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The map label for this gene is lolC [H]

Identifier: 21674420

GI number: 21674420

Start: 1509290

End: 1510561

Strand: Reverse

Name: lolC [H]

Synonym: CT1602

Alternate gene names: 21674420

Gene position: 1510561-1509290 (Counterclockwise)

Preceding gene: 21674425

Following gene: 21674417

Centisome position: 70.1

GC content: 57.63

Gene sequence:

>1272_bases
ATGACCTTCCTTGACCATTTTCGCTTTGCCTGGGTGCACCTGCGGGAGAGAAAGCGCCAGACCTCGCTGACGGTGCTTGG
TGTGGCGGTCGGTTCGGCGATGATGATCACCACCATCGCTGTGGCGCGGGGGTCGTCGCTGAATGTTTTTCTGAAGCTCA
TCGATGTTGCCCCGCACATTACCATCGGCGCAGACAGGGTGGTGCCGGAGGTGCCCGACAACCTCGTCGGAATGATGCAG
GGGAGGATCGCCTTTGTCCGCAAGAACGTGACGACCGACCGCAAGGTGGTGATCAAGAACTACAGTCAGGTGATTGCGAC
CGTCAGTCCGATGAGGGAGGTGGTCGATATTTCACCCTATGTTACCAGCAAGCTGCTTGCCCGCAACAAAAACCGCTTCA
CTTCCTGCTTCGCCAAAGGGGTGGTGCCGTCGCTCGAAGGTGAAATCGCCGGGCTGAAAAAGAATTTGCTCGACCCCGAG
GCGCTCACCGAGCTGGGCTGGACGCCGAACGGTATCATCCTTGGCTCGATGCTGGCCGAGAAGCTGAAAGTGAAATACCG
CGATACGATCATGCTGGTGGACAAGGAGGGACATGAATATCCGGTGATGGTCGTGGGGCGGTTCAGGAGCGGCTTTAACA
CCAAGGACGACAAAGAGGCCTACGTCAATCTGGCGCTGGCGCAGCGGATGGAGTCGCTGGCATCGAATACCGTGACTGGC
ATCGGCCTGCGGATTGCGAACATCGGCCAGGCAGACGCGCTTGCGGCGAGGATTCAGAAACTTACCGGCTACGAAACCAA
AAGCTGGAGCGAAAGCAACAAGAATGTGATCGATTTCTACAATCGTAACGGTACAATCACGCTGGTACTGGTGAGTTTCG
TGTTCGTGGTGGCGGGACTTGGCGTGTCGTCGGTGATGACAACGGTGGTGCTCCAGAAGGTGAAAGATATCGCCATTCTG
CGCTCCATGGGCGTTCAGCGGGGAAGCATTACGCGCATTTTTATGCTCGAAGGGCTGATCATTGGCGCCACAGGTTCGCT
GGTTGGCAGTCCGGTGGGGCATCTGATTTGCGACCTTATCAGCAGGATACGCTTCGCTCCGAGCAGCGCGGGCGTTATCA
GCAGTGATCGGCTTCTTGTTGCTGAAACACCTGACGCACATCTCATCGTGATCGGTTTTGGCATTCTGATTGCCGTGATC
TCTTCGGTGGGGCCAGCCCGCCGAGCCACGAGTTACCTGCCGGTGCGCGTCCTGCGCGGGGAGGTGGGGTAA

Upstream 100 bases:

>100_bases
GCATGGTGTACGGTATGAAATCAAGATAGAGTATTTGGCTGATATTTCATTGTTGCATGATGAAATACGGTGCATTGAAA
TCCCCTGAATCCGTCAGAAT

Downstream 100 bases:

