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The map label for this gene is comM [H]

Identifier: 21674459

GI number: 21674459

Start: 1552152

End: 1553708

Strand: Direct

Name: comM [H]

Synonym: CT1641

Alternate gene names: 21674459

Gene position: 1552152-1553708 (Clockwise)

Preceding gene: 21674458

Following gene: 21674461

Centisome position: 72.03

GC content: 61.59

Gene sequence:

>1557_bases
ATGCTTACCAAACTCTGCGCGGCGGCGCTGCTAGGTATCGACGCCCTGAAGGTCGAGATTGAAACGAATGTCTCTGGTGG
TTTGCCGGCCTTCACGGTGGTCGGGCTGCCGGACAGCGCAATCAAGGAGAGCCGCGAGCGCATTCTGACCGCTATCCGCA
ACTCCGGCTTTGAGCTGCCGTCGAAAAAAATCACCGTCAACCTCGCACCTGCCGATGTCAAAAAAGAGGGCACGGCGTTC
GATCTTGGCATCGCGGTCGGCCTGCTCGGCTCACTCGGTGAGATCAAGGGGCAGTTCGAGGATACCATCGTGCTGGGCGA
GCTAGCGCTCGACGGATCAGTGCGGCGCATCAGCGGCACGTTGCCGATGGCCATAATGGCTGCGCGGGAAAACATCCGAT
GGATGATCGTGCCAAAGATGAACGCGGCGGAAGCTGCTGTAGCGATTTCGGCAATGGGCGCGGCAACGAAGGTGTTCGGC
GTCGAAACGCTGGTCGAGGCTGCGGGGCTGCTCAGCGGCAACATCACGCCCGAACCGGTCAGTGTGAATGTCGCTGAACT
GTTCGACTGCGAGCCGGATTACCCGGTCGATTTTGCCGAAATCAAGGGGCAGCTCGCCGCCAAAAAAGCGATCGAAATTT
CCGCGGCAGGCGGACATAATCTGCTCATGATCGGCCCGCCCGGAAGCGGTAAAACACTGCTCGCCAAAGCGATTCCGGGC
ATTCTTCCGCCGCTCGGCTTTGAGGAGTCGCTTGAAACCACCAAAATCTACTCGGTATCGAGCCTGCTCGAACGCAACCG
CCCGCTCATGATCACGCGCCCCTTCCGCAGTCCGCACCACACCACGAGCAACGTAGCGCTAATCGGCGGCGGTGCGCAGG
CCAAGCCTGGCGAGGTGAGCCTGGCGCACAACGGCGTACTCTTCCTGGACGAGTTGCCGGAGTTCACCCGCAACGCGCTC
GAAGTGCTGCGCCAGCCGCTCGAAGACCGCGAAGTAACCGTGGCCCGCGCGGCGCTCTCGACGCGCTACCCGGCGGGCTT
CATGCTGGTGGCTGCAATGAACCCGAGTCCCGCCGGGCCGCTCAAGGATCGCGATGGCCTGCCGACCGCATCGCCGGAGC
AGATCCGGCGCTACCTTTCCAAAATATCCGGCCCGCTGCTCGACCGCATCGACATCCACATCGACGTCCCAAAGGTGGAG
AACATCGAGCTGTTCTCGAACAGTTCGGCGGAAAGTTCCGGCGAGATTCGCAAGCGGGTGATCGCGGCACGCGCCATCCA
GCACGAGCGCTTCGCCTCGCTCCCCTCACCGCGCATCTTCACCAACGCGCAGATGAATTCGAAGCTGATCCGCAAGTTCT
GCAAGCTTGACAAGGAGAGCGCCGAAAAGCTGATGGAGGCGATGAACCGCCTCAACCTCTCGGCCAGGGCGCACGACCGC
ATCCTCAAGGTAAGCCGCACCATCGCCGACCTCGAAGGCGCGGAACATATCGAAATGAAGCATTTGGTGCAGGGCATCCA
GTACCGCAGCCTCGACCGCGAGTTCTGGAGCTTTTGA

Upstream 100 bases:

>100_bases
ATCACCGCATTTTTCCGTATAATCAGGCAAATGCGCTGGTTATCCCCCGACCCTTTTAGAACCGGCGCTGGCAGTGATCA
ACCCCTACTCATTGTCTCAT

Downstream 100 bases:

>100_bases
GAGAAAAGAGGACAGACTGGACGGATCAGGGGAAATGCGCCGCATGTCAGATGTTCAGAGAAAAAGAGCCTGCTTGGCTA
TATTAAGGACTTTATTGTCG

Product: magnesium-chelatase subunit D/I family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLTKLCAAALLGIDALKVEIETNVSGGLPAFTVVGLPDSAIKESRERILTAIRNSGFELPSKKITVNLAPADVKKEGTAF
DLGIAVGLLGSLGEIKGQFEDTIVLGELALDGSVRRISGTLPMAIMAARENIRWMIVPKMNAAEAAVAISAMGAATKVFG
VETLVEAAGLLSGNITPEPVSVNVAELFDCEPDYPVDFAEIKGQLAAKKAIEISAAGGHNLLMIGPPGSGKTLLAKAIPG
ILPPLGFEESLETTKIYSVSSLLERNRPLMITRPFRSPHHTTSNVALIGGGAQAKPGEVSLAHNGVLFLDELPEFTRNAL
EVLRQPLEDREVTVARAALSTRYPAGFMLVAAMNPSPAGPLKDRDGLPTASPEQIRRYLSKISGPLLDRIDIHIDVPKVE
NIELFSNSSAESSGEIRKRVIAARAIQHERFASLPSPRIFTNAQMNSKLIRKFCKLDKESAEKLMEAMNRLNLSARAHDR
ILKVSRTIADLEGAEHIEMKHLVQGIQYRSLDREFWSF

