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The map label for this gene is dsrK [H]

Identifier: 21675052

GI number: 21675052

Start: 2105551

End: 2107203

Strand: Reverse

Name: dsrK [H]

Synonym: CT2243

Alternate gene names: 21675052

Gene position: 2107203-2105551 (Counterclockwise)

Preceding gene: 21675053

Following gene: 21675051

Centisome position: 97.78

GC content: 57.05

Gene sequence:

>1653_bases
ATGTCCAACAAATACGCCCTCAAACCAGACGAACTCAAAAAAGAGTTCGAACAAAAGAAGCCACGGCTCCTCAAGGGGGA
GTTCGCCGGCAAGGATTGGTGGGATTTGCCGGTGGAGTTCCGTGACGGCAACTGGTGTTTTCCTGCCAAGCCGGAAGTGC
TCGACGAGCTGCACTTCGCCAACCCGAGGAAATGGGCTGCCACCGACAAGGACTGGCAGTTACCCGCAGGATGGGAAAAG
ACGATCCGCGACGGCATGAAGGATCGCCTGAAGCGGTTCCGTTCGTTCAAGGTGTTCATGGACAGCTGCGTGCGCTGCGG
CGCCTGCGCCGACAAGTGCCACTTTTTCCTCGGTACTGGCGATCCGAAGAACATGCCGGTGCTTCGCGCCGAGCTTGTCC
GTTCAGTTTATCGCAACGATTTCACGGGTCTGGCAAAAATCCTGAAGGACTTTTCCGGATCGAGAACGCTCACGCAGGAT
GTGATCAAAGAGTGGCACATGTACTTCCATCAGTGTACCGAGTGCCGCCGCTGTTCGGTTTTCTGTCCGATGGGCATCGA
TACCGCCGAGATTACCATGATGGTGCGCGAGCTGCTCAACCTCATCGGCGTGAACAACAACTGGATTCTCGCGCCGGTGG
CCAACTGCAACCGCACGGGCAATCACCTTGGCATCGAGCCGCACACCTTCAAGCAGAACATCATGTCGATGGTGGATGAC
ATCGAAGATCTCACCGGGGTGCGGGTCAATCCTACCTTCAACCGCAAGGGCGCGGAGATTCTCTTCATTACGCCGTCGGG
CGACGTTTTCGGTGATCCCGGTGTCTATACGATGATGGGCTATCTGCTGCTGTTCCATCACATCGGCCTCGACTACACCA
TCAGCACCTACGCTTCGGAGGGTGGCAACTTCGGCATGTTCACCTCGAACGAAATGATGAAGAAGATCAATGCCAAGATG
TATCACGAGGCCAAGCGTCTCGGGGTGAAGTGGATTCTCGGCGGCGAGTGCGGCCACATGTGGCGCCTGGTGCATCAGTA
CATGAACACCATGAACGGCCCGGCGGATTTCCTCGAGGAGCCGGTTTCGCCAATCACCGGCACGAAGTTCACTAATGCGA
AGGCCACCAAAATGGTGCACATCGTCGAGTTTACCGCTGACCTCATCAAGCACGGCAAGCTCAAGCTCGATCCGAAACGC
AACGACCATCTTCGCACCACCTTCCACGATTCGTGCAATGTGGCTCGCGGCATGGGCATGTTCGAGGAGCCCCGTTACGT
GCTCAACAAGGTGTGCAACGTTTTCCACGAAATGCCCGAGAACACCATCAGGGAGCAGACCTTCTGCTGCGGTTCGGGCA
GCGGCCTGAACGCCGAGGAGTTCATGGACACCCGTATGAGAGGCGGTTTCCCGAGAGCCAGCGCCGTCGCGCACGTGCGC
GAGAAGCACAAGGTCGATTCGCTGGTCACGATCTGCGCCATCGACCGAGCAAGCCTTCCGGCGCTGATGCGCTACTGGAA
TCCGGGCGTGACGGTCTACGGTCTGCACGAGCTGGTTGGTAACGCGCTCATCATGGATGGAGAAAAGAAAAGAACCGAAG
ACCTGAGAGAGAACCCTATGGCCGGATTCGAGGAGGATGACGACGATGAATAA

