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The map label for this gene is 21674880

Identifier: 21674880

GI number: 21674880

Start: 1962351

End: 1963535

Strand: Reverse

Name: 21674880

Synonym: CT2070

Alternate gene names: NA

Gene position: 1963535-1962351 (Counterclockwise)

Preceding gene: 21674881

Following gene: 21674879

Centisome position: 91.12

GC content: 54.68

Gene sequence:

>1185_bases
ATGCGTTTGATTCTCATGACAGGTAAAGGTGGCGTTGGCAAAACCTCTACGGCTGCGGCTACCGGTCTGCGTTGTGCTGA
GCTGGGTTACAGAACCTTGGTTCTGAGCACTGACCCGGCGCATTCGCTTGCCGACAGTTTCGATGTGCCGCTTGGCCATG
AGCCTCGCAAGATTTGCGAGAACCTCTGGGGCGCGGAACTTGATGTGCTCGAAGAGCTCGAGCACAACTGGGGCAGCGTC
AAACGCTATATGACCGAAGTGCTTCAGGCCAGGGGGCTGGATGGCGTGCAGGCCGAAGAACTTTCCATCCTGCCCGGCAT
GGATGAAATTTTCGGGCTGGTCAGGGTGTTTCGCCATCACAAGGAGGGCAATTTCGATGTGCTGATCATCGATTCTGCTC
CTACCGGCACAGCATTGCGCCTCCTGAGCATTCCCGAAGTGGGTGGCTGGTACATGCGACGGTTGTACAAGCCGCTCGAA
AAGATGGCTGTGTACCTGAGGCCGCTGGTGGAGCCGATTTTCAAGCCGCTTGCCGGCTTTTCGCTGCCCGACAAGGAGAT
GATGGATCTTCCTTACGAATTTTACGAGCAGATCGAAGCGCTGGGCAAGATACTGACCGACAACAATGTGACGTCCGTGC
GCCTGGTTACGAATCCCGAAAAGATGGTCATCAAGGAGTCCCTGCGGGCGCAGGCTTATCTCAGCCTCTATAACATCGCC
ATCGACATGGTTGTTGCCAACCGGATCATTCCCGATGAGGTGACCGATCCCTATTTCCAGTACTGGAAGGAGAACCAGAA
GCTTTACAGGCAGGAGATTATCGACAGTTTCAGTCCGCTGCCTGTCAGGGAGGTGCCTCTCTATTCAAGGGAAATATGCG
GTATGGCCACCCTTGAAAAACTCAAAGAGATGCTTTACGGAGACGAGGATCCTTCACAGGTTTATTTCCGGCGGAATCCC
TATCAGATCAAACAGTCGGAAGGCGGATACGATCTTGAACTGCTGCTTCCGGGCCTTCCTGATGACTCAGTTCAGTTGAG
CAAGAGTGGTGACGAGCTGAATATCAGGATCGGTAACCACCGGCGGAACATGGTACTGCCTCAGGCGCTGGCGACGCTTA
GAACCACCGGGGCGCGATGGGAGGGTGACCGGCTTATCATCGGCTTTTCAGAAGAGCTTTCGTGA

Upstream 100 bases:

>100_bases
CATGGGGTGGTATTGCTCTGTCCCCGGATCGAGGGCATGGCAGGGAAGAACAAACTATTTTTTCTCGGCTGTGGTTGGTT
AAGAAAAAAAAGGAGCGTGT

Downstream 100 bases:

>100_bases
GTGGGCTGCCGGAGAGATGCAGATAGGCAACACAGCTCCTGCTTCTAAAGGATGAAAAAAAGTGTAGCGTTTTTTTGATT
TTTTTTATACAATCAACGGT

Product: ArsA ATPase family protein

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRLILMTGKGGVGKTSTAAATGLRCAELGYRTLVLSTDPAHSLADSFDVPLGHEPRKICENLWGAELDVLEELEHNWGSV
KRYMTEVLQARGLDGVQAEELSILPGMDEIFGLVRVFRHHKEGNFDVLIIDSAPTGTALRLLSIPEVGGWYMRRLYKPLE
KMAVYLRPLVEPIFKPLAGFSLPDKEMMDLPYEFYEQIEALGKILTDNNVTSVRLVTNPEKMVIKESLRAQAYLSLYNIA
IDMVVANRIIPDEVTDPYFQYWKENQKLYRQEIIDSFSPLPVREVPLYSREICGMATLEKLKEMLYGDEDPSQVYFRRNP
YQIKQSEGGYDLELLLPGLPDDSVQLSKSGDELNIRIGNHRRNMVLPQALATLRTTGARWEGDRLIIGFSEELS

