Click here to switch to the map view.

The map label for this gene is yxbB [H]

Identifier: 21674573

GI number: 21674573

Start: 1667982

End: 1668809

Strand: Reverse

Name: yxbB [H]

Synonym: CT1759

Alternate gene names: 21674573

Gene position: 1668809-1667982 (Counterclockwise)

Preceding gene: 21674574

Following gene: 21674572

Centisome position: 77.44

GC content: 58.57

Gene sequence:

>828_bases
TTGAAAGGGCAGAGCAAAAAACAGGAGGAGGCGGATGACTTTGGAAAAGTGAGTTTTCCAAAATTGCCTTGTCCCGAATG
CTTTCGGGACGGGGTTCAAGGCACAAAAAAATCATGGGCTTCAGCCCAAAATCTTGCTCGACAACCTTCGCGAGTCGTTG
TTGTTAGAGCAATAACAAAACGCTATAAAACAATGAGTTACACTATGAATGCGGCGGAGTTCAACGAGAAGATCATGAAG
GGCCATTTCCGCAAAATCTATCCGGTCATCGCCGCGCAGATCGTCGAGCGGACGGGCGTGCGTTCCGGGCGCTGCGTCGA
TCTCGGCGGCGGGCCGGGGATGCTCGGCGTCTGTCTGGCTAAAATCACCTCGCTGACTGTGACGGTGGTCGATCTCATGC
CGGAGTGCGTCGAGCTGGCCCGCGAGAACAGTGCCGAAGCGGGCGTCGCCGAGCGCGTTGATGTCGTGCAGGGGGTGGCC
GAAGCGTTGCCGTTCGATGACGCATCGATCGATCTGGTAGTGAGCCGGGGTTCGATCTTTTTCTGGGAGGATCAGCAAAA
AGGGCTTGCCGAGGTGTATCGCGTCCTGCGGCCCGGCGGCTGGGCGTGGATCGGCGGTGGCTTCGGCACGGCGGAGCTGC
TGCGCGAAATCGAGGCAGCCAAAGCCGACGATCCCGAGTGGAACCGCAAGCGCAGGGAGCGTATGACGCAGAATCCGCCC
GAGCACTTCAGAGCGATACTCGAACGGCTCGGCATCGATGGCGTCGTGGAGCATCAGGAGGCCGGAACCTGGATCATTTT
CCGCAAACCTGCGGAGGTGGAAGCATGA

Upstream 100 bases:

>100_bases
CTCCGGTGGTGGAGTAGGGGGGAGGGATTGGGCTAAAGCCCTTACTTACTATGCGTTATCTGCATACCCCGGACTGAAGT
CCGGGGCAATTGTCAAGAGT

Downstream 100 bases:

>100_bases
GAGCCGCATCGACTCGCACCCTCCTCTGGCTTCTGCCGTTCTTCCTGCTGTTGCTGGCAGCCTGCCAGCCGTCCGGCGGC
AAGAAGCCCGATGCGGCGAC

Product: UbiE/COQ5 family methlytransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKGQSKKQEEADDFGKVSFPKLPCPECFRDGVQGTKKSWASAQNLARQPSRVVVVRAITKRYKTMSYTMNAAEFNEKIMK
GHFRKIYPVIAAQIVERTGVRSGRCVDLGGGPGMLGVCLAKITSLTVTVVDLMPECVELARENSAEAGVAERVDVVQGVA
EALPFDDASIDLVVSRGSIFFWEDQQKGLAEVYRVLRPGGWAWIGGGFGTAELLREIEAAKADDPEWNRKRRERMTQNPP
EHFRAILERLGIDGVVEHQEAGTWIIFRKPAEVEA

Sequences:

>Translated_275_residues
MKGQSKKQEEADDFGKVSFPKLPCPECFRDGVQGTKKSWASAQNLARQPSRVVVVRAITKRYKTMSYTMNAAEFNEKIMK
GHFRKIYPVIAAQIVERTGVRSGRCVDLGGGPGMLGVCLAKITSLTVTVVDLMPECVELARENSAEAGVAERVDVVQGVA
EALPFDDASIDLVVSRGSIFFWEDQQKGLAEVYRVLRPGGWAWIGGGFGTAELLREIEAAKADDPEWNRKRRERMTQNPP
EHFRAILERLGIDGVVEHQEAGTWIIFRKPAEVEA
>Mature_275_residues
MKGQSKKQEEADDFGKVSFPKLPCPECFRDGVQGTKKSWASAQNLARQPSRVVVVRAITKRYKTMSYTMNAAEFNEKIMK
GHFRKIYPVIAAQIVERTGVRSGRCVDLGGGPGMLGVCLAKITSLTVTVVDLMPECVELARENSAEAGVAERVDVVQGVA
EALPFDDASIDLVVSRGSIFFWEDQQKGLAEVYRVLRPGGWAWIGGGFGTAELLREIEAAKADDPEWNRKRRERMTQNPP
EHFRAILERLGIDGVVEHQEAGTWIIFRKPAEVEA

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=109, Percent_Identity=35.7798165137615, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30522; Mature: 30522

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGQSKKQEEADDFGKVSFPKLPCPECFRDGVQGTKKSWASAQNLARQPSRVVVVRAITK
CCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
RYKTMSYTMNAAEFNEKIMKGHFRKIYPVIAAQIVERTGVRSGRCVDLGGGPGMLGVCLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
KITSLTVTVVDLMPECVELARENSAEAGVAERVDVVQGVAEALPFDDASIDLVVSRGSIF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEE
FWEDQQKGLAEVYRVLRPGGWAWIGGGFGTAELLREIEAAKADDPEWNRKRRERMTQNPP
EEECHHCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCH
EHFRAILERLGIDGVVEHQEAGTWIIFRKPAEVEA
HHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKGQSKKQEEADDFGKVSFPKLPCPECFRDGVQGTKKSWASAQNLARQPSRVVVVRAITK
CCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
RYKTMSYTMNAAEFNEKIMKGHFRKIYPVIAAQIVERTGVRSGRCVDLGGGPGMLGVCLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
KITSLTVTVVDLMPECVELARENSAEAGVAERVDVVQGVAEALPFDDASIDLVVSRGSIF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEE
FWEDQQKGLAEVYRVLRPGGWAWIGGGFGTAELLREIEAAKADDPEWNRKRRERMTQNPP
EEECHHCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCH
EHFRAILERLGIDGVVEHQEAGTWIIFRKPAEVEA
HHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]