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The map label for this gene is ycsN [H]

Identifier: 218230916

GI number: 218230916

Start: 1932601

End: 1933503

Strand: Reverse

Name: ycsN [H]

Synonym: BCB4264_A2022

Alternate gene names: 218230916

Gene position: 1933503-1932601 (Counterclockwise)

Preceding gene: 218234692

Following gene: 218233765

Centisome position: 35.68

GC content: 37.76

Gene sequence:

>903_bases
ATGGAACGAGTTCAAATGAATGAAACGCTAGAATTCTCTCGTATTATTCAAGGATTTTGGCGTTTAGCAGAATGGAATAT
GACGAAACAAGAATTACTTTCTTTCATTGAAGATTGTATGGATATGGGAATTACTACTTTTGATCACGCTGACATTTACG
GCGGATATACGTGTGAAGGATTGTTTGGAGAAGCTTTACAATTAAAGCCTTCCTTACGAGAAAACATGCAAATTATTACA
AAGTGTGGAATCGCTCCCCCATCACCGAAATTTCCAGAGCGATATGTTGCTCACTACAATACTAGTGCAGAGCACATTAT
TCAAAGTGCAGAAGCATCACTAAAAAATTTACATACAGATTATATTGACGTATTACTTATTCATCGTCCCGATCCTTTTA
TGGATCCAAATGAAGTGGCAAAGGCATTTTCACAATTAAAACAAGAAGGAAAAGTTCGTCACTTCGGTGTATCTAACTTC
TTACCTTCACAATTTAATATGTTAAGTTCGTACTTAGATTTCCCGCTTATTACGAACCAAATTGAAGTTTCTGCATTGCA
GCTTGAGCATTTTGAAAAAGGGACAATTGATTTATGCCAAGAAAAACGAATCAATCCAATGATTTGGTCACCTCTTGCTG
GTGGGGAAATTTTTACTGGTCAATCCGAACGTGCCGTACGTGTACGCGAAACTATGCAAAAAGTTGCTACTGAGCTAGGT
GTTTCTAGTATCGATACGGTTATGTATGCTTGGTTACTTGCTCATCCAGCTAATATGATGCCAATCGTTGGCTCTGGTAA
ATTAGATCGCGTAAAAACGGCCGCTCTTGCTACAAACGTTAACTTAGATCGTCAACAATGGTTTACAATTTTCGAAAGCT
CTAATGGACATCCTGTACCATAA

Upstream 100 bases:

>100_bases
CAAAACATATTTATTGTATGTACACCCCCCAAACTATATAATAATACGTAGTAAGAAAGCCTTTTCAAAATAATAATTAT
TCATCAAGGGGGTACTTATA

Downstream 100 bases:

>100_bases
TACACAAAAAGAAGAGCTGTTTCTTTACAGCTCTTCTTTTTTATATGTATTTCTCGTCATTGCAAATACACACATATCCC
TTAATCCATTTCCATCTACC

Product: oxidoreductase, aldo/keto reductase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MERVQMNETLEFSRIIQGFWRLAEWNMTKQELLSFIEDCMDMGITTFDHADIYGGYTCEGLFGEALQLKPSLRENMQIIT
KCGIAPPSPKFPERYVAHYNTSAEHIIQSAEASLKNLHTDYIDVLLIHRPDPFMDPNEVAKAFSQLKQEGKVRHFGVSNF
LPSQFNMLSSYLDFPLITNQIEVSALQLEHFEKGTIDLCQEKRINPMIWSPLAGGEIFTGQSERAVRVRETMQKVATELG
VSSIDTVMYAWLLAHPANMMPIVGSGKLDRVKTAALATNVNLDRQQWFTIFESSNGHPVP

Sequences:

>Translated_300_residues
MERVQMNETLEFSRIIQGFWRLAEWNMTKQELLSFIEDCMDMGITTFDHADIYGGYTCEGLFGEALQLKPSLRENMQIIT
KCGIAPPSPKFPERYVAHYNTSAEHIIQSAEASLKNLHTDYIDVLLIHRPDPFMDPNEVAKAFSQLKQEGKVRHFGVSNF
LPSQFNMLSSYLDFPLITNQIEVSALQLEHFEKGTIDLCQEKRINPMIWSPLAGGEIFTGQSERAVRVRETMQKVATELG
VSSIDTVMYAWLLAHPANMMPIVGSGKLDRVKTAALATNVNLDRQQWFTIFESSNGHPVP
>Mature_300_residues
MERVQMNETLEFSRIIQGFWRLAEWNMTKQELLSFIEDCMDMGITTFDHADIYGGYTCEGLFGEALQLKPSLRENMQIIT
KCGIAPPSPKFPERYVAHYNTSAEHIIQSAEASLKNLHTDYIDVLLIHRPDPFMDPNEVAKAFSQLKQEGKVRHFGVSNF
LPSQFNMLSSYLDFPLITNQIEVSALQLEHFEKGTIDLCQEKRINPMIWSPLAGGEIFTGQSERAVRVRETMQKVATELG
VSSIDTVMYAWLLAHPANMMPIVGSGKLDRVKTAALATNVNLDRQQWFTIFESSNGHPVP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=196, Percent_Identity=29.0816326530612, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4504825, Length=196, Percent_Identity=29.0816326530612, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI27436966, Length=191, Percent_Identity=26.1780104712042, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI27436964, Length=191, Percent_Identity=26.1780104712042, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI27436962, Length=191, Percent_Identity=26.1780104712042, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI48994888, Length=290, Percent_Identity=52.0689655172414, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=24.6913580246914, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=26.056338028169, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788070, Length=316, Percent_Identity=28.1645569620253, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789375, Length=228, Percent_Identity=25.8771929824561, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082198, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786400, Length=166, Percent_Identity=28.3132530120482, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=313, Percent_Identity=27.4760383386581, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=283, Percent_Identity=24.7349823321555, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=203, Percent_Identity=26.6009852216749, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34032; Mature: 34032

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVQMNETLEFSRIIQGFWRLAEWNMTKQELLSFIEDCMDMGITTFDHADIYGGYTCEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECC
LFGEALQLKPSLRENMQIITKCGIAPPSPKFPERYVAHYNTSAEHIIQSAEASLKNLHTD
HHCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YIDVLLIHRPDPFMDPNEVAKAFSQLKQEGKVRHFGVSNFLPSQFNMLSSYLDFPLITNQ
HEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHHHHCCCCCCCH
IEVSALQLEHFEKGTIDLCQEKRINPMIWSPLAGGEIFTGQSERAVRVRETMQKVATELG
HHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHC
VSSIDTVMYAWLLAHPANMMPIVGSGKLDRVKTAALATNVNLDRQQWFTIFESSNGHPVP
HHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHEEEEECCCCCCCC
>Mature Secondary Structure
MERVQMNETLEFSRIIQGFWRLAEWNMTKQELLSFIEDCMDMGITTFDHADIYGGYTCEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECC
LFGEALQLKPSLRENMQIITKCGIAPPSPKFPERYVAHYNTSAEHIIQSAEASLKNLHTD
HHCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YIDVLLIHRPDPFMDPNEVAKAFSQLKQEGKVRHFGVSNFLPSQFNMLSSYLDFPLITNQ
HEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHHHHCCCCCCCH
IEVSALQLEHFEKGTIDLCQEKRINPMIWSPLAGGEIFTGQSERAVRVRETMQKVATELG
HHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHC
VSSIDTVMYAWLLAHPANMMPIVGSGKLDRVKTAALATNVNLDRQQWFTIFESSNGHPVP
HHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]