Sequences:

>Translated_394_residues
MRLILMTGKGGVGKTSTAAATGLRCAELGYRTLVLSTDPAHSLADSFDVPLGHEPRKICENLWGAELDVLEELEHNWGSV
KRYMTEVLQARGLDGVQAEELSILPGMDEIFGLVRVFRHHKEGNFDVLIIDSAPTGTALRLLSIPEVGGWYMRRLYKPLE
KMAVYLRPLVEPIFKPLAGFSLPDKEMMDLPYEFYEQIEALGKILTDNNVTSVRLVTNPEKMVIKESLRAQAYLSLYNIA
IDMVVANRIIPDEVTDPYFQYWKENQKLYRQEIIDSFSPLPVREVPLYSREICGMATLEKLKEMLYGDEDPSQVYFRRNP
YQIKQSEGGYDLELLLPGLPDDSVQLSKSGDELNIRIGNHRRNMVLPQALATLRTTGARWEGDRLIIGFSEELS
>Mature_394_residues
MRLILMTGKGGVGKTSTAAATGLRCAELGYRTLVLSTDPAHSLADSFDVPLGHEPRKICENLWGAELDVLEELEHNWGSV
KRYMTEVLQARGLDGVQAEELSILPGMDEIFGLVRVFRHHKEGNFDVLIIDSAPTGTALRLLSIPEVGGWYMRRLYKPLE
KMAVYLRPLVEPIFKPLAGFSLPDKEMMDLPYEFYEQIEALGKILTDNNVTSVRLVTNPEKMVIKESLRAQAYLSLYNIA
IDMVVANRIIPDEVTDPYFQYWKENQKLYRQEIIDSFSPLPVREVPLYSREICGMATLEKLKEMLYGDEDPSQVYFRRNP
YQIKQSEGGYDLELLLPGLPDDSVQLSKSGDELNIRIGNHRRNMVLPQALATLRTTGARWEGDRLIIGFSEELS

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=287, Percent_Identity=24.390243902439, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557003, Length=280, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320103, Length=318, Percent_Identity=27.0440251572327, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24586297, Length=306, Percent_Identity=23.202614379085, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44672; Mature: 44672

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILMTGKGGVGKTSTAAATGLRCAELGYRTLVLSTDPAHSLADSFDVPLGHEPRKICE
CEEEEEECCCCCCCCCHHHHHCCHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCHHHHHH
NLWGAELDVLEELEHNWGSVKRYMTEVLQARGLDGVQAEELSILPGMDEIFGLVRVFRHH
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHC
KEGNFDVLIIDSAPTGTALRLLSIPEVGGWYMRRLYKPLEKMAVYLRPLVEPIFKPLAGF
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDKEMMDLPYEFYEQIEALGKILTDNNVTSVRLVTNPEKMVIKESLRAQAYLSLYNIA
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
IDMVVANRIIPDEVTDPYFQYWKENQKLYRQEIIDSFSPLPVREVPLYSREICGMATLEK
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LKEMLYGDEDPSQVYFRRNPYQIKQSEGGYDLELLLPGLPDDSVQLSKSGDELNIRIGNH
HHHHHCCCCCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCCEEEECCCCEEEEEECCC
RRNMVLPQALATLRTTGARWEGDRLIIGFSEELS
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRLILMTGKGGVGKTSTAAATGLRCAELGYRTLVLSTDPAHSLADSFDVPLGHEPRKICE
CEEEEEECCCCCCCCCHHHHHCCHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCHHHHHH
NLWGAELDVLEELEHNWGSVKRYMTEVLQARGLDGVQAEELSILPGMDEIFGLVRVFRHH
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHC
KEGNFDVLIIDSAPTGTALRLLSIPEVGGWYMRRLYKPLEKMAVYLRPLVEPIFKPLAGF
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDKEMMDLPYEFYEQIEALGKILTDNNVTSVRLVTNPEKMVIKESLRAQAYLSLYNIA
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
IDMVVANRIIPDEVTDPYFQYWKENQKLYRQEIIDSFSPLPVREVPLYSREICGMATLEK
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LKEMLYGDEDPSQVYFRRNPYQIKQSEGGYDLELLLPGLPDDSVQLSKSGDELNIRIGNH
HHHHHCCCCCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCCEEEECCCCEEEEEECCC
RRNMVLPQALATLRTTGARWEGDRLIIGFSEELS
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]