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The map label for this gene is acpS

Identifier: 21674747

GI number: 21674747

Start: 1829662

End: 1830015

Strand: Reverse

Name: acpS

Synonym: CT1935

Alternate gene names: 21674747

Gene position: 1830015-1829662 (Counterclockwise)

Preceding gene: 21674748

Following gene: 21674745

Centisome position: 84.92

GC content: 56.78

Gene sequence:

>354_bases
ATGGAGATCGGGGTTGACATCGTCGAGATAGCTCGTATCCGTTCGAGTTATGACCGTTTCGGAGAGGCCTTCATGAAGAA
AATTCTGACCTCGGCCGAGATGGCCCAGTGCCTTTCCAAACCCGATCCCGTGGCGAGCCTTGCCGGACGTTTTGCAGCCA
AAGAGGCTGTTTCGAAAGCTCTCGGTACTGGCATCGCCAAAGGCCTGACCTGGCACTCCATCGAGGTGTTGAACGACGAG
ACGGGCAAACCCTGTGTGAGCGTTTACGCGCCCTCCTTTTCCGGTAGAGTCAGTATTTCAATCTCCCACGACCGCTACTC
CGCAGTGGCGATGGCGCTCTTTGAGCCGCGCTGA

Upstream 100 bases:

>100_bases
TCGCCATGACCGGCGTCGATTTTATTTCAATCGGCGAGCTGACTCATAGCGTCAAGGCGCTCGATATGTCCATGAAGATC
GAACGTGCCTGATCCCGTCG

Downstream 100 bases:

>100_bases
GCATCCGGCAATTTCCCCGTCGCGCATAAAAAAAGGCTCATCAGTCGATGAGCCTTTTTGCTTCAGAAAGCCTTATTTTT
CGATTACTTCAGTTGTGCGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MEIGVDIVEIARIRSSYDRFGEAFMKKILTSAEMAQCLSKPDPVASLAGRFAAKEAVSKALGTGIAKGLTWHSIEVLNDE
TGKPCVSVYAPSFSGRVSISISHDRYSAVAMALFEPR

Sequences:

>Translated_117_residues
MEIGVDIVEIARIRSSYDRFGEAFMKKILTSAEMAQCLSKPDPVASLAGRFAAKEAVSKALGTGIAKGLTWHSIEVLNDE
TGKPCVSVYAPSFSGRVSISISHDRYSAVAMALFEPR
>Mature_117_residues
MEIGVDIVEIARIRSSYDRFGEAFMKKILTSAEMAQCLSKPDPVASLAGRFAAKEAVSKALGTGIAKGLTWHSIEVLNDE
TGKPCVSVYAPSFSGRVSISISHDRYSAVAMALFEPR

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=120, Percent_Identity=36.6666666666667, Blast_Score=83, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CHLTE (Q8KB56)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662812.1
- ProteinModelPortal:   Q8KB56
- SMR:   Q8KB56
- GeneID:   1008257
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1935
- NMPDR:   fig|194439.1.peg.1906
- TIGR:   CT1935
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   CTEP194439:CT_1935-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 12611; Mature: 12611

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGVDIVEIARIRSSYDRFGEAFMKKILTSAEMAQCLSKPDPVASLAGRFAAKEAVSKA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LGTGIAKGLTWHSIEVLNDETGKPCVSVYAPSFSGRVSISISHDRYSAVAMALFEPR
HHHHHHCCCCHHHEEEECCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure
MEIGVDIVEIARIRSSYDRFGEAFMKKILTSAEMAQCLSKPDPVASLAGRFAAKEAVSKA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LGTGIAKGLTWHSIEVLNDETGKPCVSVYAPSFSGRVSISISHDRYSAVAMALFEPR
HHHHHHCCCCHHHEEEECCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901