Sequences:

>Translated_518_residues
MLTKLCAAALLGIDALKVEIETNVSGGLPAFTVVGLPDSAIKESRERILTAIRNSGFELPSKKITVNLAPADVKKEGTAF
DLGIAVGLLGSLGEIKGQFEDTIVLGELALDGSVRRISGTLPMAIMAARENIRWMIVPKMNAAEAAVAISAMGAATKVFG
VETLVEAAGLLSGNITPEPVSVNVAELFDCEPDYPVDFAEIKGQLAAKKAIEISAAGGHNLLMIGPPGSGKTLLAKAIPG
ILPPLGFEESLETTKIYSVSSLLERNRPLMITRPFRSPHHTTSNVALIGGGAQAKPGEVSLAHNGVLFLDELPEFTRNAL
EVLRQPLEDREVTVARAALSTRYPAGFMLVAAMNPSPAGPLKDRDGLPTASPEQIRRYLSKISGPLLDRIDIHIDVPKVE
NIELFSNSSAESSGEIRKRVIAARAIQHERFASLPSPRIFTNAQMNSKLIRKFCKLDKESAEKLMEAMNRLNLSARAHDR
ILKVSRTIADLEGAEHIEMKHLVQGIQYRSLDREFWSF
>Mature_518_residues
MLTKLCAAALLGIDALKVEIETNVSGGLPAFTVVGLPDSAIKESRERILTAIRNSGFELPSKKITVNLAPADVKKEGTAF
DLGIAVGLLGSLGEIKGQFEDTIVLGELALDGSVRRISGTLPMAIMAARENIRWMIVPKMNAAEAAVAISAMGAATKVFG
VETLVEAAGLLSGNITPEPVSVNVAELFDCEPDYPVDFAEIKGQLAAKKAIEISAAGGHNLLMIGPPGSGKTLLAKAIPG
ILPPLGFEESLETTKIYSVSSLLERNRPLMITRPFRSPHHTTSNVALIGGGAQAKPGEVSLAHNGVLFLDELPEFTRNAL
EVLRQPLEDREVTVARAALSTRYPAGFMLVAAMNPSPAGPLKDRDGLPTASPEQIRRYLSKISGPLLDRIDIHIDVPKVE
NIELFSNSSAESSGEIRKRVIAARAIQHERFASLPSPRIFTNAQMNSKLIRKFCKLDKESAEKLMEAMNRLNLSARAHDR
ILKVSRTIADLEGAEHIEMKHLVQGIQYRSLDREFWSF

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=510, Percent_Identity=42.7450980392157, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55909; Mature: 55909

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKLCAAALLGIDALKVEIETNVSGGLPAFTVVGLPDSAIKESRERILTAIRNSGFELP
CHHHHHHHHHHCCEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
SKKITVNLAPADVKKEGTAFDLGIAVGLLGSLGEIKGQFEDTIVLGELALDGSVRRISGT
CCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCC
LPMAIMAARENIRWMIVPKMNAAEAAVAISAMGAATKVFGVETLVEAAGLLSGNITPEPV
CCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCC
SVNVAELFDCEPDYPVDFAEIKGQLAAKKAIEISAAGGHNLLMIGPPGSGKTLLAKAIPG
EEEHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCHHHHHCCC
ILPPLGFEESLETTKIYSVSSLLERNRPLMITRPFRSPHHTTSNVALIGGGAQAKPGEVS
CCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEE
LAHNGVLFLDELPEFTRNALEVLRQPLEDREVTVARAALSTRYPAGFMLVAAMNPSPAGP
EECCCEEEEHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
LKDRDGLPTASPEQIRRYLSKISGPLLDRIDIHIDVPKVENIELFSNSSAESSGEIRKRV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEECCCCCCCHHHHHHHH
IAARAIQHERFASLPSPRIFTNAQMNSKLIRKFCKLDKESAEKLMEAMNRLNLSARAHDR
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
ILKVSRTIADLEGAEHIEMKHLVQGIQYRSLDREFWSF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTKLCAAALLGIDALKVEIETNVSGGLPAFTVVGLPDSAIKESRERILTAIRNSGFELP
CHHHHHHHHHHCCEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
SKKITVNLAPADVKKEGTAFDLGIAVGLLGSLGEIKGQFEDTIVLGELALDGSVRRISGT
CCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCC
LPMAIMAARENIRWMIVPKMNAAEAAVAISAMGAATKVFGVETLVEAAGLLSGNITPEPV
CCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCC
SVNVAELFDCEPDYPVDFAEIKGQLAAKKAIEISAAGGHNLLMIGPPGSGKTLLAKAIPG
EEEHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCHHHHHCCC
ILPPLGFEESLETTKIYSVSSLLERNRPLMITRPFRSPHHTTSNVALIGGGAQAKPGEVS
CCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEE
LAHNGVLFLDELPEFTRNALEVLRQPLEDREVTVARAALSTRYPAGFMLVAAMNPSPAGP
EECCCEEEEHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
LKDRDGLPTASPEQIRRYLSKISGPLLDRIDIHIDVPKVENIELFSNSSAESSGEIRKRV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEECCCCCCCHHHHHHHH
IAARAIQHERFASLPSPRIFTNAQMNSKLIRKFCKLDKESAEKLMEAMNRLNLSARAHDR
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
ILKVSRTIADLEGAEHIEMKHLVQGIQYRSLDREFWSF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]