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The map label for this gene is cirA [H]

Identifier: 21674765

GI number: 21674765

Start: 1843328

End: 1845862

Strand: Direct

Name: cirA [H]

Synonym: CT1953

Alternate gene names: 21674765

Gene position: 1843328-1845862 (Clockwise)

Preceding gene: 21674764

Following gene: 21674767

Centisome position: 85.54

GC content: 52.78

Gene sequence:

>2535_bases
ATGAAAAAGCAGCAGGCAAAGGGTTCTGGCATGAAAAGGCTCGCGCTTTCGGCGACCTTTCTTGCAACAACGCTGGCTCC
AGTGACAACCTGGGGTGCGGATGGCGTCATCCGGGGACGCGTCACGGACAAGGCAGACGGTGAAGGCGTCGTCGGCGCCG
CAGTATCGATCGCCGGCACCAACATCGCAACCGCCACAGACATCAACGGCAACTTCGTGCTCCGGAACGTTCCTGCCTCG
AAACAGCAGAAAGTCATCGTGACCAGCATCGGTTACGCGCCAACGACGCAGGTCATCAACCTCGGCGATGGCCAGACCGC
CACGCTGAATATCGCTCTCGGCCAGACCACCATCATGGCCTCGGAAGTGGTTGTCGGCGCCGCGCTGTACAAGCAGGACA
GGCTTGACGTGCCGGTTACCGCTAACATTGTCACCAAAGAGCAGATCAGGGAAGAACCAAATCCGACACTCGATGAAGTG
GTGCAAGACGTGCCCGGCGTCGTGGTCAGTCGCGCTGGCGGAACCTCGTCATCGAACTTGCAGATTCGCGGATCGAATAC
CTACAATGGCGGCGGTATTGGCACCAGGGTGAACGCTTTCTACGACGGCTTCCCGATCAACAGCCCGGACAGCGGCGAAA
TCGTCTGGCAATCGGTCAACATGAATGCTGCCGACAAGGTCGAGGTGCTCAAGGGCGCAGCCGCAACGCTCTACGGTTCC
GGAGCCATGGGCGGCGTAGTGAACATCACGGGCCATTTGCCAGACAAATTTGAAGTCAAGGCGGGAAGCGGCATCGGCTT
TTACGACAAAACGCCATCGAGCGATGAGAGCGAATATCGCAAAGGCTTCACCCCGGTATTCTGGAACACCTATGCCGGTT
TCGGAAACAAGTCCGGCAAATGGACATACGACTTCCTTTACTCGCACAGCGATGACGACGGCTACCGCCAAAACGCCTGG
AATTACATGAACGACGTCAAGTTCAAAGCACGGTACGACATCGATTCAAGGCAATACTTGCAGCTCACTTCGTTCTACAA
CTCGACGGTCGGCGGCTATGCGTACCAGTGGCCTTACAATGCGACAATATCGACATCCACATTCACCCCAATTCTCGATC
AATCGTATGATGTATTTGTAAATGCCAGATTGTTTCCCACCCACACGGCGGCATTCTCGTACGCTCAAACCATGTATCCT
ACTAGCCCTTTTCTATGGGATATACTTGCAAATGCCTGGTCAACGTATACAAAATACGACGTCTATACCGATGACTTGAT
CAGCCGGAAAAACGCTCTGGTAGGCATCAATTATGTCAACCTGCTCAGCGACAAGCTGTCACTCGACACTCGTCTGTATT
ACACCTACAATGCCTCGCGAATCGAGTACAACCGCACTGATGCTGATCAGACATACGCAACCGGCAGAATCAGAACTATC
GGCGAGTTCAATGAAACGGATGACAGCCGCTATGGCGCAGGGATAAAACTCGATTGGCGTGCCAGCGATAACCATCGCCT
TCTGTTTGGTGTGGACGGCAATATCGTTGACACAAGAACAACTCAGGTTGCTGTGGAATATCCGGTAAAAAACGAGTTCA
ACAACATCCAGGAAAAGAATTTTGCTGTCTTCCTGCAAGACGAGTGGAAAATCACTGACAAGCTGACTTCACTGATGTCG
TTGCGCTATGACTGGAGCGGTGTCAACAAAGATGAAGTAGAGATAACCCCGGGAGTCTGGATACCCATTAACAAAAAAAG
CGTTGATGCCTTAAGCCCAAGGGTCGCCTTAAACTACAGAGCAACCGACGACATGGCACTTCGCGCATCTTGGGGCCGTA
GTTTCCGTGCCCCGTCTTTATATGAGCGGTTCGTGCATGATGCGGGATTCCTGACCGTTGTACCAAATCCAGACCTTGAC
AAGGAAACCATGACAGCATGGGAGGCTGGCATTTTCAAGCAGTTCAGCGATAAAGTCTCACTCGACATCGCCGGGTTTAT
CAACAACTATGATAACCTTATCGAGTCGCGGCCTACCGCTGCTCCATTAACCTACATGTATGGCAACATAACCAAAGCTC
GCATCTGGGGTATTGAGACAAACCTGAACTACAGACCAAACACAGACTGGAACCTGAGCGTGGGCTATACCTACATGAAT
GCAAAAAACCGTTCGTTCGATGCATCAACGGCCACCGCTACAGAACTGAACAACCCCGATCCGGAATGGCTGCCCTATCG
GCCTGAGCACACGGCTTCGGCCAGCGTGACCTGGAAAGCAACCAAAAAACTGACTCTGAATGTCAACGGGCGTTACGTCG
GCAAGTACAAGGCTGTCACCTTGTACACCAATCCTGATGGCAAGTGGTATCCCGGCGATTTCGTGGTGTTCAACGCTGGC
TTGAAGTACCAGTTCAACAAGAACGTCACAGCCACACTGGCCTGCAACAACATCAACAACACACAGTACAGTGAGGCTGA
GTGGTTCCGCGCTCCGAACCGCAGCTTCATCGCCGGTATCGATCTGACGTACTGA

Upstream 100 bases:

>100_bases
GCGCCGATGAGCAACAGCGGATCGCAACAATCAACCACTGTCCGCTGGAAAGCTATGTCCTACAACGCTCAGACAACACA
AACAACCCAATACTCACATT

Downstream 100 bases:

>100_bases
TCGATCAAAACATCGTCTCGCCGCCAGCTCGGCACAAAAACGGAAGGGCTGTCACTGTGGCAGCCCTTCCGTTTTGTCTT
CTCGTAACCATTAACATCAC

Product: ferric siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MKKQQAKGSGMKRLALSATFLATTLAPVTTWGADGVIRGRVTDKADGEGVVGAAVSIAGTNIATATDINGNFVLRNVPAS
KQQKVIVTSIGYAPTTQVINLGDGQTATLNIALGQTTIMASEVVVGAALYKQDRLDVPVTANIVTKEQIREEPNPTLDEV
VQDVPGVVVSRAGGTSSSNLQIRGSNTYNGGGIGTRVNAFYDGFPINSPDSGEIVWQSVNMNAADKVEVLKGAAATLYGS
GAMGGVVNITGHLPDKFEVKAGSGIGFYDKTPSSDESEYRKGFTPVFWNTYAGFGNKSGKWTYDFLYSHSDDDGYRQNAW
NYMNDVKFKARYDIDSRQYLQLTSFYNSTVGGYAYQWPYNATISTSTFTPILDQSYDVFVNARLFPTHTAAFSYAQTMYP
TSPFLWDILANAWSTYTKYDVYTDDLISRKNALVGINYVNLLSDKLSLDTRLYYTYNASRIEYNRTDADQTYATGRIRTI
GEFNETDDSRYGAGIKLDWRASDNHRLLFGVDGNIVDTRTTQVAVEYPVKNEFNNIQEKNFAVFLQDEWKITDKLTSLMS
LRYDWSGVNKDEVEITPGVWIPINKKSVDALSPRVALNYRATDDMALRASWGRSFRAPSLYERFVHDAGFLTVVPNPDLD
KETMTAWEAGIFKQFSDKVSLDIAGFINNYDNLIESRPTAAPLTYMYGNITKARIWGIETNLNYRPNTDWNLSVGYTYMN
AKNRSFDASTATATELNNPDPEWLPYRPEHTASASVTWKATKKLTLNVNGRYVGKYKAVTLYTNPDGKWYPGDFVVFNAG
LKYQFNKNVTATLACNNINNTQYSEAEWFRAPNRSFIAGIDLTY

Sequences:

>Translated_844_residues
MKKQQAKGSGMKRLALSATFLATTLAPVTTWGADGVIRGRVTDKADGEGVVGAAVSIAGTNIATATDINGNFVLRNVPAS
KQQKVIVTSIGYAPTTQVINLGDGQTATLNIALGQTTIMASEVVVGAALYKQDRLDVPVTANIVTKEQIREEPNPTLDEV
VQDVPGVVVSRAGGTSSSNLQIRGSNTYNGGGIGTRVNAFYDGFPINSPDSGEIVWQSVNMNAADKVEVLKGAAATLYGS
GAMGGVVNITGHLPDKFEVKAGSGIGFYDKTPSSDESEYRKGFTPVFWNTYAGFGNKSGKWTYDFLYSHSDDDGYRQNAW
NYMNDVKFKARYDIDSRQYLQLTSFYNSTVGGYAYQWPYNATISTSTFTPILDQSYDVFVNARLFPTHTAAFSYAQTMYP
TSPFLWDILANAWSTYTKYDVYTDDLISRKNALVGINYVNLLSDKLSLDTRLYYTYNASRIEYNRTDADQTYATGRIRTI
GEFNETDDSRYGAGIKLDWRASDNHRLLFGVDGNIVDTRTTQVAVEYPVKNEFNNIQEKNFAVFLQDEWKITDKLTSLMS
LRYDWSGVNKDEVEITPGVWIPINKKSVDALSPRVALNYRATDDMALRASWGRSFRAPSLYERFVHDAGFLTVVPNPDLD
KETMTAWEAGIFKQFSDKVSLDIAGFINNYDNLIESRPTAAPLTYMYGNITKARIWGIETNLNYRPNTDWNLSVGYTYMN
AKNRSFDASTATATELNNPDPEWLPYRPEHTASASVTWKATKKLTLNVNGRYVGKYKAVTLYTNPDGKWYPGDFVVFNAG
LKYQFNKNVTATLACNNINNTQYSEAEWFRAPNRSFIAGIDLTY
>Mature_844_residues
MKKQQAKGSGMKRLALSATFLATTLAPVTTWGADGVIRGRVTDKADGEGVVGAAVSIAGTNIATATDINGNFVLRNVPAS
KQQKVIVTSIGYAPTTQVINLGDGQTATLNIALGQTTIMASEVVVGAALYKQDRLDVPVTANIVTKEQIREEPNPTLDEV
VQDVPGVVVSRAGGTSSSNLQIRGSNTYNGGGIGTRVNAFYDGFPINSPDSGEIVWQSVNMNAADKVEVLKGAAATLYGS
GAMGGVVNITGHLPDKFEVKAGSGIGFYDKTPSSDESEYRKGFTPVFWNTYAGFGNKSGKWTYDFLYSHSDDDGYRQNAW
NYMNDVKFKARYDIDSRQYLQLTSFYNSTVGGYAYQWPYNATISTSTFTPILDQSYDVFVNARLFPTHTAAFSYAQTMYP
TSPFLWDILANAWSTYTKYDVYTDDLISRKNALVGINYVNLLSDKLSLDTRLYYTYNASRIEYNRTDADQTYATGRIRTI
GEFNETDDSRYGAGIKLDWRASDNHRLLFGVDGNIVDTRTTQVAVEYPVKNEFNNIQEKNFAVFLQDEWKITDKLTSLMS
LRYDWSGVNKDEVEITPGVWIPINKKSVDALSPRVALNYRATDDMALRASWGRSFRAPSLYERFVHDAGFLTVVPNPDLD
KETMTAWEAGIFKQFSDKVSLDIAGFINNYDNLIESRPTAAPLTYMYGNITKARIWGIETNLNYRPNTDWNLSVGYTYMN
AKNRSFDASTATATELNNPDPEWLPYRPEHTASASVTWKATKKLTLNVNGRYVGKYKAVTLYTNPDGKWYPGDFVVFNAG
LKYQFNKNVTATLACNNINNTQYSEAEWFRAPNRSFIAGIDLTY

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=338, Percent_Identity=26.3313609467456, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 93822; Mature: 93822

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQQAKGSGMKRLALSATFLATTLAPVTTWGADGVIRGRVTDKADGEGVVGAAVSIAGT
CCCCCCCCCCCEEHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCEEEEEEEEECC
NIATATDINGNFVLRNVPASKQQKVIVTSIGYAPTTQVINLGDGQTATLNIALGQTTIMA
CEEEEEECCCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEECCEEEEH
SEVVVGAALYKQDRLDVPVTANIVTKEQIREEPNPTLDEVVQDVPGVVVSRAGGTSSSNL
HHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCCCEE
QIRGSNTYNGGGIGTRVNAFYDGFPINSPDSGEIVWQSVNMNAADKVEVLKGAAATLYGS
EEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCEEEEECC
GAMGGVVNITGHLPDKFEVKAGSGIGFYDKTPSSDESEYRKGFTPVFWNTYAGFGNKSGK
CCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCCC
WTYDFLYSHSDDDGYRQNAWNYMNDVKFKARYDIDSRQYLQLTSFYNSTVGGYAYQWPYN
EEEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCEEEEEHHHCCCCCCEEEECCCC
ATISTSTFTPILDQSYDVFVNARLFPTHTAAFSYAQTMYPTSPFLWDILANAWSTYTKYD
CEEECCCCCHHHCCCCEEEEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEE
VYTDDLISRKNALVGINYVNLLSDKLSLDTRLYYTYNASRIEYNRTDADQTYATGRIRTI
EECHHHHCCCCCEEEEEHHHHHHHHHCCCEEEEEEEECCEEEECCCCCCCEEECCEEEEE
GEFNETDDSRYGAGIKLDWRASDNHRLLFGVDGNIVDTRTTQVAVEYPVKNEFNNIQEKN
CCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCEEECCEEEEEEECCCCCCCCCCCCCC
FAVFLQDEWKITDKLTSLMSLRYDWSGVNKDEVEITPGVWIPINKKSVDALSPRVALNYR
EEEEEECCCCHHHHHHHHHHEEECCCCCCCCCEEECCCEEEEECCCCCHHCCCEEEEEEE
ATDDMALRASWGRSFRAPSLYERFVHDAGFLTVVPNPDLDKETMTAWEAGIFKQFSDKVS
CCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCEE
LDIAGFINNYDNLIESRPTAAPLTYMYGNITKARIWGIETNLNYRPNTDWNLSVGYTYMN
EEEEEHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCCEEEEEEEEEC
AKNRSFDASTATATELNNPDPEWLPYRPEHTASASVTWKATKKLTLNVNGRYVGKYKAVT
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCEEEEEEEEEE
LYTNPDGKWYPGDFVVFNAGLKYQFNKNVTATLACNNINNTQYSEAEWFRAPNRSFIAGI
EEECCCCCEECCCEEEEECCEEEEECCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEEE
DLTY
EECC
>Mature Secondary Structure
MKKQQAKGSGMKRLALSATFLATTLAPVTTWGADGVIRGRVTDKADGEGVVGAAVSIAGT
CCCCCCCCCCCEEHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCEEEEEEEEECC
NIATATDINGNFVLRNVPASKQQKVIVTSIGYAPTTQVINLGDGQTATLNIALGQTTIMA
CEEEEEECCCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEECCEEEEH
SEVVVGAALYKQDRLDVPVTANIVTKEQIREEPNPTLDEVVQDVPGVVVSRAGGTSSSNL
HHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCCCEE
QIRGSNTYNGGGIGTRVNAFYDGFPINSPDSGEIVWQSVNMNAADKVEVLKGAAATLYGS
EEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCEEEEECC
GAMGGVVNITGHLPDKFEVKAGSGIGFYDKTPSSDESEYRKGFTPVFWNTYAGFGNKSGK
CCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCCC
WTYDFLYSHSDDDGYRQNAWNYMNDVKFKARYDIDSRQYLQLTSFYNSTVGGYAYQWPYN
EEEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCEEEEEHHHCCCCCCEEEECCCC
ATISTSTFTPILDQSYDVFVNARLFPTHTAAFSYAQTMYPTSPFLWDILANAWSTYTKYD
CEEECCCCCHHHCCCCEEEEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEE
VYTDDLISRKNALVGINYVNLLSDKLSLDTRLYYTYNASRIEYNRTDADQTYATGRIRTI
EECHHHHCCCCCEEEEEHHHHHHHHHCCCEEEEEEEECCEEEECCCCCCCEEECCEEEEE
GEFNETDDSRYGAGIKLDWRASDNHRLLFGVDGNIVDTRTTQVAVEYPVKNEFNNIQEKN
CCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCEEECCEEEEEEECCCCCCCCCCCCCC
FAVFLQDEWKITDKLTSLMSLRYDWSGVNKDEVEITPGVWIPINKKSVDALSPRVALNYR
EEEEEECCCCHHHHHHHHHHEEECCCCCCCCCEEECCCEEEEECCCCCHHCCCEEEEEEE
ATDDMALRASWGRSFRAPSLYERFVHDAGFLTVVPNPDLDKETMTAWEAGIFKQFSDKVS
CCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCEE
LDIAGFINNYDNLIESRPTAAPLTYMYGNITKARIWGIETNLNYRPNTDWNLSVGYTYMN
EEEEEHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCCEEEEEEEEEC
AKNRSFDASTATATELNNPDPEWLPYRPEHTASASVTWKATKKLTLNVNGRYVGKYKAVT
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCEEEEEEEEEE
LYTNPDGKWYPGDFVVFNAGLKYQFNKNVTATLACNNINNTQYSEAEWFRAPNRSFIAGI
EEECCCCCEECCCEEEEECCEEEEECCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEEE
DLTY
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]