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The map label for this gene is wecB [H]

Identifier: 21674904

GI number: 21674904

Start: 1986924

End: 1987991

Strand: Reverse

Name: wecB [H]

Synonym: CT2095

Alternate gene names: 21674904

Gene position: 1987991-1986924 (Counterclockwise)

Preceding gene: 21674906

Following gene: 21674902

Centisome position: 92.25

GC content: 60.11

Gene sequence:

>1068_bases
GTGTCCTCTGTGAAAAAAATAGTCTTGATTGCCCAGGATCGTGCGGCGTTTCTCCATGTCGCTCCGCTTGTCAGCGTTTT
CAGAAAAAATGGTGTTTTCGAGTCCGTGCTTGTCCGGGTACTGACTCCTGGCAACCGCGCCGAACACGACGCGCTTGCCG
CTGCATTCGGCTTGTCGGATGAACTCCGCACCATCGAACTGGAGCCATGCACGCCGGTTGCCGAGACCGCTTCGCTTATG
CTTGCGTTAGAGCGGGTGCTCAGTGAACTTGAACCAGCCTTTGTTGTGCCCGGCGGCCACGACAGCGCCAGCCTTGCCGG
TGCGTTTGCCGCCGCGAAAATGGGCATCCCGGTGGTCAGCCTCGACGCAGGCCTGCGCAGTTACGACCGCGCCGAACCCG
AAGAGATCAGCCGCCTCGTCATCGACTCGGTCGCCGCGCTTCACTTCGTCAGCGAGCACAGCGGCATCTACAACCTCATG
AACGAAGGCGTCGCCGATGAGCGCATCCTTTTCGTTGGCAACACGGCCATCGACAGCCTTGTGACGCTGATGGCGCAGGC
TAACCAATCCGGTGTGCTCGAAACGCTCTCGCTTGCCCCGAAAAAGTTCGTCACCGTTCTGCTCAAGCCGGAGCCCTTCG
GAAATCGCGACCTGCTCTGCAAGGTGCTCGAATCGCTTGCCGCCACATCGACCGTGCTGCTTCCGGGCAGTCAGTCGCCC
GAAGATGCGCTCGTTGGCGTTTCGGGGCTCCGGATGATCGATATGCCGGGCTACATCGACCTCCTGCGCCTGCTCAAGGA
GTCGGCGCTCGTACTTACCGACAGCGCCGAGTTCGAGGCTGAACTGACTGTGATGAACGTGCCCTGCATCACCCTGCGTC
AGAGCACCGCCCGCCCCTCGACCGTCGAACTCGGTACCAACGTGCTGATTGATCCCGATGAAGCGGAGATTCTCGAACGT
GCCACGGCCATCCTCTCCGGCAAACAGTTGAAAAAGACGTTGATTCCCGAGAAATGGGACGGCGCGGCATCAAAGCGCAT
AGCCGAAGTGCTCGAACGAGGAGCGTAA

Upstream 100 bases:

>100_bases
ACCATGCGGCTATTGCGATCGATCGTCTTGTTGTCATGCGGCTGGTTCGGGTTTGCTCCGAAGGTTATCGTTCAATTTAT
CAATGTAATAAAGCTTTCCG

Downstream 100 bases:

>100_bases
AGGGCATCAGTTCGGTTTCTCTTGTGTCAAGTCACTGTTGCAACAACCCGGCTCAGTATTCCTTCCTGCCGAACAGCTCC
GGATCGACGCTGGTGCCGTA

Product: UDP-N-acetylglucosamine 2-epimerase, putative

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSSVKKIVLIAQDRAAFLHVAPLVSVFRKNGVFESVLVRVLTPGNRAEHDALAAAFGLSDELRTIELEPCTPVAETASLM
LALERVLSELEPAFVVPGGHDSASLAGAFAAAKMGIPVVSLDAGLRSYDRAEPEEISRLVIDSVAALHFVSEHSGIYNLM
NEGVADERILFVGNTAIDSLVTLMAQANQSGVLETLSLAPKKFVTVLLKPEPFGNRDLLCKVLESLAATSTVLLPGSQSP
EDALVGVSGLRMIDMPGYIDLLRLLKESALVLTDSAEFEAELTVMNVPCITLRQSTARPSTVELGTNVLIDPDEAEILER
ATAILSGKQLKKTLIPEKWDGAASKRIAEVLERGA

