP
IVREEIEKGNVLRGRRYCEFQQDKPVLLIMGGSQGAKWINDMVRECVDTILLNFNIIHICGKGKVDPSIGMEGYMQFEYI
GDELPHILNMASVVVSRAGSTAISELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKL
YTNKEKYIQNMNGYKKTNDEGIHQIIDIINEVVK
>Mature_353_residues
SKTILFTGGGTAGHVMINIVLIPKFIEKGWRVEYIGSKNGIEKSLVQNVKYNSVSTGKLRRYWDWENFKDPFKIIRGCLQ
SYNLIKKTKPDVIFSAGGFVSVPVAIGAWLNRVPIIIREPDSTLGLANKIALPFATKLCTTFPQTGENVSNEKKVYVGPI
VREEIEKGNVLRGRRYCEFQQDKPVLLIMGGSQGAKWINDMVRECVDTILLNFNIIHICGKGKVDPSIGMEGYMQFEYIG
DELPHILNMASVVVSRAGSTAISELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKLY
TNKEKYIQNMNGYKKTNDEGIHQIIDIINEVVK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=319, Percent_Identity=27.5862068965517, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39788; Mature: 39657

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTILFTGGGTAGHVMINIVLIPKFIEKGWRVEYIGSKNGIEKSLVQNVKYNSVSTGKL
CCCEEEEECCCCCCEEEEEEEEEEHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCH
RRYWDWENFKDPFKIIRGCLQSYNLIKKTKPDVIFSAGGFVSVPVAIGAWLNRVPIIIRE
HEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHCCCEEEEC
PDSTLGLANKIALPFATKLCTTFPQTGENVSNEKKVYVGPIVREEIEKGNVLRGRRYCEF
CCCHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHCCCEECCCCCCCC
QQDKPVLLIMGGSQGAKWINDMVRECVDTILLNFNIIHICGKGKVDPSIGMEGYMQFEYI
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEEEC
GDELPHILNMASVVVSRAGSTAISELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCCHH
EVILQDRVSTNTFIHAVNKLYTNKEKYIQNMNGYKKTNDEGIHQIIDIINEVVK
HHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKTILFTGGGTAGHVMINIVLIPKFIEKGWRVEYIGSKNGIEKSLVQNVKYNSVSTGKL
CCEEEEECCCCCCEEEEEEEEEEHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCH
RRYWDWENFKDPFKIIRGCLQSYNLIKKTKPDVIFSAGGFVSVPVAIGAWLNRVPIIIRE
HEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHCCCEEEEC
PDSTLGLANKIALPFATKLCTTFPQTGENVSNEKKVYVGPIVREEIEKGNVLRGRRYCEF
CCCHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHCCCEECCCCCCCC
QQDKPVLLIMGGSQGAKWINDMVRECVDTILLNFNIIHICGKGKVDPSIGMEGYMQFEYI
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEEEC
GDELPHILNMASVVVSRAGSTAISELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCCHH
EVILQDRVSTNTFIHAVNKLYTNKEKYIQNMNGYKKTNDEGIHQIIDIINEVVK
HHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]