Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 21674568

GI number: 21674568

Start: 1661887

End: 1664010

Strand: Reverse

Name: cirA [H]

Synonym: CT1754

Alternate gene names: 21674568

Gene position: 1664010-1661887 (Counterclockwise)

Preceding gene: 21674569

Following gene: 21674567

Centisome position: 77.22

GC content: 58.19

Gene sequence:

>2124_bases
ATGATTTGTCGTGAATGCCGATCAGACTCATTTTTTATCCATCGTTATAACTGTAAAAACATATCGTTCATGAATGTACT
GAATTCCCGATCCTGCCGGATACTTATGGTGGCGGCTATCATCGGTTCCGCAAGCTCGCAGGCTTGGGCCGCTGATACCG
TTCCAGGCTGGACGGCTGACGAAATTGTCATTACTGCTACCCGAACTGAAAACCCTGTCTCCAAACTGCCAATGGCCGTC
GAGGTGATCACCCGGCAGGAGATTGAAGAGAGCGGCTCCCTGAATCTTGCCGACGTGCTTGCGGAGGCGGAGGATGTCAA
TGCTCTCGAACCGGTGAACGGACGGCTTGGCGTGGCAAAATTACGCGGCCTTGGTAGCAGCCTGACGCTGGTGCTCATCG
ATGGCTACCGGTTGCAGTCCGGGTTTCAGGGCTACTCCGACCTGCGTGAAATTCCGGCCGGTATGATCGAGCGCATCGAA
ATCGTCAGGGGTTCCGGCTCGGCGCTCTACGGCAGCGATGCGGTGGGCGGCGTCATCAACATCATCACCCGCAAGCCGAC
GAAGGATTTGCATGGTGGCCTGTCAATTTCCGGGGGCGAGAGCCGCGCCGGAGAGGCGGGCACTGTCGAGACCGATGGTT
GGGTGAGCGGTTCGGCGGGCAAGCTCGGCTTCGCGGTGGCTGGGACCTATTACGATCGTGACCGTTACGACCGCGACCAG
TCCGACCTCATGACCGATGGCGACGACCGTCGCATCGCCTCCGGATCGGCCTCGCTGACCTGCGACCTGACGCCGGGTGT
GAAACTGACCGGCGGTATCGTCTATGCCGACAACTCGCTCGATGGCATCCGTACGCAAAACTCGGGTGATTTCGACCGCT
GGGTGGATAGCGACCGCCTGCTTGTGCATGCCGGAGCGGAAATAAAAACAGGCGAAGAGTCGAACCTTTCGTTGAAGGTT
GCCCGCAGCACCTACGACTGGCGGTCAGACATGGACAATCACGACGGCGTGCCGACCGTCACCAGCGCAACAGCATCCGG
CACCACGACGACCACTGAAACGACGATGGCCAGCCGCACGAAGGTGTCGCAGGATTACGACCAGTTCGATGCTCGCTGGA
CGGGGCGCATCGCCGAAGTCCATCGCCTGACTACCGGAGTTGAATATCGTACCGAGACGCGCACGGATTCGGGCAGCACC
GTCACGACAAAGGTGGTCACCAAAACCGGATTGGTCAACAGCGGGCCGACAACGATGGTGGCGACAGACAAGACGGATAT
TTCGCACGATGTCGATAATCTCGGCCTCTACCTCCAGGACGAGTTCACCGGCTTGAAGCCGCTGACGATCATCGCCGGTG
TGCGGTACGACGACCATTCCGATTTCGGTTCGGAGTACAGCCCCAAGGTTGCGGTGCTTTTGCCCGTCGATTCGCATCTC
AAACTGCGGGCTTCATACGGCGAGGGCTTTCGTGCGCCATCGATTTACGAACTCTACACCGGTTCGCTGACGACCAGAAG
AAGCATCGTCCTGTCGAATCCCGATCTCAAAGCTGAACGCTCGAAGACTTGGGAGGTTGGCGCTGACTTTTCACGGGGTG
GTTTCAACGCAGGTGTGACCGCTTTTCGCAACGAGGTCAGGAACATGATTTCGCTGGTGCTGGCCGATGACACCACCACG
CCCGACACCTACCAGTACCAGAACCTCTCGAAAGCGATGACGCGCGGCATCGAAATCAGCGCATCGCTCGCGCTGCCGCA
CGGCTTCACGCTCTCCGACCGGGTCAGCTTTCTCGATACGGAGAACCTCGATACCGGCGAAGCGCTGTTCTTCGCGCCCG
ATGTCGCCAATGTTCTCCGGCTCGATTACGCCAATAGCCGGTTCGGCCTGAAAGGCAACGTCAGAGTTGTCTCCACCGGC
ACGCAGTACAGCTCGGCGGATGAGAAGATTTCCGGCTACACGCTCGTGAACTGCTACCTCTCCAAATCGGTCTCGAAACA
CGCCGAGTTGTTCGCCGGAGTCGATAACCTCTTCAACGACGACGCCAATACCGGATATGGCAACAACGAAGGCGCGGGCG
CAATGGGTACCTATTTCTATGGTGGTTTGAATTTCAAACTGTAA