Upstream 100 bases:

>100_bases
GAATCCCGATATCAAGTTCAGGACTTATGCCGAATACGAAGACGAGTTCCGCGAAAAAATGAAAAAGGCGGGTCTTCCGG
TCGAAAAGCAATAATCAATT

Downstream 100 bases:

>100_bases
GTTCAGTCAGTTTCTGGTCGCCCTCGCCGCAGGTCTGAGCGTCTTTGTGGCGGCATGGTTTTTCATGCAGGTGGCTCACC
GCGGTTCCCTTCCGGCGATC

Product: DsrK protein

Products: NA

Alternate protein names: Hme subunit D [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSNKYALKPDELKKEFEQKKPRLLKGEFAGKDWWDLPVEFRDGNWCFPAKPEVLDELHFANPRKWAATDKDWQLPAGWEK
TIRDGMKDRLKRFRSFKVFMDSCVRCGACADKCHFFLGTGDPKNMPVLRAELVRSVYRNDFTGLAKILKDFSGSRTLTQD
VIKEWHMYFHQCTECRRCSVFCPMGIDTAEITMMVRELLNLIGVNNNWILAPVANCNRTGNHLGIEPHTFKQNIMSMVDD
IEDLTGVRVNPTFNRKGAEILFITPSGDVFGDPGVYTMMGYLLLFHHIGLDYTISTYASEGGNFGMFTSNEMMKKINAKM
YHEAKRLGVKWILGGECGHMWRLVHQYMNTMNGPADFLEEPVSPITGTKFTNAKATKMVHIVEFTADLIKHGKLKLDPKR
NDHLRTTFHDSCNVARGMGMFEEPRYVLNKVCNVFHEMPENTIREQTFCCGSGSGLNAEEFMDTRMRGGFPRASAVAHVR
EKHKVDSLVTICAIDRASLPALMRYWNPGVTVYGLHELVGNALIMDGEKKRTEDLRENPMAGFEEDDDDE

Sequences:

>Translated_550_residues
MSNKYALKPDELKKEFEQKKPRLLKGEFAGKDWWDLPVEFRDGNWCFPAKPEVLDELHFANPRKWAATDKDWQLPAGWEK
TIRDGMKDRLKRFRSFKVFMDSCVRCGACADKCHFFLGTGDPKNMPVLRAELVRSVYRNDFTGLAKILKDFSGSRTLTQD
VIKEWHMYFHQCTECRRCSVFCPMGIDTAEITMMVRELLNLIGVNNNWILAPVANCNRTGNHLGIEPHTFKQNIMSMVDD
IEDLTGVRVNPTFNRKGAEILFITPSGDVFGDPGVYTMMGYLLLFHHIGLDYTISTYASEGGNFGMFTSNEMMKKINAKM
YHEAKRLGVKWILGGECGHMWRLVHQYMNTMNGPADFLEEPVSPITGTKFTNAKATKMVHIVEFTADLIKHGKLKLDPKR
NDHLRTTFHDSCNVARGMGMFEEPRYVLNKVCNVFHEMPENTIREQTFCCGSGSGLNAEEFMDTRMRGGFPRASAVAHVR
EKHKVDSLVTICAIDRASLPALMRYWNPGVTVYGLHELVGNALIMDGEKKRTEDLRENPMAGFEEDDDDE
>Mature_549_residues
SNKYALKPDELKKEFEQKKPRLLKGEFAGKDWWDLPVEFRDGNWCFPAKPEVLDELHFANPRKWAATDKDWQLPAGWEKT
IRDGMKDRLKRFRSFKVFMDSCVRCGACADKCHFFLGTGDPKNMPVLRAELVRSVYRNDFTGLAKILKDFSGSRTLTQDV
IKEWHMYFHQCTECRRCSVFCPMGIDTAEITMMVRELLNLIGVNNNWILAPVANCNRTGNHLGIEPHTFKQNIMSMVDDI
EDLTGVRVNPTFNRKGAEILFITPSGDVFGDPGVYTMMGYLLLFHHIGLDYTISTYASEGGNFGMFTSNEMMKKINAKMY
HEAKRLGVKWILGGECGHMWRLVHQYMNTMNGPADFLEEPVSPITGTKFTNAKATKMVHIVEFTADLIKHGKLKLDPKRN
DHLRTTFHDSCNVARGMGMFEEPRYVLNKVCNVFHEMPENTIREQTFCCGSGSGLNAEEFMDTRMRGGFPRASAVAHVRE
KHKVDSLVTICAIDRASLPALMRYWNPGVTVYGLHELVGNALIMDGEKKRTEDLRENPMAGFEEDDDDE

Specific function: Has menaquinol-oxidizing activity. The hmeC and hmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 62825; Mature: 62694

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKYALKPDELKKEFEQKKPRLLKGEFAGKDWWDLPVEFRDGNWCFPAKPEVLDELHFA
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHCC
NPRKWAATDKDWQLPAGWEKTIRDGMKDRLKRFRSFKVFMDSCVRCGACADKCHFFLGTG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECC
DPKNMPVLRAELVRSVYRNDFTGLAKILKDFSGSRTLTQDVIKEWHMYFHQCTECRRCSV
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
FCPMGIDTAEITMMVRELLNLIGVNNNWILAPVANCNRTGNHLGIEPHTFKQNIMSMVDD
ECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
IEDLTGVRVNPTFNRKGAEILFITPSGDVFGDPGVYTMMGYLLLFHHIGLDYTISTYASE
HHHHCCCEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCC
GGNFGMFTSNEMMKKINAKMYHEAKRLGVKWILGGECGHMWRLVHQYMNTMNGPADFLEE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHC
PVSPITGTKFTNAKATKMVHIVEFTADLIKHGKLKLDPKRNDHLRTTFHDSCNVARGMGM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEHHCCCCHHHCCCC
FEEPRYVLNKVCNVFHEMPENTIREQTFCCGSGSGLNAEEFMDTRMRGGFPRASAVAHVR
CCCCHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
EKHKVDSLVTICAIDRASLPALMRYWNPGVTVYGLHELVGNALIMDGEKKRTEDLRENPM
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHCCEEEECCCHHHHHHHHHCCC
AGFEEDDDDE
CCCCCCCCCC
>Mature Secondary Structure 
SNKYALKPDELKKEFEQKKPRLLKGEFAGKDWWDLPVEFRDGNWCFPAKPEVLDELHFA
CCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHCC
NPRKWAATDKDWQLPAGWEKTIRDGMKDRLKRFRSFKVFMDSCVRCGACADKCHFFLGTG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECC
DPKNMPVLRAELVRSVYRNDFTGLAKILKDFSGSRTLTQDVIKEWHMYFHQCTECRRCSV
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE
FCPMGIDTAEITMMVRELLNLIGVNNNWILAPVANCNRTGNHLGIEPHTFKQNIMSMVDD
ECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
IEDLTGVRVNPTFNRKGAEILFITPSGDVFGDPGVYTMMGYLLLFHHIGLDYTISTYASE
HHHHCCCEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCC
GGNFGMFTSNEMMKKINAKMYHEAKRLGVKWILGGECGHMWRLVHQYMNTMNGPADFLEE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHC
PVSPITGTKFTNAKATKMVHIVEFTADLIKHGKLKLDPKRNDHLRTTFHDSCNVARGMGM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEHHCCCCHHHCCCC
FEEPRYVLNKVCNVFHEMPENTIREQTFCCGSGSGLNAEEFMDTRMRGGFPRASAVAHVR
CCCCHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
EKHKVDSLVTICAIDRASLPALMRYWNPGVTVYGLHELVGNALIMDGEKKRTEDLRENPM
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHCCEEEECCCHHHHHHHHHCCC
AGFEEDDDDE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA