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The map label for this gene is infC

Identifier: 21674936

GI number: 21674936

Start: 2015356

End: 2015997

Strand: Direct

Name: infC

Synonym: CT2127

Alternate gene names: 21674936

Gene position: 2015356-2015997 (Clockwise)

Preceding gene: 21674935

Following gene: 21674937

Centisome position: 93.52

GC content: 52.18

Gene sequence:

>642_bases
ATGAAAAAACAGAAAACATCCGGCAACCAGAAGCCCAAAGTTTCTTACAGGATCAACGAACAGATCCGTGTACCAGAAGT
CAGGGTCGTGTTTCCCGAGGGAGGCATGCAGGTCATGAAAACCCAGGACGCTCGCAGAATGGCCGAAGAGCGAGGGATCG
ACCTTATCGAGGTGCAGCCGAATGCTCAGCCGCCCGTATGCAAGCTTGAGAACTACGGAAAGCTGATCTACAAAATGGAC
AAGAAGGACAAGGACCTCAAGAAAAAACAGAAAACCACGTCGCTCAAAGAGCTGAGGTTCCATCCCAACACCGACAAGCA
CGACTTCGACTTCAAAACCGCGCATCTCGAAGAGTTCCTCCGCAAAGGCAACCGCGTCCGTGCGACCATTGTATTCCTCG
GCCGTTCGATCATTTACAAAGACAAAGGTTTCGAGCTTGCCGACCGCCTGACCGAACGGCTCAGTACGGTCGCCAACCGG
GATGGCGAGCCCAAGTTCGAGGGCAAAAAGCTCTTCGTTTATTTCGAGCCAGACAAGAAAAAAATCGAGCAGTTCGAAAA
GCAGAGGGCTATGGCTGAAAAGATTGCGTCATTGCCGCCGCTACCGCCGGATAATTCCGGAGAGCCGGAAGACGACGAAT
AA

Upstream 100 bases:

>100_bases
AGGGCGACGAAGGCAGCTTCGGCGTTGACGAGCTGATCGCCAGGCTCTGTGAGGAAAGAGATCGACGATTCTGATCTGAC
TATCAACCAAAAAAGATCGA

Downstream 100 bases:

>100_bases
ACGAACAACACTGATAAGCACGACTTTTATCATTTAAACCGACGACCATGCCTAAAATGAAATCACATCGCGGTGCCTGC
AAGAGGTTCAAGGCCACCGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKKQKTSGNQKPKVSYRINEQIRVPEVRVVFPEGGMQVMKTQDARRMAEERGIDLIEVQPNAQPPVCKLENYGKLIYKMD
KKDKDLKKKQKTTSLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELADRLTERLSTVANR
DGEPKFEGKKLFVYFEPDKKKIEQFEKQRAMAEKIASLPPLPPDNSGEPEDDE

Sequences:

>Translated_213_residues
MKKQKTSGNQKPKVSYRINEQIRVPEVRVVFPEGGMQVMKTQDARRMAEERGIDLIEVQPNAQPPVCKLENYGKLIYKMD
KKDKDLKKKQKTTSLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELADRLTERLSTVANR
DGEPKFEGKKLFVYFEPDKKKIEQFEKQRAMAEKIASLPPLPPDNSGEPEDDE
>Mature_213_residues
MKKQKTSGNQKPKVSYRINEQIRVPEVRVVFPEGGMQVMKTQDARRMAEERGIDLIEVQPNAQPPVCKLENYGKLIYKMD
KKDKDLKKKQKTTSLKELRFHPNTDKHDFDFKTAHLEEFLRKGNRVRATIVFLGRSIIYKDKGFELADRLTERLSTVANR
DGEPKFEGKKLFVYFEPDKKKIEQFEKQRAMAEKIASLPPLPPDNSGEPEDDE

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=38.3233532934132, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CHLTE (Q8KAM9)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_663001.1
- ProteinModelPortal:   Q8KAM9
- GeneID:   1007435
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT2127
- NMPDR:   fig|194439.1.peg.2095
- TIGR:   CT2127
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   CTEP194439:CT_2127-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 24811; Mature: 24811

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQKTSGNQKPKVSYRINEQIRVPEVRVVFPEGGMQVMKTQDARRMAEERGIDLIEVQP
CCCCCCCCCCCCEEEEEECCEEECCEEEEEECCCCEEEEHHHHHHHHHHHCCCEEEEECC
NAQPPVCKLENYGKLIYKMDKKDKDLKKKQKTTSLKELRFHPNTDKHDFDFKTAHLEEFL
CCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHH
RKGNRVRATIVFLGRSIIYKDKGFELADRLTERLSTVANRDGEPKFEGKKLFVYFEPDKK
HCCCCEEEEEEEECCHHEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHH
KIEQFEKQRAMAEKIASLPPLPPDNSGEPEDDE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKQKTSGNQKPKVSYRINEQIRVPEVRVVFPEGGMQVMKTQDARRMAEERGIDLIEVQP
CCCCCCCCCCCCEEEEEECCEEECCEEEEEECCCCEEEEHHHHHHHHHHHCCCEEEEECC
NAQPPVCKLENYGKLIYKMDKKDKDLKKKQKTTSLKELRFHPNTDKHDFDFKTAHLEEFL
CCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHH
RKGNRVRATIVFLGRSIIYKDKGFELADRLTERLSTVANRDGEPKFEGKKLFVYFEPDKK
HCCCCEEEEEEEECCHHEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHH
KIEQFEKQRAMAEKIASLPPLPPDNSGEPEDDE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901