Upstream 100 bases:

>100_bases
TCGAAAAGCTCGAAGCCCTCGACAACCGCCTTCTCGCGCTTCGCACAAGGCTCCGCAGTGGCGAGCTGATCGAAGACGCG
GGGTAATCCCTCGTGTACCG

Downstream 100 bases:

>100_bases
TTGATGACGACAATGAAAAACATCCGGAAGGCATGTTCATCTCTTCTGATGCTGGTTGTGCTTTTCTCCTTCTGTGGCTT
GCAGGCAGAACCTGCGCAAT

Product: receptor, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MICRECRSDSFFIHRYNCKNISFMNVLNSRSCRILMVAAIIGSASSQAWAADTVPGWTADEIVITATRTENPVSKLPMAV
EVITRQEIEESGSLNLADVLAEAEDVNALEPVNGRLGVAKLRGLGSSLTLVLIDGYRLQSGFQGYSDLREIPAGMIERIE
IVRGSGSALYGSDAVGGVINIITRKPTKDLHGGLSISGGESRAGEAGTVETDGWVSGSAGKLGFAVAGTYYDRDRYDRDQ
SDLMTDGDDRRIASGSASLTCDLTPGVKLTGGIVYADNSLDGIRTQNSGDFDRWVDSDRLLVHAGAEIKTGEESNLSLKV
ARSTYDWRSDMDNHDGVPTVTSATASGTTTTTETTMASRTKVSQDYDQFDARWTGRIAEVHRLTTGVEYRTETRTDSGST
VTTKVVTKTGLVNSGPTTMVATDKTDISHDVDNLGLYLQDEFTGLKPLTIIAGVRYDDHSDFGSEYSPKVAVLLPVDSHL
KLRASYGEGFRAPSIYELYTGSLTTRRSIVLSNPDLKAERSKTWEVGADFSRGGFNAGVTAFRNEVRNMISLVLADDTTT
PDTYQYQNLSKAMTRGIEISASLALPHGFTLSDRVSFLDTENLDTGEALFFAPDVANVLRLDYANSRFGLKGNVRVVSTG
TQYSSADEKISGYTLVNCYLSKSVSKHAELFAGVDNLFNDDANTGYGNNEGAGAMGTYFYGGLNFKL

Sequences:

>Translated_707_residues
MICRECRSDSFFIHRYNCKNISFMNVLNSRSCRILMVAAIIGSASSQAWAADTVPGWTADEIVITATRTENPVSKLPMAV
EVITRQEIEESGSLNLADVLAEAEDVNALEPVNGRLGVAKLRGLGSSLTLVLIDGYRLQSGFQGYSDLREIPAGMIERIE
IVRGSGSALYGSDAVGGVINIITRKPTKDLHGGLSISGGESRAGEAGTVETDGWVSGSAGKLGFAVAGTYYDRDRYDRDQ
SDLMTDGDDRRIASGSASLTCDLTPGVKLTGGIVYADNSLDGIRTQNSGDFDRWVDSDRLLVHAGAEIKTGEESNLSLKV
ARSTYDWRSDMDNHDGVPTVTSATASGTTTTTETTMASRTKVSQDYDQFDARWTGRIAEVHRLTTGVEYRTETRTDSGST
VTTKVVTKTGLVNSGPTTMVATDKTDISHDVDNLGLYLQDEFTGLKPLTIIAGVRYDDHSDFGSEYSPKVAVLLPVDSHL
KLRASYGEGFRAPSIYELYTGSLTTRRSIVLSNPDLKAERSKTWEVGADFSRGGFNAGVTAFRNEVRNMISLVLADDTTT
PDTYQYQNLSKAMTRGIEISASLALPHGFTLSDRVSFLDTENLDTGEALFFAPDVANVLRLDYANSRFGLKGNVRVVSTG
TQYSSADEKISGYTLVNCYLSKSVSKHAELFAGVDNLFNDDANTGYGNNEGAGAMGTYFYGGLNFKL
>Mature_707_residues
MICRECRSDSFFIHRYNCKNISFMNVLNSRSCRILMVAAIIGSASSQAWAADTVPGWTADEIVITATRTENPVSKLPMAV
EVITRQEIEESGSLNLADVLAEAEDVNALEPVNGRLGVAKLRGLGSSLTLVLIDGYRLQSGFQGYSDLREIPAGMIERIE
IVRGSGSALYGSDAVGGVINIITRKPTKDLHGGLSISGGESRAGEAGTVETDGWVSGSAGKLGFAVAGTYYDRDRYDRDQ
SDLMTDGDDRRIASGSASLTCDLTPGVKLTGGIVYADNSLDGIRTQNSGDFDRWVDSDRLLVHAGAEIKTGEESNLSLKV
ARSTYDWRSDMDNHDGVPTVTSATASGTTTTTETTMASRTKVSQDYDQFDARWTGRIAEVHRLTTGVEYRTETRTDSGST
VTTKVVTKTGLVNSGPTTMVATDKTDISHDVDNLGLYLQDEFTGLKPLTIIAGVRYDDHSDFGSEYSPKVAVLLPVDSHL
KLRASYGEGFRAPSIYELYTGSLTTRRSIVLSNPDLKAERSKTWEVGADFSRGGFNAGVTAFRNEVRNMISLVLADDTTT
PDTYQYQNLSKAMTRGIEISASLALPHGFTLSDRVSFLDTENLDTGEALFFAPDVANVLRLDYANSRFGLKGNVRVVSTG
TQYSSADEKISGYTLVNCYLSKSVSKHAELFAGVDNLFNDDANTGYGNNEGAGAMGTYFYGGLNFKL

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=685, Percent_Identity=26.7153284671533, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1786798, Length=735, Percent_Identity=26.3945578231293, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1790405, Length=154, Percent_Identity=42.8571428571429, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76406; Mature: 76406

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICRECRSDSFFIHRYNCKNISFMNVLNSRSCRILMVAAIIGSASSQAWAADTVPGWTAD
CCCCCCCCCCEEEEEECCCCEEEHHHHCCCCCEEEEEEEHHCCCCCCCEECCCCCCCCCC
EIVITATRTENPVSKLPMAVEVITRQEIEESGSLNLADVLAEAEDVNALEPVNGRLGVAK
CEEEEEECCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
LRGLGSSLTLVLIDGYRLQSGFQGYSDLREIPAGMIERIEIVRGSGSALYGSDAVGGVIN
HHCCCCCEEEEEEECEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCCEE
IITRKPTKDLHGGLSISGGESRAGEAGTVETDGWVSGSAGKLGFAVAGTYYDRDRYDRDQ
EEECCCCHHHCCCEEECCCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEEECCHHCCCCH
SDLMTDGDDRRIASGSASLTCDLTPGVKLTGGIVYADNSLDGIRTQNSGDFDRWVDSDRL
HHCCCCCCCCEEECCCCEEEEECCCCCEEECCEEEECCCCCCCCCCCCCCHHHHCCCCCE
LVHAGAEIKTGEESNLSLKVARSTYDWRSDMDNHDGVPTVTSATASGTTTTTETTMASRT
EEEECCEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHH
KVSQDYDQFDARWTGRIAEVHRLTTGVEYRTETRTDSGSTVTTKVVTKTGLVNSGPTTMV
HHHCCHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCCEEE
ATDKTDISHDVDNLGLYLQDEFTGLKPLTIIAGVRYDDHSDFGSEYSPKVAVLLPVDSHL
EECCCCCCCCHHHCCEEEEECCCCCCCEEEEEECEECCCCCCCCCCCCEEEEEEECCCCE
KLRASYGEGFRAPSIYELYTGSLTTRRSIVLSNPDLKAERSKTWEVGADFSRGGFNAGVT
EEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCHH
AFRNEVRNMISLVLADDTTTPDTYQYQNLSKAMTRGIEISASLALPHGFTLSDRVSFLDT
HHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCHHCCEEEEEC
ENLDTGEALFFAPDVANVLRLDYANSRFGLKGNVRVVSTGTQYSSADEKISGYTLVNCYL
CCCCCCCEEEECCCHHHHHEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEH
SKSVSKHAELFAGVDNLFNDDANTGYGNNEGAGAMGTYFYGGLNFKL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECEEECC
>Mature Secondary Structure
MICRECRSDSFFIHRYNCKNISFMNVLNSRSCRILMVAAIIGSASSQAWAADTVPGWTAD
CCCCCCCCCCEEEEEECCCCEEEHHHHCCCCCEEEEEEEHHCCCCCCCEECCCCCCCCCC
EIVITATRTENPVSKLPMAVEVITRQEIEESGSLNLADVLAEAEDVNALEPVNGRLGVAK
CEEEEEECCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
LRGLGSSLTLVLIDGYRLQSGFQGYSDLREIPAGMIERIEIVRGSGSALYGSDAVGGVIN
HHCCCCCEEEEEEECEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCCEE
IITRKPTKDLHGGLSISGGESRAGEAGTVETDGWVSGSAGKLGFAVAGTYYDRDRYDRDQ
EEECCCCHHHCCCEEECCCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEEECCHHCCCCH
SDLMTDGDDRRIASGSASLTCDLTPGVKLTGGIVYADNSLDGIRTQNSGDFDRWVDSDRL
HHCCCCCCCCEEECCCCEEEEECCCCCEEECCEEEECCCCCCCCCCCCCCHHHHCCCCCE
LVHAGAEIKTGEESNLSLKVARSTYDWRSDMDNHDGVPTVTSATASGTTTTTETTMASRT
EEEECCEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHH
KVSQDYDQFDARWTGRIAEVHRLTTGVEYRTETRTDSGSTVTTKVVTKTGLVNSGPTTMV
HHHCCHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCCEEE
ATDKTDISHDVDNLGLYLQDEFTGLKPLTIIAGVRYDDHSDFGSEYSPKVAVLLPVDSHL
EECCCCCCCCHHHCCEEEEECCCCCCCEEEEEECEECCCCCCCCCCCCEEEEEEECCCCE
KLRASYGEGFRAPSIYELYTGSLTTRRSIVLSNPDLKAERSKTWEVGADFSRGGFNAGVT
EEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCHH
AFRNEVRNMISLVLADDTTTPDTYQYQNLSKAMTRGIEISASLALPHGFTLSDRVSFLDT
HHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCHHCCEEEEEC
ENLDTGEALFFAPDVANVLRLDYANSRFGLKGNVRVVSTGTQYSSADEKISGYTLVNCYL
CCCCCCCEEEECCCHHHHHEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEH
SKSVSKHAELFAGVDNLFNDDANTGYGNNEGAGAMGTYFYGGLNFKL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]