Sequences:

>Translated_355_residues
MSSVKKIVLIAQDRAAFLHVAPLVSVFRKNGVFESVLVRVLTPGNRAEHDALAAAFGLSDELRTIELEPCTPVAETASLM
LALERVLSELEPAFVVPGGHDSASLAGAFAAAKMGIPVVSLDAGLRSYDRAEPEEISRLVIDSVAALHFVSEHSGIYNLM
NEGVADERILFVGNTAIDSLVTLMAQANQSGVLETLSLAPKKFVTVLLKPEPFGNRDLLCKVLESLAATSTVLLPGSQSP
EDALVGVSGLRMIDMPGYIDLLRLLKESALVLTDSAEFEAELTVMNVPCITLRQSTARPSTVELGTNVLIDPDEAEILER
ATAILSGKQLKKTLIPEKWDGAASKRIAEVLERGA
>Mature_354_residues
SSVKKIVLIAQDRAAFLHVAPLVSVFRKNGVFESVLVRVLTPGNRAEHDALAAAFGLSDELRTIELEPCTPVAETASLML
ALERVLSELEPAFVVPGGHDSASLAGAFAAAKMGIPVVSLDAGLRSYDRAEPEEISRLVIDSVAALHFVSEHSGIYNLMN
EGVADERILFVGNTAIDSLVTLMAQANQSGVLETLSLAPKKFVTVLLKPEPFGNRDLLCKVLESLAATSTVLLPGSQSPE
DALVGVSGLRMIDMPGYIDLLRLLKESALVLTDSAEFEAELTVMNVPCITLRQSTARPSTVELGTNVLIDPDEAEILERA
TAILSGKQLKKTLIPEKWDGAASKRIAEVLERGA

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=28.2258064516129, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 37931; Mature: 37800

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVKKIVLIAQDRAAFLHVAPLVSVFRKNGVFESVLVRVLTPGNRAEHDALAAAFGLSD
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
ELRTIELEPCTPVAETASLMLALERVLSELEPAFVVPGGHDSASLAGAFAAAKMGIPVVS
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCEEE
LDAGLRSYDRAEPEEISRLVIDSVAALHFVSEHSGIYNLMNEGVADERILFVGNTAIDSL
ECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEECHHHHHH
VTLMAQANQSGVLETLSLAPKKFVTVLLKPEPFGNRDLLCKVLESLAATSTVLLPGSQSP
HHHHHHCCCCCHHHHHHHCCCHHEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCC
EDALVGVSGLRMIDMPGYIDLLRLLKESALVLTDSAEFEAELTVMNVPCITLRQSTARPS
HHHHCCCCCCEEECCCCHHHHHHHHHHCCEEEECCCCCEEEEEEEECCEEEEECCCCCCC
TVELGTNVLIDPDEAEILERATAILSGKQLKKTLIPEKWDGAASKRIAEVLERGA
EEECCCCEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSVKKIVLIAQDRAAFLHVAPLVSVFRKNGVFESVLVRVLTPGNRAEHDALAAAFGLSD
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
ELRTIELEPCTPVAETASLMLALERVLSELEPAFVVPGGHDSASLAGAFAAAKMGIPVVS
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCEEE
LDAGLRSYDRAEPEEISRLVIDSVAALHFVSEHSGIYNLMNEGVADERILFVGNTAIDSL
ECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEECHHHHHH
VTLMAQANQSGVLETLSLAPKKFVTVLLKPEPFGNRDLLCKVLESLAATSTVLLPGSQSP
HHHHHHCCCCCHHHHHHHCCCHHEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCC
EDALVGVSGLRMIDMPGYIDLLRLLKESALVLTDSAEFEAELTVMNVPCITLRQSTARPS
HHHHCCCCCCEEECCCCHHHHHHHHHHCCEEEECCCCCEEEEEEEECCEEEEECCCCCCC
TVELGTNVLIDPDEAEILERATAILSGKQLKKTLIPEKWDGAASKRIAEVLERGA
EEECCCCEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA