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The map label for this gene is dapB

Identifier: 21674663

GI number: 21674663

Start: 1749863

End: 1750612

Strand: Reverse

Name: dapB

Synonym: CT1850

Alternate gene names: 21674663

Gene position: 1750612-1749863 (Counterclockwise)

Preceding gene: 21674664

Following gene: 21674662

Centisome position: 81.24

GC content: 58.4

Gene sequence:

>750_bases
ATGAAGATCACACTGGTCGGCAATGGCCGCATGGGCCGTCAGATAGCCGACGTCGTTGCCGCCTCGGGTGCACATGTCGT
CAACCGTGTGCTCGATGTCAACGACACCATCGATGCCGCTGCGTTCAGCGGGTCGGACGTTATTATCGATTTTACCGTCA
GGAGTGCATTTCTCGCCAACTATCCGGCGCTGATTGCCTCCGGTGTGCCGGTCGTGGTGGGCACCACTGGCTGGGACGAC
GTGATGCCGCAGGTTCGCGAAGAGGTCGTAAAGGCTAGGAGCACAATGCTCTATTCAGCGAACTACTCGCTTGGCGTCAA
CATCTTTTTCCGGACGCTGCGCGAGGCCGCGCGCCTGATTGCGCCGTTTGAGCAGTTCGATATCGCGCTTTCGGAGCAGC
ACCATACCGGCAAGGCGGACTTCCCGAGCGGCACGGCGATCAAGGCTGCCGATGAGATTCTGAACTCCAATCCCCGCAAG
CGAACTATCGTTCGCGAGCTTCAGGAGGGCAGGAAATTGCAGAGCGACGAATTGCAGGTCGCCTCGATCCGCCTTGGCTC
TGTGTTCGGGGTGCATTCCGCGATTATCGATTCGGAATCGGACACCATCGAACTGACTCACACGGCCAAGAACCGCACCG
GTTTCGCTTCCGGGGCAGTTCGTGCCGCAGAGTGGCTTGTTCAGCGCCACGCTACGTCGCCGGGCTTCTACACGATGGAT
GATTTTCTAAACGATCTTTTTTCTGCCTGA

Upstream 100 bases:

>100_bases
ATCAAATATTTTTCAGGCGAAGATCTCGACCGGATACTCGAACTGATCGGTCAGTGAGTGCCTGGAGCAATTACCAGAAG
TACAAAAACAAGCTGAGATT

Downstream 100 bases:

>100_bases
AATGGTCGTCGAAACTGTGCCGGGTCGTCCATCGAAAGTATCGGCGCTGCTCGGCGGCGCGGTGCTGCTCGTGCTGACGA
CGACGCTGCCCTATCTGACC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKITLVGNGRMGRQIADVVAASGAHVVNRVLDVNDTIDAAAFSGSDVIIDFTVRSAFLANYPALIASGVPVVVGTTGWDD
VMPQVREEVVKARSTMLYSANYSLGVNIFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAADEILNSNPRK
RTIVRELQEGRKLQSDELQVASIRLGSVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLVQRHATSPGFYTMD
DFLNDLFSA

Sequences:

>Translated_249_residues
MKITLVGNGRMGRQIADVVAASGAHVVNRVLDVNDTIDAAAFSGSDVIIDFTVRSAFLANYPALIASGVPVVVGTTGWDD
VMPQVREEVVKARSTMLYSANYSLGVNIFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAADEILNSNPRK
RTIVRELQEGRKLQSDELQVASIRLGSVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLVQRHATSPGFYTMD
DFLNDLFSA
>Mature_249_residues
MKITLVGNGRMGRQIADVVAASGAHVVNRVLDVNDTIDAAAFSGSDVIIDFTVRSAFLANYPALIASGVPVVVGTTGWDD
VMPQVREEVVKARSTMLYSANYSLGVNIFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAADEILNSNPRK
RTIVRELQEGRKLQSDELQVASIRLGSVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLVQRHATSPGFYTMD
DFLNDLFSA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=203, Percent_Identity=32.0197044334975, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHLTE (Q8KBD8)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662728.1
- HSSP:   Q9X1K8
- ProteinModelPortal:   Q8KBD8
- SMR:   Q8KBD8
- GeneID:   1007881
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1850
- NMPDR:   fig|194439.1.peg.1822
- TIGR:   CT1850
- HOGENOM:   HBG594002
- OMA:   KYLAKIM
- ProtClustDB:   CLSK637968
- BioCyc:   CTEP194439:CT_1850-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27028; Mature: 27028

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLVGNGRMGRQIADVVAASGAHVVNRVLDVNDTIDAAAFSGSDVIIDFTVRSAFLAN
CEEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHEECCCCEEEEEHHHHHHHHC
YPALIASGVPVVVGTTGWDDVMPQVREEVVKARSTMLYSANYSLGVNIFFRTLREAARLI
CHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHH
APFEQFDIALSEQHHTGKADFPSGTAIKAADEILNSNPRKRTIVRELQEGRKLQSDELQV
CCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEE
ASIRLGSVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLVQRHATSPGFYTMD
EEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHH
DFLNDLFSA
HHHHHHHCC
>Mature Secondary Structure
MKITLVGNGRMGRQIADVVAASGAHVVNRVLDVNDTIDAAAFSGSDVIIDFTVRSAFLAN
CEEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHEECCCCEEEEEHHHHHHHHC
YPALIASGVPVVVGTTGWDDVMPQVREEVVKARSTMLYSANYSLGVNIFFRTLREAARLI
CHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHH
APFEQFDIALSEQHHTGKADFPSGTAIKAADEILNSNPRKRTIVRELQEGRKLQSDELQV
CCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEE
ASIRLGSVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLVQRHATSPGFYTMD
EEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHH
DFLNDLFSA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901