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The map label for this gene is tsf [H]

Identifier: 21674594

GI number: 21674594

Start: 1686322

End: 1687188

Strand: Reverse

Name: tsf [H]

Synonym: CT1780

Alternate gene names: 21674594

Gene position: 1687188-1686322 (Counterclockwise)

Preceding gene: 21674595

Following gene: 21674593

Centisome position: 78.29

GC content: 54.33

Gene sequence:

>867_bases
ATGAGCCAGATTTCTGCCAAAGACGTCAAGGAACTCAGGGATACCACCGGCGTCGGCATGATGGAGTGCAAGAAAGCCCT
CGAAGAGACCGGTGGAGACATGCAGAAAGCCGTCGAATATCTCCGCAAGAAAGGCGCCGCGATGGCAGCCAAGCGCGCTG
ATCGCGAAGCTTCCGAAGGCGTGGTTTGCATTCTGATGAGCGACGACCAGAAAACCGGTGTGATTCTGGAACTCAATTGC
GAGACCGATTTCGTGGCTCGTGGTGAAGTGTTCACCGGCTTTGCCAACGAGCTTGCCACTCTTGCCTTGTCCAACAACTG
TGAGTCGAGAGAAGATTTGCTTGGTATTAAACTTGGCGAGGCTTACGGGAACGAAACCGTTGAAGAGGCCCTCAAGTCGA
TGACCGGCAAGGTTGGTGAGAAACTCGAACTCAAACGCATGGCTCGCCTCACCGCTGAAGCAGGCGTGCTTGAAAGCTAT
ATCCACCCCGGATCCCAGCTTGGTGCGCTGATCGCTATCGATACCGACAAGCCGGCAGAGGCCAAAGCGCTCGCCAAAGA
CCTCGCCATGCAGGTGGCAGCTGCTGCACCGATCGAAGTCAGTCGTGATGCTGTGTCGACGGAACTTGTCGAAAAAGAGA
AAGAGATTTATCGTCAGCAGGCGCTTGCCGAGGGCAAGAAAGAGGAGTTCGTTGACAAGATCGTCATGGGTCGCCTCAAC
AAATACTACCAGGAGGTGGTGCTGACCGAGCAGACCTTCATCAAGGATCAGAACACCAAGGTCTCCGGCGTGCTCGACGA
CTTCATGAAGAAGAACCAGGCGCAAGTCAAGGTCAAAGCATTTGTCAGGTATCAGTTAGGAGCCTGA

Upstream 100 bases:

>100_bases
ACGGCCAACGACTAATCTTAATGTTACTGGAACGAGGCTGGAATTCCGCGCTCCAGTCTCGTTTTCCGCAACCAATCACG
ATACATACCCATAGTTTATT

Downstream 100 bases:

>100_bases
AACTGAAAAAAGCCTCGTTGACGCGAGGCTTTTTTTTGCTTATTTGAAAGTCCCGATCAGTTATGTCGCAAGAGTCAAAT
AGAAACAAGGAGAACCAGCC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEGVVCILMSDDQKTGVILELNC
ETDFVARGEVFTGFANELATLALSNNCESREDLLGIKLGEAYGNETVEEALKSMTGKVGEKLELKRMARLTAEAGVLESY
IHPGSQLGALIAIDTDKPAEAKALAKDLAMQVAAAAPIEVSRDAVSTELVEKEKEIYRQQALAEGKKEEFVDKIVMGRLN
KYYQEVVLTEQTFIKDQNTKVSGVLDDFMKKNQAQVKVKAFVRYQLGA

Sequences:

>Translated_288_residues
MSQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEGVVCILMSDDQKTGVILELNC
ETDFVARGEVFTGFANELATLALSNNCESREDLLGIKLGEAYGNETVEEALKSMTGKVGEKLELKRMARLTAEAGVLESY
IHPGSQLGALIAIDTDKPAEAKALAKDLAMQVAAAAPIEVSRDAVSTELVEKEKEIYRQQALAEGKKEEFVDKIVMGRLN
KYYQEVVLTEQTFIKDQNTKVSGVLDDFMKKNQAQVKVKAFVRYQLGA
>Mature_287_residues
SQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEGVVCILMSDDQKTGVILELNCE
TDFVARGEVFTGFANELATLALSNNCESREDLLGIKLGEAYGNETVEEALKSMTGKVGEKLELKRMARLTAEAGVLESYI
HPGSQLGALIAIDTDKPAEAKALAKDLAMQVAAAAPIEVSRDAVSTELVEKEKEIYRQQALAEGKKEEFVDKIVMGRLNK
YYQEVVLTEQTFIKDQNTKVSGVLDDFMKKNQAQVKVKAFVRYQLGA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=221, Percent_Identity=29.8642533936652, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI291084500, Length=241, Percent_Identity=28.2157676348548, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI291084498, Length=106, Percent_Identity=37.7358490566038, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI291084502, Length=106, Percent_Identity=37.7358490566038, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1786366, Length=287, Percent_Identity=38.3275261324042, Blast_Score=164, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17561440, Length=310, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19921466, Length=216, Percent_Identity=28.7037037037037, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 31545; Mature: 31413

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCC
VVCILMSDDQKTGVILELNCETDFVARGEVFTGFANELATLALSNNCESREDLLGIKLGE
EEEEEECCCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHEEECH
AYGNETVEEALKSMTGKVGEKLELKRMARLTAEAGVLESYIHPGSQLGALIAIDTDKPAE
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHH
AKALAKDLAMQVAAAAPIEVSRDAVSTELVEKEKEIYRQQALAEGKKEEFVDKIVMGRLN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KYYQEVVLTEQTFIKDQNTKVSGVLDDFMKKNQAQVKVKAFVRYQLGA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHEEHHHHHHHHCCC
>Mature Secondary Structure 
SQISAKDVKELRDTTGVGMMECKKALEETGGDMQKAVEYLRKKGAAMAAKRADREASEG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCC
VVCILMSDDQKTGVILELNCETDFVARGEVFTGFANELATLALSNNCESREDLLGIKLGE
EEEEEECCCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHEEECH
AYGNETVEEALKSMTGKVGEKLELKRMARLTAEAGVLESYIHPGSQLGALIAIDTDKPAE
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHH
AKALAKDLAMQVAAAAPIEVSRDAVSTELVEKEKEIYRQQALAEGKKEEFVDKIVMGRLN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KYYQEVVLTEQTFIKDQNTKVSGVLDDFMKKNQAQVKVKAFVRYQLGA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA