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The map label for this gene is ywlC [H]

Identifier: 21674532

GI number: 21674532

Start: 1627216

End: 1628187

Strand: Direct

Name: ywlC [H]

Synonym: CT1715

Alternate gene names: 21674532

Gene position: 1627216-1628187 (Clockwise)

Preceding gene: 21674531

Following gene: 21674545

Centisome position: 75.51

GC content: 60.29

Gene sequence:

>972_bases
ATGCAGACCCTCGTGACTGACCGGCCTGAAGAGGCCGCAAGCTGGCTCAATCGTAGCGAAACGGTCGCATTTCCGACCGA
AACTGTTTACGGTCTCGGAGCCGACGCCTTTAATCCGGACGCTGTGGCGAAAATTTTCAAGGCGAAAGGACGGCCTTCGG
ACAACCCACTGATCGTGCACGTAGCGACGCCGGAGCAAATTGGCGAGGTGGCGGCGGAGATCGGTGAGACGGCAAAGATA
CTCGTCGAGCGCTTTTTCCCCGGCCCGCTGACGCTGGTGCTAAAAAAGCGCGCCGCCGTGCCGGAGATTGTCTCCGCCGG
TCTGCCGACCATCGGCGTGCGCTGCCCGTCGCACCCAATCGCCTCGGAGTTTCTGCGCCACTGCAAACACCCGGTCGCCG
CGCCGTCAGCCAACGTTTCAGGACGCCCAAGCCCGACCGACTGGAAAACCGTCTACCACGACCTCGGCGGCAAAATCGCC
TGCCTTTTGCGCGGCGAACCAAGCACCATCGGCCTTGAATCGACCATCGTTGACTGCTCGGTCAACCCGCCGCGCCTGTT
GCGCACCGGAGCCGTCAGCATCGAATTGCTCCGCGAGTTGGTGCCCGACATCGAAATAGCGACCGCCTGCAAGCCGGGCG
AAGCCCCGAAAAGCCCCGGCCAGAAATACCGCCACTACAGCCCCGAAGCCGAAATCATCCTCGTCGAATCTCCACCATCA
AACCTGCAGACAGACTTGCACGCTGCATGGATCGGCCTTGCCGCTCCGCCCGCCGGAGCCGCAAAATCTCTCCAATGCCG
CGACATGGACGAATACGCCCGCGTGCTGTTCGGATTTTTCAGGACGTGCGATGCAGAAGGGATTCGAACAATTTATTGCG
AACTGCCGCCGGAAAAGGGGATCGGACGGGCGATACGGGATCGATTGGTTAAGGCTGCGGGAGAGGAAGTAAAAAATTCA
GATAAGCAATAA

Upstream 100 bases:

>100_bases
CAGCGTGCCGCTGGCCGGAGCCATCGCGGGCCTCTGCTGCTACACCTGGTTTTTCCCCGAAGCGCTGAAGGCGCTCGCAC
ACTGACCGCACCCCTCATCG

Downstream 100 bases:

>100_bases
ACATCTGTCAAAGGGTCTGTAAGATACCGTGTGTAAACGGTTATAGTTTCCTCTCATGTAACAAGGAGGAAAACCATGTC
TTTTTGTCCTCTGTTCCGCT

Product: SUA5/YciO/YrdC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQTLVTDRPEEAASWLNRSETVAFPTETVYGLGADAFNPDAVAKIFKAKGRPSDNPLIVHVATPEQIGEVAAEIGETAKI
LVERFFPGPLTLVLKKRAAVPEIVSAGLPTIGVRCPSHPIASEFLRHCKHPVAAPSANVSGRPSPTDWKTVYHDLGGKIA
CLLRGEPSTIGLESTIVDCSVNPPRLLRTGAVSIELLRELVPDIEIATACKPGEAPKSPGQKYRHYSPEAEIILVESPPS
NLQTDLHAAWIGLAAPPAGAAKSLQCRDMDEYARVLFGFFRTCDAEGIRTIYCELPPEKGIGRAIRDRLVKAAGEEVKNS
DKQ

