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The map label for this gene is rrmA [C]

Identifier: 21674930

GI number: 21674930

Start: 2006555

End: 2007280

Strand: Direct

Name: rrmA [C]

Synonym: CT2121

Alternate gene names: 21674930

Gene position: 2006555-2007280 (Clockwise)

Preceding gene: 21674929

Following gene: 21674932

Centisome position: 93.11

GC content: 56.75

Gene sequence:

>726_bases
GTGCCCATGTCATTCTATTCGAAATTCTCGGAATACTACGAGCGGGTCTTTCCGTTCAGGGAGGATGTCTGGCAATTTCT
GAAAAGATATGCCGGAAGTCCCGGCAATGCGCTGCTCGACGTGGGATGCGGGCCGGGGCACTACTGTGGACGGTTTGCCA
GCGATGGCTTCAACGCACTTGGCATCGACCTCGACGAAGCAATGATCGACGAAGCACAGCGCCGCTATCCCGAAGCTGCA
TTCCGCTGCCTCGACATGCGGCGGCTGGAGAAGACTGAGGGGCGATTCGACTGCGTCTGGTCAATCGGCAACGTCCTGGC
CCACCTCCCCACCGAAGCACTCGCCCCGTTCATCTCGAAAATCCACAATCTGCTCAAACCGGGCGGCTACTGGATCATGC
AGGTGATGAACTGGGACACCCTCGCAGAATTGACGAACTACGACTTCCCGGTGCGCACCATCGAAGCCAACGGTTCAACC
GCCACCTTCCACCGCCACTATTCATCGATCACGCCTGAGTCGTTGCAGTTCACCTTTTCGCTCAAGGATGAAGATTCGGT
GCTATTTGAAGAATCGGTAACGCTCTATCCGGTCGCGATTGAGCGCTACCTGAAGCTGCACGAGGATGCCGGATTTCTGT
ACGAAGGAATGTACTCGGATTTCAGTGGATCGGCGTTAAGGAGTGTGCCCGGCACAGGTTTGGCGCTGGTGTTTGGGCGG
GGGTGA

Upstream 100 bases:

>100_bases
ATCGAAAAAGCGATCCGGTTGATCCGGGGAAAGGATATCAACCGTTAACGGCGTTTTCGGGCAAAAACCGCTGGCTCCCT
GCGCCAGCAACACAACAATC

Downstream 100 bases:

>100_bases
GGAGAGAATCTTCGGAAAAGCTTTTTTTAAAGACAATTACGAGAGAATACTTTCCCATATCTTGCCGGGATCATTGATCG
AAATACTCCGTCCGGCTTTA

Product: methyltransferase, putative

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Menaquinone Biosynthesis Methyltransferase

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MPMSFYSKFSEYYERVFPFREDVWQFLKRYAGSPGNALLDVGCGPGHYCGRFASDGFNALGIDLDEAMIDEAQRRYPEAA
FRCLDMRRLEKTEGRFDCVWSIGNVLAHLPTEALAPFISKIHNLLKPGGYWIMQVMNWDTLAELTNYDFPVRTIEANGST
ATFHRHYSSITPESLQFTFSLKDEDSVLFEESVTLYPVAIERYLKLHEDAGFLYEGMYSDFSGSALRSVPGTGLALVFGR
G

Sequences:

>Translated_241_residues
MPMSFYSKFSEYYERVFPFREDVWQFLKRYAGSPGNALLDVGCGPGHYCGRFASDGFNALGIDLDEAMIDEAQRRYPEAA
FRCLDMRRLEKTEGRFDCVWSIGNVLAHLPTEALAPFISKIHNLLKPGGYWIMQVMNWDTLAELTNYDFPVRTIEANGST
ATFHRHYSSITPESLQFTFSLKDEDSVLFEESVTLYPVAIERYLKLHEDAGFLYEGMYSDFSGSALRSVPGTGLALVFGR
G
>Mature_240_residues
PMSFYSKFSEYYERVFPFREDVWQFLKRYAGSPGNALLDVGCGPGHYCGRFASDGFNALGIDLDEAMIDEAQRRYPEAAF
RCLDMRRLEKTEGRFDCVWSIGNVLAHLPTEALAPFISKIHNLLKPGGYWIMQVMNWDTLAELTNYDFPVRTIEANGSTA
TFHRHYSSITPESLQFTFSLKDEDSVLFEESVTLYPVAIERYLKLHEDAGFLYEGMYSDFSGSALRSVPGTGLALVFGRG

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 27363; Mature: 27232

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSFYSKFSEYYERVFPFREDVWQFLKRYAGSPGNALLDVGCGPGHYCGRFASDGFNAL
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCCCEE
GIDLDEAMIDEAQRRYPEAAFRCLDMRRLEKTEGRFDCVWSIGNVLAHLPTEALAPFISK
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHH
IHNLLKPGGYWIMQVMNWDTLAELTNYDFPVRTIEANGSTATFHRHYSSITPESLQFTFS
HHHHHCCCCCEEEEHHCHHHHHHHHCCCCCEEEEECCCCEEHHHHHHCCCCCCCEEEEEE
LKDEDSVLFEESVTLYPVAIERYLKLHEDAGFLYEGMYSDFSGSALRSVPGTGLALVFGR
ECCCCCEEECCCCEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHCCCCCCEEEEEEC
G
C
>Mature Secondary Structure 
PMSFYSKFSEYYERVFPFREDVWQFLKRYAGSPGNALLDVGCGPGHYCGRFASDGFNAL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHCCCCCEE
GIDLDEAMIDEAQRRYPEAAFRCLDMRRLEKTEGRFDCVWSIGNVLAHLPTEALAPFISK
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHH
IHNLLKPGGYWIMQVMNWDTLAELTNYDFPVRTIEANGSTATFHRHYSSITPESLQFTFS
HHHHHCCCCCEEEEHHCHHHHHHHHCCCCCEEEEECCCCEEHHHHHHCCCCCCCEEEEEE
LKDEDSVLFEESVTLYPVAIERYLKLHEDAGFLYEGMYSDFSGSALRSVPGTGLALVFGR
ECCCCCEEECCCCEEHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHCCCCCCEEEEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA