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The map label for this gene is kup

Identifier: 21674883

GI number: 21674883

Start: 1965375

End: 1967216

Strand: Reverse

Name: kup

Synonym: CT2073

Alternate gene names: 21674883

Gene position: 1967216-1965375 (Counterclockwise)

Preceding gene: 21674885

Following gene: 21674882

Centisome position: 91.29

GC content: 54.02

Gene sequence:

>1842_bases
TTGTCGCTTGCCGCGCTTGGCGTGGTGTTTGGGGATATTGGTACCAGTCCTCTCTATGCCATCCGCGAATGTTTTCATGG
CGAATTCAGCATTCCCGTGAACACTCCCAACGTGCTCGGAGTACTTTCTCTGCTGATCTGGGCACTACTCCTGATTGTTA
CCCTGAAGTACCTGACCTTTATTATGAAGGCTGATAACGAAGGGGAGGGGGGGATTCTGGCACTGACCGCTCTGATCATT
TCCCACAGCAAGAAGAACAAAAGCGAACGGTGGATTCTGGTCAGTCTCGGCCTGTTTGGTGCGGCGCTGCTCTATGGCGA
CGGTATGATTACGCCGTCGATCTCGGTGCTCAGCGCTGTCGAGGGTATCCAGATCATCGCCCCCAGCTTCGGTCCGCTGG
TTATTCCCGTGACCATCGCCATCCTTGCCGGGCTGTTCCTTTTTCAGCATCATGGCACGGCCAAGGTTGGTTCATTTTTC
GGCCCGATTATTTTGCTCTGGTTCACCTCGATCGGGCTGTGCGGTCTGGTAGAGATTGTCAAGTATCCGGCGATTCTGAA
GGCGGTATTTCCCTGGTATGGGCTGGAGTTTCTCGTAAACAATCACGCTAAAGGCTTTCTGGTGCTTGGCGCTGTCTTTC
TTGCCGTTACCGGCGCCGAGGCGCTGTATGCCGATATGGGCCATTTTGGACGGCGGCCGATCCGGCTGACCTGGAGCCTG
CTGGTGTTGCCGGCTTTGTTGTTGAATTATTTCGGCCAGGGGGCGGTGCTGCTCTCCGAACCAGCCAAGTCCTGGAATCC
ATTCTATGCCCTGGTTCCGTCATGGGGCATCATTCCGATGGTCATTCTGGCCACGCTTGCCACCATCATCGCTTCTCAGG
CGCTTATCACGGGGATCTTTTCGCTGACCCAGCAGGGTATCCAGCTCGGTTATATTCCGAGGCTCACCGTACAGCATACC
TCAGCCAGTCATATTGGCCAGATTTACGTTCCAGCGGCCAACTGGGCGCTGATGTTCTCGACGATTGCCCTTGTCGCCGG
GTTCGGCTCCTCGAGTAAACTTGCCTCGGCTTACGGTGTGGCCGTGACGGCGACCATGCTGATTTCTGCCGTGCTATTTT
ACTATGTCGCTCGTGATCTCTGGAACTGGAACCGTCTTGGCCTCAATCTGTTGATGGGCATGTTCATGCTGATCGATCTG
TCGTTTTTCGGGGCCAGCGTCAGCAAGCTTTTCCACGGCGCCTGGTTCCCGCTGGTTATCGGGTTTGCGCTGTTCACCCT
CATGCTGACCTGGAAGCAGGGGCGTTTGCTTCTGATGAAGCAGATTCAGGATCGTACGCTCACGGTCAGCGAGTTCACCG
AAAGCCTCGCCATTCAGCAGCCGCAGCGGGTCAAGGGGCAGGCAATCTATCTGACGGCCAACCCTGATGTGGTGCCGATG
GCTCTGTTACACAATATGCGCCACAACAAGATTCTGCATTCAGAGGTAGGCCTGTTGCATTTCTCCACCGAGCGTGTGCC
TCGTGTGCCGAACAGCAAAAAAGTGGAAGTCATTCAGCTCAATTACGGGATGTACAAGATTATCGCCCGGTATGGCTTCA
TGGAGTATCCCAACATCAGGCAGGTGCTTGCTCTTGCTAACCAGCAGGGAATGCATTTCAGGACTGATGCAATCAGCTAT
TTTATCAATCGGGAAAAGATCGTTACGGGTATGAAATCGAAAATGAGCGTCTGGCGAAAAAAATTGTTCGCGCTTATGGC
CCGCAATGCACTGAGCGCTACGGCTTACTACGATCTTCCCTCGGGGCAGGTTATCGAAATAGGTGTGCAGGTACAGATTT
AA

Upstream 100 bases:

>100_bases
TTTGTGGTAACAAGACTTTTCCTGCCCTATGTCAACGACGTCAGACGAATCCCATTTATCTTTCTCCTCCGATAATTTTG
ATTTCAAGCGTCTTGTTACC

Downstream 100 bases:

>100_bases
TACTGCTTTTCCCGCGCTTGTATTTGTCTTCTGTATACTATTCTCTATATTGATATAGAGAAAGGGAAAAGAGCTTTCTG
TATTTTGATGCAAGAACTTG

Product: Kup system potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MSLAALGVVFGDIGTSPLYAIRECFHGEFSIPVNTPNVLGVLSLLIWALLLIVTLKYLTFIMKADNEGEGGILALTALII
SHSKKNKSERWILVSLGLFGAALLYGDGMITPSISVLSAVEGIQIIAPSFGPLVIPVTIAILAGLFLFQHHGTAKVGSFF
GPIILLWFTSIGLCGLVEIVKYPAILKAVFPWYGLEFLVNNHAKGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWSL
LVLPALLLNYFGQGAVLLSEPAKSWNPFYALVPSWGIIPMVILATLATIIASQALITGIFSLTQQGIQLGYIPRLTVQHT
SASHIGQIYVPAANWALMFSTIALVAGFGSSSKLASAYGVAVTATMLISAVLFYYVARDLWNWNRLGLNLLMGMFMLIDL
SFFGASVSKLFHGAWFPLVIGFALFTLMLTWKQGRLLLMKQIQDRTLTVSEFTESLAIQQPQRVKGQAIYLTANPDVVPM
ALLHNMRHNKILHSEVGLLHFSTERVPRVPNSKKVEVIQLNYGMYKIIARYGFMEYPNIRQVLALANQQGMHFRTDAISY
FINREKIVTGMKSKMSVWRKKLFALMARNALSATAYYDLPSGQVIEIGVQVQI

Sequences:

>Translated_613_residues
MSLAALGVVFGDIGTSPLYAIRECFHGEFSIPVNTPNVLGVLSLLIWALLLIVTLKYLTFIMKADNEGEGGILALTALII
SHSKKNKSERWILVSLGLFGAALLYGDGMITPSISVLSAVEGIQIIAPSFGPLVIPVTIAILAGLFLFQHHGTAKVGSFF
GPIILLWFTSIGLCGLVEIVKYPAILKAVFPWYGLEFLVNNHAKGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWSL
LVLPALLLNYFGQGAVLLSEPAKSWNPFYALVPSWGIIPMVILATLATIIASQALITGIFSLTQQGIQLGYIPRLTVQHT
SASHIGQIYVPAANWALMFSTIALVAGFGSSSKLASAYGVAVTATMLISAVLFYYVARDLWNWNRLGLNLLMGMFMLIDL
SFFGASVSKLFHGAWFPLVIGFALFTLMLTWKQGRLLLMKQIQDRTLTVSEFTESLAIQQPQRVKGQAIYLTANPDVVPM
ALLHNMRHNKILHSEVGLLHFSTERVPRVPNSKKVEVIQLNYGMYKIIARYGFMEYPNIRQVLALANQQGMHFRTDAISY
FINREKIVTGMKSKMSVWRKKLFALMARNALSATAYYDLPSGQVIEIGVQVQI
>Mature_612_residues
SLAALGVVFGDIGTSPLYAIRECFHGEFSIPVNTPNVLGVLSLLIWALLLIVTLKYLTFIMKADNEGEGGILALTALIIS
HSKKNKSERWILVSLGLFGAALLYGDGMITPSISVLSAVEGIQIIAPSFGPLVIPVTIAILAGLFLFQHHGTAKVGSFFG
PIILLWFTSIGLCGLVEIVKYPAILKAVFPWYGLEFLVNNHAKGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWSLL
VLPALLLNYFGQGAVLLSEPAKSWNPFYALVPSWGIIPMVILATLATIIASQALITGIFSLTQQGIQLGYIPRLTVQHTS
ASHIGQIYVPAANWALMFSTIALVAGFGSSSKLASAYGVAVTATMLISAVLFYYVARDLWNWNRLGLNLLMGMFMLIDLS
FFGASVSKLFHGAWFPLVIGFALFTLMLTWKQGRLLLMKQIQDRTLTVSEFTESLAIQQPQRVKGQAIYLTANPDVVPMA
LLHNMRHNKILHSEVGLLHFSTERVPRVPNSKKVEVIQLNYGMYKIIARYGFMEYPNIRQVLALANQQGMHFRTDAISYF
INREKIVTGMKSKMSVWRKKLFALMARNALSATAYYDLPSGQVIEIGVQVQI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=615, Percent_Identity=44.2276422764228, Blast_Score=560, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_CHLTE (Q8KAT2)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662948.1
- GeneID:   1007486
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT2073
- NMPDR:   fig|194439.1.peg.2042
- TIGR:   CT2073
- HOGENOM:   HBG351154
- OMA:   KECFSPE
- ProtClustDB:   CLSK638076
- BioCyc:   CTEP194439:CT_2073-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 67391; Mature: 67260

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe9e05ac)-; HASH(0xfd254cc)-; HASH(0x8b19c28)-; HASH(0xfd25358)-; HASH(0xfd4d134)-; HASH(0xfd504e0)-; HASH(0xfcf148c)-; HASH(0xfd222ec)-; HASH(0xfc65cb4)-; HASH(0xf0bbc28)-; HASH(0xfd3e2ec)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAALGVVFGDIGTSPLYAIRECFHGEFSIPVNTPNVLGVLSLLIWALLLIVTLKYLTF
CCHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IMKADNEGEGGILALTALIISHSKKNKSERWILVSLGLFGAALLYGDGMITPSISVLSAV
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHH
EGIQIIAPSFGPLVIPVTIAILAGLFLFQHHGTAKVGSFFGPIILLWFTSIGLCGLVEIV
CCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KYPAILKAVFPWYGLEFLVNNHAKGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWSL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHH
LVLPALLLNYFGQGAVLLSEPAKSWNPFYALVPSWGIIPMVILATLATIIASQALITGIF
HHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLTQQGIQLGYIPRLTVQHTSASHIGQIYVPAANWALMFSTIALVAGFGSSSKLASAYGV
HHHHCCCEECCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVTATMLISAVLFYYVARDLWNWNRLGLNLLMGMFMLIDLSFFGASVSKLFHGAWFPLVI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GFALFTLMLTWKQGRLLLMKQIQDRTLTVSEFTESLAIQQPQRVKGQAIYLTANPDVVPM
HHHHHHHHHHHCCCCCHHHHHHCCCEEEHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
ALLHNMRHNKILHSEVGLLHFSTERVPRVPNSKKVEVIQLNYGMYKIIARYGFMEYPNIR
HHHHHHHHCCCHHHCCCEEEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCHH
QVLALANQQGMHFRTDAISYFINREKIVTGMKSKMSVWRKKLFALMARNALSATAYYDLP
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
SGQVIEIGVQVQI
CCCEEEEEEEEEH
>Mature Secondary Structure 
SLAALGVVFGDIGTSPLYAIRECFHGEFSIPVNTPNVLGVLSLLIWALLLIVTLKYLTF
CHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IMKADNEGEGGILALTALIISHSKKNKSERWILVSLGLFGAALLYGDGMITPSISVLSAV
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHH
EGIQIIAPSFGPLVIPVTIAILAGLFLFQHHGTAKVGSFFGPIILLWFTSIGLCGLVEIV
CCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KYPAILKAVFPWYGLEFLVNNHAKGFLVLGAVFLAVTGAEALYADMGHFGRRPIRLTWSL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHH
LVLPALLLNYFGQGAVLLSEPAKSWNPFYALVPSWGIIPMVILATLATIIASQALITGIF
HHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLTQQGIQLGYIPRLTVQHTSASHIGQIYVPAANWALMFSTIALVAGFGSSSKLASAYGV
HHHHCCCEECCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVTATMLISAVLFYYVARDLWNWNRLGLNLLMGMFMLIDLSFFGASVSKLFHGAWFPLVI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GFALFTLMLTWKQGRLLLMKQIQDRTLTVSEFTESLAIQQPQRVKGQAIYLTANPDVVPM
HHHHHHHHHHHCCCCCHHHHHHCCCEEEHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
ALLHNMRHNKILHSEVGLLHFSTERVPRVPNSKKVEVIQLNYGMYKIIARYGFMEYPNIR
HHHHHHHHCCCHHHCCCEEEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCHH
QVLALANQQGMHFRTDAISYFINREKIVTGMKSKMSVWRKKLFALMARNALSATAYYDLP
HHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
SGQVIEIGVQVQI
CCCEEEEEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901