Sequences:

>Translated_323_residues
MQTLVTDRPEEAASWLNRSETVAFPTETVYGLGADAFNPDAVAKIFKAKGRPSDNPLIVHVATPEQIGEVAAEIGETAKI
LVERFFPGPLTLVLKKRAAVPEIVSAGLPTIGVRCPSHPIASEFLRHCKHPVAAPSANVSGRPSPTDWKTVYHDLGGKIA
CLLRGEPSTIGLESTIVDCSVNPPRLLRTGAVSIELLRELVPDIEIATACKPGEAPKSPGQKYRHYSPEAEIILVESPPS
NLQTDLHAAWIGLAAPPAGAAKSLQCRDMDEYARVLFGFFRTCDAEGIRTIYCELPPEKGIGRAIRDRLVKAAGEEVKNS
DKQ
>Mature_323_residues
MQTLVTDRPEEAASWLNRSETVAFPTETVYGLGADAFNPDAVAKIFKAKGRPSDNPLIVHVATPEQIGEVAAEIGETAKI
LVERFFPGPLTLVLKKRAAVPEIVSAGLPTIGVRCPSHPIASEFLRHCKHPVAAPSANVSGRPSPTDWKTVYHDLGGKIA
CLLRGEPSTIGLESTIVDCSVNPPRLLRTGAVSIELLRELVPDIEIATACKPGEAPKSPGQKYRHYSPEAEIILVESPPS
NLQTDLHAAWIGLAAPPAGAAKSLQCRDMDEYARVLFGFFRTCDAEGIRTIYCELPPEKGIGRAIRDRLVKAAGEEVKNS
DKQ

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=133, Percent_Identity=32.3308270676692, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=206, Percent_Identity=29.6116504854369, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=362, Percent_Identity=33.9779005524862, Blast_Score=182, Evalue=7e-47,
Organism=Drosophila melanogaster, GI78707274, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34808; Mature: 34808

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLVTDRPEEAASWLNRSETVAFPTETVYGLGADAFNPDAVAKIFKAKGRPSDNPLIVH
CCCCCCCCCHHHHHHHCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
VATPEQIGEVAAEIGETAKILVERFFPGPLTLVLKKRAAVPEIVSAGLPTIGVRCPSHPI
EECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCEEECCCCCCHH
ASEFLRHCKHPVAAPSANVSGRPSPTDWKTVYHDLGGKIACLLRGEPSTIGLESTIVDCS
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECC
VNPPRLLRTGAVSIELLRELVPDIEIATACKPGEAPKSPGQKYRHYSPEAEIILVESPPS
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEECCCC
NLQTDLHAAWIGLAAPPAGAAKSLQCRDMDEYARVLFGFFRTCDAEGIRTIYCELPPEKG
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
IGRAIRDRLVKAAGEEVKNSDKQ
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQTLVTDRPEEAASWLNRSETVAFPTETVYGLGADAFNPDAVAKIFKAKGRPSDNPLIVH
CCCCCCCCCHHHHHHHCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
VATPEQIGEVAAEIGETAKILVERFFPGPLTLVLKKRAAVPEIVSAGLPTIGVRCPSHPI
EECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCEEECCCCCCHH
ASEFLRHCKHPVAAPSANVSGRPSPTDWKTVYHDLGGKIACLLRGEPSTIGLESTIVDCS
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECC
VNPPRLLRTGAVSIELLRELVPDIEIATACKPGEAPKSPGQKYRHYSPEAEIILVESPPS
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEECCCC
NLQTDLHAAWIGLAAPPAGAAKSLQCRDMDEYARVLFGFFRTCDAEGIRTIYCELPPEKG
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
IGRAIRDRLVKAAGEEVKNSDKQ
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]