Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 21674580

GI number: 21674580

Start: 1674514

End: 1675251

Strand: Direct

Name: fabG [H]

Synonym: CT1766

Alternate gene names: 21674580

Gene position: 1674514-1675251 (Clockwise)

Preceding gene: 21674579

Following gene: 21674581

Centisome position: 77.71

GC content: 55.56

Gene sequence:

>738_bases
ATGAGCGTTTCAGGAAAAAAGGTGTGCTTCATGACCGGAGCTTCTGGCAAGCTCGGAAGTGAAATCGCACTCGCTATCGC
CGGGCAGGGCTATTCAATCTTTTTCACCTGGCAGCACTCGGAGAAGAAGGCAAAGGAAACGCTTGAAAAAATCCGCTGGG
TCAGCCCAGAATCGCAGATGGTGCGGTGCGACGTTTCGAACATCGCCGAGATCGAAAAGGCATTCGCGATCTTCAGCGAG
CACTTCAACCGCCTCGACCTGCTCATCACAAGCGCCTCAAACTTTTTCCGCACTCCCCTGCTCGACGTGACCGAACCGGA
ATGGGACAGCCTCGTCGATACCAATCTCAAAGGTGCATTCTTCACGATGCAACAGGCTTCGCGGATCATGCTGAAACAGC
CGTTCGTCTCACGCATCATCACGATGACCGATATTTCAGCAAATCTCGTTTGGCGCAACTACGCGCCGTACACGGTCTCG
AAGTCGGGCATCCAGCACCTCACGAGAATTTTCGCCAAGGAAATGGCTCCAAAAATTCTTGTCAACTCCATTGCGCCGGG
CACCATCTCGGCCTACTCCGGGCGCGACGAGGAGCCGGAAGCCGACCTTGTCGGCAAAATCCCGCTGGAGCGCCTCGGCG
ACCCGATGGACATCGTCATGGCAATCCGGTTCCTGATGGAAACCGAATACATCACCGGCCAGGTGATCAACGTGGACGGC
GGGCGGATGTTGTTCTGA

Upstream 100 bases:

>100_bases
CCCAATCCTTCTCCTCTATGCCCTACAAGTCCTATAGGATTTATAGGGCATATTTTTTATTACCTTGAAGAAAACGCCAT
CTCAACCAGCTTTTACCACC

Downstream 100 bases:

>100_bases
GCGGCGGCCCGGCTTGCCTATCCGACCGATCGGCTGGATATGTCTGATCTTGTCCCCGGCTCCGCCTTCCTCTTCCGTTA
TTTTTTTATATTCAAGCAGT

Product: 3-oxoacyl-(acyl-carrier-protein) reductase, putative

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSVSGKKVCFMTGASGKLGSEIALAIAGQGYSIFFTWQHSEKKAKETLEKIRWVSPESQMVRCDVSNIAEIEKAFAIFSE
HFNRLDLLITSASNFFRTPLLDVTEPEWDSLVDTNLKGAFFTMQQASRIMLKQPFVSRIITMTDISANLVWRNYAPYTVS
KSGIQHLTRIFAKEMAPKILVNSIAPGTISAYSGRDEEPEADLVGKIPLERLGDPMDIVMAIRFLMETEYITGQVINVDG
GRMLF

Sequences:

>Translated_245_residues
MSVSGKKVCFMTGASGKLGSEIALAIAGQGYSIFFTWQHSEKKAKETLEKIRWVSPESQMVRCDVSNIAEIEKAFAIFSE
HFNRLDLLITSASNFFRTPLLDVTEPEWDSLVDTNLKGAFFTMQQASRIMLKQPFVSRIITMTDISANLVWRNYAPYTVS
KSGIQHLTRIFAKEMAPKILVNSIAPGTISAYSGRDEEPEADLVGKIPLERLGDPMDIVMAIRFLMETEYITGQVINVDG
GRMLF
>Mature_244_residues
SVSGKKVCFMTGASGKLGSEIALAIAGQGYSIFFTWQHSEKKAKETLEKIRWVSPESQMVRCDVSNIAEIEKAFAIFSEH
FNRLDLLITSASNFFRTPLLDVTEPEWDSLVDTNLKGAFFTMQQASRIMLKQPFVSRIITMTDISANLVWRNYAPYTVSK
SGIQHLTRIFAKEMAPKILVNSIAPGTISAYSGRDEEPEADLVGKIPLERLGDPMDIVMAIRFLMETEYITGQVINVDGG
RMLF

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.1203319502075, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=28.4552845528455, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=28.3524904214559, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=25.3061224489796, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=24.0157480314961, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=25.2032520325203, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=22.7642276422764, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=25.5060728744939, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=32.6530612244898, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=28.3333333333333, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=29.7520661157025, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=27.7551020408163, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=26, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=25.7142857142857, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=27.1653543307087, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=26.7489711934156, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.953125, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=26.6129032258064, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=23.8461538461538, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=213, Percent_Identity=25.8215962441315, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=26.7206477732794, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=25.7462686567164, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=25.3846153846154, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=245, Percent_Identity=25.3061224489796, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=27.1604938271605, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=26.8482490272374, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=25.8064516129032, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=25.1028806584362, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27417; Mature: 27286

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSGKKVCFMTGASGKLGSEIALAIAGQGYSIFFTWQHSEKKAKETLEKIRWVSPESQM
CCCCCCEEEEEECCCCCCCCEEEEEEECCCEEEEEEEECCHHHHHHHHHHHHCCCCCCCE
VRCDVSNIAEIEKAFAIFSEHFNRLDLLITSASNFFRTPLLDVTEPEWDSLVDTNLKGAF
EEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHCCCCCCCCCCCHHHHHCCCCCCCE
FTMQQASRIMLKQPFVSRIITMTDISANLVWRNYAPYTVSKSGIQHLTRIFAKEMAPKIL
EEHHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHCHHHH
VNSIAPGTISAYSGRDEEPEADLVGKIPLERLGDPMDIVMAIRFLMETEYITGQVINVDG
HHCCCCCCEEECCCCCCCCCCCCEECCCHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCC
GRMLF
CEECC
>Mature Secondary Structure 
SVSGKKVCFMTGASGKLGSEIALAIAGQGYSIFFTWQHSEKKAKETLEKIRWVSPESQM
CCCCCEEEEEECCCCCCCCEEEEEEECCCEEEEEEEECCHHHHHHHHHHHHCCCCCCCE
VRCDVSNIAEIEKAFAIFSEHFNRLDLLITSASNFFRTPLLDVTEPEWDSLVDTNLKGAF
EEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHCCCCCCCCCCCHHHHHCCCCCCCE
FTMQQASRIMLKQPFVSRIITMTDISANLVWRNYAPYTVSKSGIQHLTRIFAKEMAPKIL
EEHHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHCHHHH
VNSIAPGTISAYSGRDEEPEADLVGKIPLERLGDPMDIVMAIRFLMETEYITGQVINVDG
HHCCCCCCEEECCCCCCCCCCCCEECCCHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCC
GRMLF
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA