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The map label for this gene is comK [H]

Identifier: 218231193

GI number: 218231193

Start: 1156789

End: 1157370

Strand: Direct

Name: comK [H]

Synonym: BCB4264_A1189

Alternate gene names: 218231193

Gene position: 1156789-1157370 (Clockwise)

Preceding gene: 218235750

Following gene: 218231769

Centisome position: 21.35

GC content: 32.99

Gene sequence:

>582_bases
ATGGAAAGTAAAGTGGAACGCTATGTCGAAAATTATGTTGTAACGAAAAATACGATGGCCTTACTTCCTGTTATTCTAAG
TGAAAAGAAAATTGTTACGCGAGTCGTTGAAATGAATGATTCTTTTTTCGTATTTCAAAAACCTCTAGATATTATAGAAA
GAAGTTGCCGCAAGCATGGCTCTAGTTTCTTAGGCAGAAAAGAAGGAACGAAAGAGTTAACTCATATTACACATAAAGCA
CCGATTGCGATTAGTCCAGCAGATCAACTTTATTTTTTCCCTACCTATTCTTACTCTAGAAAAGAGTGTGCTTGGTTGTC
TCATTTTTATATTGAAAGTAATAAAGAATTAAAAGATGGAAATCTTATTATTAGATTTATAAATGGCTTTGCTGTGAAAT
TAGAGATATCAAAAACTAGTTTTGAAAATCAACAAAATCGTACAGCGAAATTACGTACTGAATATGAAGATCGTAGGAAA
AAACAAGGGAATCCTTGTTTTAAAGAGGTTGATAAAAAAGAGGAATCAACATTAAGACCCGCTTATGAGAGTGTGTATTT
TGTGAAGGAAGGCGAAGTGTGA

Upstream 100 bases:

>100_bases
AATTGTAAAAAAGCGGAACTTGTAAGCTATTTCCTTTTCATAGATGCTAAAATTATATATGCAGCTGCTAATATAAATGG
AAAAAAGGAGATAATGGAGT

Downstream 100 bases:

>100_bases
AAGGATGGGGGAATCCCCATTCTTTTTTTGTTTGTCAGTCAGTCTTTGTAGATAAGGCGATATATTAGAAAAAACGAGTT
GTAATTGATATATTTAGAAA

Product: putative competence transcription factor

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MESKVERYVENYVVTKNTMALLPVILSEKKIVTRVVEMNDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPADQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDKKEESTLRPAYESVYFVKEGEV

Sequences:

>Translated_193_residues
MESKVERYVENYVVTKNTMALLPVILSEKKIVTRVVEMNDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPADQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDKKEESTLRPAYESVYFVKEGEV
>Mature_193_residues
MESKVERYVENYVVTKNTMALLPVILSEKKIVTRVVEMNDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPADQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDKKEESTLRPAYESVYFVKEGEV

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22609; Mature: 22609

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKVERYVENYVVTKNTMALLPVILSEKKIVTRVVEMNDSFFVFQKPLDIIERSCRKHG
CCHHHHHHHHHEEECCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHC
SSFLGRKEGTKELTHITHKAPIAISPADQLYFFPTYSYSRKECAWLSHFYIESNKELKDG
HHHHCCCCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHHHHHHEEECCCCCCCCC
NLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRKKQGNPCFKEVDKKEESTLRP
CEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCC
AYESVYFVKEGEV
HHHEEEEEECCCC
>Mature Secondary Structure
MESKVERYVENYVVTKNTMALLPVILSEKKIVTRVVEMNDSFFVFQKPLDIIERSCRKHG
CCHHHHHHHHHEEECCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHC
SSFLGRKEGTKELTHITHKAPIAISPADQLYFFPTYSYSRKECAWLSHFYIESNKELKDG
HHHHCCCCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHHHHHHEEECCCCCCCCC
NLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRKKQGNPCFKEVDKKEESTLRP
CEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCC
AYESVYFVKEGEV
HHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]