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The map label for this gene is sglT [H]

Identifier: 21674868

GI number: 21674868

Start: 1953950

End: 1955359

Strand: Direct

Name: sglT [H]

Synonym: CT2058

Alternate gene names: 21674868

Gene position: 1953950-1955359 (Clockwise)

Preceding gene: 21674867

Following gene: 21674869

Centisome position: 90.67

GC content: 59.93

Gene sequence:

>1410_bases
ATGCAACCTCTCGATTACGCCATCATCATTCTCTTTCTGGCGGGCAACATGATGCTCGGTCTGTGGCAAGGACGGAGCAA
CAAGCAGACCTCCGACTACTTTCTCGGCGGCCACAAGCTTCCGTGGTTCGCGGTGATGCTCTCCATCGTGGCCACCGAAA
CCTCGGTGCTGACCTTCGTGAGCGTTCCGGGCCTGGCCTACCGGGGCGACTGGAGCTTCCTCCAGCTCGCGTTCGGCTAC
ATCGTCGGGCGGATTCTGGTCAGCTTCATCCTGCTGCCCACCTATTTCAAACATGGCGTCACCTCGATCTATGAGGTGAT
CGGCATGAGGTTCGGCCACGGTATCCAGAAAACCGCCTCGGTGATTTTTCTGATAACGAGGATTCTGGGCGACGGTATCC
GCTTCCTCGCGACCGGCGTGGTGGTGCAGGCGGTCACCGGCTGGCCGCTCTCGCTCTCGGTGCTGGTCATCGGCATTGTC
ACCCTCGTCTACACCATTTCGGGCGGGCTGAAAACCGTGGTGTGGCTCGACAGCATCCAGTTCGGGCTGTACCTCGGTGG
CGGCGTTATCGCCATCGCCTTCATCCTCGCCCGCCTCGACGCGCCGCTGCCCGATCTTCTCGCGCCGCTCCTGGCCGCCG
GAAAGCTGAAAATCATCGACACCGACCCGCACATCTTCACCAACCCGCTCTCGTTTGTCAGCGCCTTTTCCGGCGGTATC
CTTCTTTCGCTCTGCTCGCACGGCGTCGATTACCTGATGGTGCAGCGCGTGCTCGGCTGCGACGGCCTCGGCTCGGCCCG
CAAGGCGATGATCGCCAGCGGCGTGTTCGTACTCTTCCAGTTTGCGCTGTTCCTCCTGGCAGGTTCGCTGATCTATGTGT
TTTTCCATGGTGCGCCACTCGTCAAAGATCGCGAATTCACCAGTTTCATCGTCAGAGCACTGCCCGCCGGCCTCAAGGGG
CTGCTGCTGGCCGGAATTCTTTCTGCCGCCATGTCAACCTTGGCCTCATCGATCAACTCACTGGCCGCTTCGACGGTCAC
CGACCTCATAAAAGGCAAGGCGTCGCTCAGCACATCACGCCTCATCAGCGTCGCCTGGGCCGCTGTGCTGATCGGCATCG
CCCTTGTGTTCAACGAAAACGACAAGGCAATCGTCATGCTTGGCCTCGAAATCGCCTCGTTCACCTATGGCGGCCTGCTC
GGGCTGTTCCTGCTCTCGAAAAGCAGCCGCAATTTCCACTCAACGAGCCTCATCGCCGGACTGCTGGCCAGTATGGCGGT
GGTGTTCCTGCTCAAGCTCCTCGGCCTGGCATGGACATGGTACATTGCCGTTTCTGTAACGACTAACATCCTGACGACAG
CCGGAGTCGAAGCGTTGCTTCCCGACAGGGAGTCTTTTGCACGGGAATAA

Upstream 100 bases:

>100_bases
CGCTTCGTGGGAAAAAGACGAGGCAGAGTTCGCGGCGATCAAACCCAACTTCCACCTGTACAACAACTGACATCACAACC
GATCCGGGCACCTGTTGAGC

Downstream 100 bases:

