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The map label for this gene is kdpD [H]

Identifier: 218230953

GI number: 218230953

Start: 775335

End: 776480

Strand: Direct

Name: kdpD [H]

Synonym: BCB4264_A0800

Alternate gene names: 218230953

Gene position: 775335-776480 (Clockwise)

Preceding gene: 218235311

Following gene: 218234201

Centisome position: 14.31

GC content: 35.86

Gene sequence:

>1146_bases
TTGTATGCAGATGATTATGAACCGAAGTTTCAAAGGCGAACGCCAGAGGAATATTTAGAATATATTCGTCAGCAAAATCG
CGGAAAGTTAAAGCTATATGTAGGAGCAGCTCCAGGCGTAGGAAAAAGTTATAAAATGCTCTTTGATGCAAGGGAAATGA
AAAAAGATGGAATTGATATTGTAATTGGTTTAATTGAAACGCATGGAAGAAAAGAGACGGAAGAAGCAATTGCTGATTTA
GAAAAAGTTCCTTTGAAAGAAATACAGTATAAAGGAAAGGTATTTTATGAGCTTGATGTGGAAGGAATAAAAAAACGCGC
GCCGCAAGTAGTTGTAGTGGATGAACTTGCGCATAGTAATGTTCCTGGTTCTAAACATAAGAAACGTTATATGGATGTGC
AGGAATTGTTAGAGGCTGGTATATCGGTATTATCAGCTTTTAATATTCAACATTTAGAAAGTGTTCATGATATTGTAGCT
CAAATTACGAATGTAAAAGTAAGAGAACGAATTCCAGATTTTATTTTACAAAAAGCAAATGAAATTCAGCTCGTTGATGC
AACGCCCGAGGTATTAAGGAAGAGACTAATAGACGGAAAGATATATAAAGAAGAAAAAATTCAGCAAAGCTTACAAAACT
TCTTTACACTTAATAATTTAGGAGCACTTAGGGAATTATCACTTCGAGAAGTTGCGGATGATATGGACGAGAAAATTAGC
CAAACAGTAATAGAACCGATTGGCGTAAAAGAAAAAATTCTTGTTTGTGTACAATACAGTTCAACAGCGGAGAAATTAAT
ACGACGGGGATGGCGCATGGCTGATCGGTTAAATGCTGAATTGTACGTATTAAACGTTGAGAGGGAAAATATAGATTCTA
TTTCAGCTGGAAAAAAGCAGACGATTGAAGAGTGGAAGGCGCTCACGAATCAATTTGATGCAAGTTTTGTATTAGAAGAA
GCAAAGGGAAGAAAGCCAGCGGATGTTATTATTGAAGTCGCGAAAAGATTGCAAGTAACACAAATTTTACTTGGGCAATC
AGCGAGAACGCGGTGGGAAGAAATTCGAAAAGGTTCTATTGTAAATGAAATTATGAGACAAACAAAGTATATTGATATTC
ATATTGTTGCGGATCAAAGAGGGTAA

Upstream 100 bases:

>100_bases
AGCTAAATTTGGCATTACAGAAATTAATGAAATAGTAACAGTGCTACCTCAATCTAACGGATTGAGGTAGCGTTGTTTCG
AATGAAAGGTAGTGTTTATT

Downstream 100 bases:

>100_bases
AATAGAGCCGACATTTTTGGGGCTCTATTTTAATTTTTGTACAGCATGAAGGCTTAGCATTTTCATTGTATATAAGATTA
CAAGTAAAAACATAATTGCG

Product: sensor histidine kinase KdpD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MYADDYEPKFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLFDAREMKKDGIDIVIGLIETHGRKETEEAIADL
EKVPLKEIQYKGKVFYELDVEGIKKRAPQVVVVDELAHSNVPGSKHKKRYMDVQELLEAGISVLSAFNIQHLESVHDIVA
QITNVKVRERIPDFILQKANEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKIS
QTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVERENIDSISAGKKQTIEEWKALTNQFDASFVLEE
AKGRKPADVIIEVAKRLQVTQILLGQSARTRWEEIRKGSIVNEIMRQTKYIDIHIVADQRG

Sequences:

>Translated_381_residues
MYADDYEPKFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLFDAREMKKDGIDIVIGLIETHGRKETEEAIADL
EKVPLKEIQYKGKVFYELDVEGIKKRAPQVVVVDELAHSNVPGSKHKKRYMDVQELLEAGISVLSAFNIQHLESVHDIVA
QITNVKVRERIPDFILQKANEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKIS
QTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVERENIDSISAGKKQTIEEWKALTNQFDASFVLEE
AKGRKPADVIIEVAKRLQVTQILLGQSARTRWEEIRKGSIVNEIMRQTKYIDIHIVADQRG
>Mature_381_residues
MYADDYEPKFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLFDAREMKKDGIDIVIGLIETHGRKETEEAIADL
EKVPLKEIQYKGKVFYELDVEGIKKRAPQVVVVDELAHSNVPGSKHKKRYMDVQELLEAGISVLSAFNIQHLESVHDIVA
QITNVKVRERIPDFILQKANEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKIS
QTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVERENIDSISAGKKQTIEEWKALTNQFDASFVLEE
AKGRKPADVIIEVAKRLQVTQILLGQSARTRWEEIRKGSIVNEIMRQTKYIDIHIVADQRG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=373, Percent_Identity=36.7292225201072, Blast_Score=261, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02702 KdpD; PF00582 Usp [H]

EC number: 2.7.3.-

Molecular weight: Translated: 43819; Mature: 43819

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYADDYEPKFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLFDAREMKKDGIDI
CCCCCCCCCHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIGLIETHGRKETEEAIADLEKVPLKEIQYKGKVFYELDVEGIKKRAPQVVVVDELAHSN
EEEEHHCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHHHCCCCEEEEEHHHCCC
VPGSKHKKRYMDVQELLEAGISVLSAFNIQHLESVHDIVAQITNVKVRERIPDFILQKAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHCCCC
EIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKIS
CEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVERENIDSISAGKKQ
HHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHH
TIEEWKALTNQFDASFVLEEAKGRKPADVIIEVAKRLQVTQILLGQSARTRWEEIRKGSI
HHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
VNEIMRQTKYIDIHIVADQRG
HHHHHHHCCEEEEEEEECCCC
>Mature Secondary Structure
MYADDYEPKFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLFDAREMKKDGIDI
CCCCCCCCCHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIGLIETHGRKETEEAIADLEKVPLKEIQYKGKVFYELDVEGIKKRAPQVVVVDELAHSN
EEEEHHCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHHHCCCCEEEEEHHHCCC
VPGSKHKKRYMDVQELLEAGISVLSAFNIQHLESVHDIVAQITNVKVRERIPDFILQKAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHCCCC
EIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKIS
CEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVERENIDSISAGKKQ
HHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHH
TIEEWKALTNQFDASFVLEEAKGRKPADVIIEVAKRLQVTQILLGQSARTRWEEIRKGSI
HHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
VNEIMRQTKYIDIHIVADQRG
HHHHHHHCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]