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The map label for this gene is hypE [H]

Identifier: 21674606

GI number: 21674606

Start: 1697490

End: 1698533

Strand: Reverse

Name: hypE [H]

Synonym: CT1792

Alternate gene names: 21674606

Gene position: 1698533-1697490 (Counterclockwise)

Preceding gene: 21674607

Following gene: 21674605

Centisome position: 78.82

GC content: 67.43

Gene sequence:

>1044_bases
ATGACCATGCAACTGAGCTGCCCTTCGCCGATTCTTCGGCATGAAACCGTCCAGATGGCTCATGGTGCGGGCGGGCGTTT
GTCGCAGGAGCTGACGGCGCGGGTGTTCATGCCGCATCTCGGCAATCCGGTGCTCGACCAGCTCGACGACCAGGCGCGGT
TCGAGGCCGAGCCGGGGCGCATCGCCTTTACCACCGACACCTACGTCGTCTCGCCGATCTTTTTTCCCGGCGGGAACATC
GGTGACCTCGCGGTTAACGGCACGGTGAACGACCTCGCCGTCGGCGGCGCCGTGCCGCGCTACCTCAGCGCCGGGTTCGT
GCTCGAAGAGGGGCTGCCGCTCTCGGAGCTCGAACGGATCGTCAAAAGCATGGCCGACGCCGCGCGGAAGGCCGGGGTGG
TCATCGCGTGCGGCGACACCAAAGTGGTGCAGAAAGGGCAGTGCGACCGGATTTTCATCAACACCTCCGGCGTCGGCTTC
ATCCCGCCGGGCCGCGACGTGTCGTGCCGCAACCTCCGCCCCGGCGATGCGGTGCTGCTTTCCGGCACCATCGGCGACCA
CGGCATGGCGATCCTCACCACCCGCGAGGGCCTCTCTTTCCAGAGCCGCATCCAGAGCGACTCCGCCGCCCTGAACGGCA
TGATCGCCGACCTGCTCGCCGCCGCGCCAAACCTCCACGCCATGCGCGACCCCACTCGCGGCGGCGTGGCGGCCACGCTC
AACGAACTCGCCTTATCGTCATCGGTCGGCATCGAACTCGACGAAGCCACAATCCCCGTGCGCGAAGAGGTGCGCGGAGC
CGCCGAACTGCTCGGCATCGACCCGCTCGCCGTTGCCAACGAAGGCAAAATGCTCGTTGTCGTTCCCGCCGCCGAAGCCG
ACGCGGCGCTCGCCGCCATGCGCTTGCACGAGCATGGACGCGAGGCCGCCGTCATCGGCAAGGTCACCGAAGAGCACCCC
GGCATGGTGGTGATGCGCACGCCCTTCGGCAGCCGCCGCATTGTCGAAATGCCCCTCGGCGAGCAGTTGCCGCGGATTTG
CTGA

Upstream 100 bases:

>100_bases
GCTTGCGATAATGGGAATCAAAAGGGGTGCGATAATTACCGAAGGCTGAATGAACTGGGATACTAACACTTTCGATATGT
CCTTTCATTCCAATTCACCA

Downstream 100 bases:

>100_bases
GGGTGGACGGCGTGGACATGGTGGGCAAAGAACGGCACTCGATATTCTTTCTTTGCCTTTTGAGCCATTGTTGCCTTTGA
CGTCTCTGTTTTGCATCGGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTMQLSCPSPILRHETVQMAHGAGGRLSQELTARVFMPHLGNPVLDQLDDQARFEAEPGRIAFTTDTYVVSPIFFPGGNI
GDLAVNGTVNDLAVGGAVPRYLSAGFVLEEGLPLSELERIVKSMADAARKAGVVIACGDTKVVQKGQCDRIFINTSGVGF
IPPGRDVSCRNLRPGDAVLLSGTIGDHGMAILTTREGLSFQSRIQSDSAALNGMIADLLAAAPNLHAMRDPTRGGVAATL
NELALSSSVGIELDEATIPVREEVRGAAELLGIDPLAVANEGKMLVVVPAAEADAALAAMRLHEHGREAAVIGKVTEEHP
GMVVMRTPFGSRRIVEMPLGEQLPRIC

Sequences:

>Translated_347_residues
MTMQLSCPSPILRHETVQMAHGAGGRLSQELTARVFMPHLGNPVLDQLDDQARFEAEPGRIAFTTDTYVVSPIFFPGGNI
GDLAVNGTVNDLAVGGAVPRYLSAGFVLEEGLPLSELERIVKSMADAARKAGVVIACGDTKVVQKGQCDRIFINTSGVGF
IPPGRDVSCRNLRPGDAVLLSGTIGDHGMAILTTREGLSFQSRIQSDSAALNGMIADLLAAAPNLHAMRDPTRGGVAATL
NELALSSSVGIELDEATIPVREEVRGAAELLGIDPLAVANEGKMLVVVPAAEADAALAAMRLHEHGREAAVIGKVTEEHP
GMVVMRTPFGSRRIVEMPLGEQLPRIC
>Mature_346_residues
TMQLSCPSPILRHETVQMAHGAGGRLSQELTARVFMPHLGNPVLDQLDDQARFEAEPGRIAFTTDTYVVSPIFFPGGNIG
DLAVNGTVNDLAVGGAVPRYLSAGFVLEEGLPLSELERIVKSMADAARKAGVVIACGDTKVVQKGQCDRIFINTSGVGFI
PPGRDVSCRNLRPGDAVLLSGTIGDHGMAILTTREGLSFQSRIQSDSAALNGMIADLLAAAPNLHAMRDPTRGGVAATLN
ELALSSSVGIELDEATIPVREEVRGAAELLGIDPLAVANEGKMLVVVPAAEADAALAAMRLHEHGREAAVIGKVTEEHPG
MVVMRTPFGSRRIVEMPLGEQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=48.5207100591716, Blast_Score=316, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36594; Mature: 36462

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMQLSCPSPILRHETVQMAHGAGGRLSQELTARVFMPHLGNPVLDQLDDQARFEAEPGR
CEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCCCCE
IAFTTDTYVVSPIFFPGGNIGDLAVNGTVNDLAVGGAVPRYLSAGFVLEEGLPLSELERI
EEEEECCEEEEEEEECCCCCCCEEECCCHHHHCCCCCHHHHHHCCEEEECCCCHHHHHHH
VKSMADAARKAGVVIACGDTKVVQKGQCDRIFINTSGVGFIPPGRDVSCRNLRPGDAVLL
HHHHHHHHHHCCEEEEECCCCEECCCCCCEEEEECCCEEECCCCCCCCCCCCCCCCEEEE
SGTIGDHGMAILTTREGLSFQSRIQSDSAALNGMIADLLAAAPNLHAMRDPTRGGVAATL
ECCCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
NELALSSSVGIELDEATIPVREEVRGAAELLGIDPLAVANEGKMLVVVPAAEADAALAAM
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHHH
RLHEHGREAAVIGKVTEEHPGMVVMRTPFGSRRIVEMPLGEQLPRIC
HHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
TMQLSCPSPILRHETVQMAHGAGGRLSQELTARVFMPHLGNPVLDQLDDQARFEAEPGR
EEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCCCCE
IAFTTDTYVVSPIFFPGGNIGDLAVNGTVNDLAVGGAVPRYLSAGFVLEEGLPLSELERI
EEEEECCEEEEEEEECCCCCCCEEECCCHHHHCCCCCHHHHHHCCEEEECCCCHHHHHHH
VKSMADAARKAGVVIACGDTKVVQKGQCDRIFINTSGVGFIPPGRDVSCRNLRPGDAVLL
HHHHHHHHHHCCEEEEECCCCEECCCCCCEEEEECCCEEECCCCCCCCCCCCCCCCEEEE
SGTIGDHGMAILTTREGLSFQSRIQSDSAALNGMIADLLAAAPNLHAMRDPTRGGVAATL
ECCCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
NELALSSSVGIELDEATIPVREEVRGAAELLGIDPLAVANEGKMLVVVPAAEADAALAAM
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHHH
RLHEHGREAAVIGKVTEEHPGMVVMRTPFGSRRIVEMPLGEQLPRIC
HHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]