>100_bases
CCGTGTTTGCGAACAAACCTTTATCTTGTGTAAATAGTATATGAGATAATGGCCCCATCTACCGCCCGTGTCGCAATGTA
CCAGAGTAGGGTTTCTGAAT

Product: sodium:solute symporter family protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MQPLDYAIIILFLAGNMMLGLWQGRSNKQTSDYFLGGHKLPWFAVMLSIVATETSVLTFVSVPGLAYRGDWSFLQLAFGY
IVGRILVSFILLPTYFKHGVTSIYEVIGMRFGHGIQKTASVIFLITRILGDGIRFLATGVVVQAVTGWPLSLSVLVIGIV
TLVYTISGGLKTVVWLDSIQFGLYLGGGVIAIAFILARLDAPLPDLLAPLLAAGKLKIIDTDPHIFTNPLSFVSAFSGGI
LLSLCSHGVDYLMVQRVLGCDGLGSARKAMIASGVFVLFQFALFLLAGSLIYVFFHGAPLVKDREFTSFIVRALPAGLKG
LLLAGILSAAMSTLASSINSLAASTVTDLIKGKASLSTSRLISVAWAAVLIGIALVFNENDKAIVMLGLEIASFTYGGLL
GLFLLSKSSRNFHSTSLIAGLLASMAVVFLLKLLGLAWTWYIAVSVTTNILTTAGVEALLPDRESFARE

Sequences:

>Translated_469_residues
MQPLDYAIIILFLAGNMMLGLWQGRSNKQTSDYFLGGHKLPWFAVMLSIVATETSVLTFVSVPGLAYRGDWSFLQLAFGY
IVGRILVSFILLPTYFKHGVTSIYEVIGMRFGHGIQKTASVIFLITRILGDGIRFLATGVVVQAVTGWPLSLSVLVIGIV
TLVYTISGGLKTVVWLDSIQFGLYLGGGVIAIAFILARLDAPLPDLLAPLLAAGKLKIIDTDPHIFTNPLSFVSAFSGGI
LLSLCSHGVDYLMVQRVLGCDGLGSARKAMIASGVFVLFQFALFLLAGSLIYVFFHGAPLVKDREFTSFIVRALPAGLKG
LLLAGILSAAMSTLASSINSLAASTVTDLIKGKASLSTSRLISVAWAAVLIGIALVFNENDKAIVMLGLEIASFTYGGLL
GLFLLSKSSRNFHSTSLIAGLLASMAVVFLLKLLGLAWTWYIAVSVTTNILTTAGVEALLPDRESFARE
>Mature_469_residues
MQPLDYAIIILFLAGNMMLGLWQGRSNKQTSDYFLGGHKLPWFAVMLSIVATETSVLTFVSVPGLAYRGDWSFLQLAFGY
IVGRILVSFILLPTYFKHGVTSIYEVIGMRFGHGIQKTASVIFLITRILGDGIRFLATGVVVQAVTGWPLSLSVLVIGIV
TLVYTISGGLKTVVWLDSIQFGLYLGGGVIAIAFILARLDAPLPDLLAPLLAAGKLKIIDTDPHIFTNPLSFVSAFSGGI
LLSLCSHGVDYLMVQRVLGCDGLGSARKAMIASGVFVLFQFALFLLAGSLIYVFFHGAPLVKDREFTSFIVRALPAGLKG
LLLAGILSAAMSTLASSINSLAASTVTDLIKGKASLSTSRLISVAWAAVLIGIALVFNENDKAIVMLGLEIASFTYGGLL
GLFLLSKSSRNFHSTSLIAGLLASMAVVFLLKLLGLAWTWYIAVSVTTNILTTAGVEALLPDRESFARE

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=426, Percent_Identity=28.6384976525822, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI167466278, Length=450, Percent_Identity=28.2222222222222, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI256985183, Length=450, Percent_Identity=27.3333333333333, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI157671931, Length=343, Percent_Identity=29.1545189504373, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI4507033, Length=387, Percent_Identity=25.3229974160207, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI110835708, Length=424, Percent_Identity=23.5849056603774, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4507031, Length=416, Percent_Identity=22.8365384615385, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI206597483, Length=392, Percent_Identity=24.234693877551, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI17941285, Length=382, Percent_Identity=23.5602094240838, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI206597487, Length=311, Percent_Identity=25.4019292604502, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI109659839, Length=431, Percent_Identity=22.0417633410673, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14140236, Length=398, Percent_Identity=21.608040201005, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI109659836, Length=415, Percent_Identity=22.6506024096386, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790113, Length=339, Percent_Identity=24.4837758112094, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115533094, Length=379, Percent_Identity=29.5514511873351, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566512, Length=278, Percent_Identity=23.3812949640288, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573698, Length=454, Percent_Identity=26.8722466960352, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24651741, Length=472, Percent_Identity=23.9406779661017, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645928, Length=422, Percent_Identity=28.6729857819905, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24651739, Length=423, Percent_Identity=23.6406619385343, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI281362918, Length=421, Percent_Identity=23.0403800475059, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221459584, Length=402, Percent_Identity=27.6119402985075, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221459588, Length=420, Percent_Identity=27.3809523809524, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24650192, Length=406, Percent_Identity=26.3546798029557, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI221459586, Length=430, Percent_Identity=26.2790697674419, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281362054, Length=468, Percent_Identity=25.8547008547009, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362052, Length=468, Percent_Identity=25.8547008547009, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362050, Length=468, Percent_Identity=25.8547008547009, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648056, Length=468, Percent_Identity=25.8547008547009, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356827, Length=468, Percent_Identity=25.8547008547009, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641117, Length=454, Percent_Identity=24.6696035242291, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24640370, Length=435, Percent_Identity=25.0574712643678, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28574994, Length=453, Percent_Identity=24.9448123620309, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI161076631, Length=345, Percent_Identity=27.2463768115942, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281364280, Length=366, Percent_Identity=25.1366120218579, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19920916, Length=395, Percent_Identity=26.3291139240506, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221379702, Length=405, Percent_Identity=23.4567901234568, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 50112; Mature: 50112

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLDYAIIILFLAGNMMLGLWQGRSNKQTSDYFLGGHKLPWFAVMLSIVATETSVLTFV
CCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEE
SVPGLAYRGDWSFLQLAFGYIVGRILVSFILLPTYFKHGVTSIYEVIGMRFGHGIQKTAS
ECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VIFLITRILGDGIRFLATGVVVQAVTGWPLSLSVLVIGIVTLVYTISGGLKTVVWLDSIQ
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
FGLYLGGGVIAIAFILARLDAPLPDLLAPLLAAGKLKIIDTDPHIFTNPLSFVSAFSGGI
HHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCHH
LLSLCSHGVDYLMVQRVLGCDGLGSARKAMIASGVFVLFQFALFLLAGSLIYVFFHGAPL
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VKDREFTSFIVRALPAGLKGLLLAGILSAAMSTLASSINSLAASTVTDLIKGKASLSTSR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LISVAWAAVLIGIALVFNENDKAIVMLGLEIASFTYGGLLGLFLLSKSSRNFHSTSLIAG
HHHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LLASMAVVFLLKLLGLAWTWYIAVSVTTNILTTAGVEALLPDRESFARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCC
>Mature Secondary Structure
MQPLDYAIIILFLAGNMMLGLWQGRSNKQTSDYFLGGHKLPWFAVMLSIVATETSVLTFV
CCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEE
SVPGLAYRGDWSFLQLAFGYIVGRILVSFILLPTYFKHGVTSIYEVIGMRFGHGIQKTAS
ECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VIFLITRILGDGIRFLATGVVVQAVTGWPLSLSVLVIGIVTLVYTISGGLKTVVWLDSIQ
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
FGLYLGGGVIAIAFILARLDAPLPDLLAPLLAAGKLKIIDTDPHIFTNPLSFVSAFSGGI
HHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCHH
LLSLCSHGVDYLMVQRVLGCDGLGSARKAMIASGVFVLFQFALFLLAGSLIYVFFHGAPL
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VKDREFTSFIVRALPAGLKGLLLAGILSAAMSTLASSINSLAASTVTDLIKGKASLSTSR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LISVAWAAVLIGIALVFNENDKAIVMLGLEIASFTYGGLLGLFLLSKSSRNFHSTSLIAG
HHHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LLASMAVVFLLKLLGLAWTWYIAVSVTTNILTTAGVEALLPDRESFARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]