>100_bases
ACTGCATGTTTTCCTCTGTTGTGCGTCCCGCTTGCCGTGCTTCGTCAGCCTTGTCATCAAGCCATTCACGACGCGGAAAA
CATGCGTTCATTCAGGCATT

Product: lipoprotein releasing system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTFLDHFRFAWVHLRERKRQTSLTVLGVAVGSAMMITTIAVARGSSLNVFLKLIDVAPHITIGADRVVPEVPDNLVGMMQ
GRIAFVRKNVTTDRKVVIKNYSQVIATVSPMREVVDISPYVTSKLLARNKNRFTSCFAKGVVPSLEGEIAGLKKNLLDPE
ALTELGWTPNGIILGSMLAEKLKVKYRDTIMLVDKEGHEYPVMVVGRFRSGFNTKDDKEAYVNLALAQRMESLASNTVTG
IGLRIANIGQADALAARIQKLTGYETKSWSESNKNVIDFYNRNGTITLVLVSFVFVVAGLGVSSVMTTVVLQKVKDIAIL
RSMGVQRGSITRIFMLEGLIIGATGSLVGSPVGHLICDLISRIRFAPSSAGVISSDRLLVAETPDAHLIVIGFGILIAVI
SSVGPARRATSYLPVRVLRGEVG

Sequences:

>Translated_423_residues
MTFLDHFRFAWVHLRERKRQTSLTVLGVAVGSAMMITTIAVARGSSLNVFLKLIDVAPHITIGADRVVPEVPDNLVGMMQ
GRIAFVRKNVTTDRKVVIKNYSQVIATVSPMREVVDISPYVTSKLLARNKNRFTSCFAKGVVPSLEGEIAGLKKNLLDPE
ALTELGWTPNGIILGSMLAEKLKVKYRDTIMLVDKEGHEYPVMVVGRFRSGFNTKDDKEAYVNLALAQRMESLASNTVTG
IGLRIANIGQADALAARIQKLTGYETKSWSESNKNVIDFYNRNGTITLVLVSFVFVVAGLGVSSVMTTVVLQKVKDIAIL
RSMGVQRGSITRIFMLEGLIIGATGSLVGSPVGHLICDLISRIRFAPSSAGVISSDRLLVAETPDAHLIVIGFGILIAVI
SSVGPARRATSYLPVRVLRGEVG
>Mature_422_residues
TFLDHFRFAWVHLRERKRQTSLTVLGVAVGSAMMITTIAVARGSSLNVFLKLIDVAPHITIGADRVVPEVPDNLVGMMQG
RIAFVRKNVTTDRKVVIKNYSQVIATVSPMREVVDISPYVTSKLLARNKNRFTSCFAKGVVPSLEGEIAGLKKNLLDPEA
LTELGWTPNGIILGSMLAEKLKVKYRDTIMLVDKEGHEYPVMVVGRFRSGFNTKDDKEAYVNLALAQRMESLASNTVTGI
GLRIANIGQADALAARIQKLTGYETKSWSESNKNVIDFYNRNGTITLVLVSFVFVVAGLGVSSVMTTVVLQKVKDIAILR
SMGVQRGSITRIFMLEGLIIGATGSLVGSPVGHLICDLISRIRFAPSSAGVISSDRLLVAETPDAHLIVIGFGILIAVIS
SVGPARRATSYLPVRVLRGEVG

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=417, Percent_Identity=24.220623501199, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45923; Mature: 45791

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLDHFRFAWVHLRERKRQTSLTVLGVAVGSAMMITTIAVARGSSLNVFLKLIDVAPHI
CCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
TIGADRVVPEVPDNLVGMMQGRIAFVRKNVTTDRKVVIKNYSQVIATVSPMREVVDISPY
EECCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
VTSKLLARNKNRFTSCFAKGVVPSLEGEIAGLKKNLLDPEALTELGWTPNGIILGSMLAE
HHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCEEHHHHHHH
KLKVKYRDTIMLVDKEGHEYPVMVVGRFRSGFNTKDDKEAYVNLALAQRMESLASNTVTG
HHHEEECCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEE
IGLRIANIGQADALAARIQKLTGYETKSWSESNKNVIDFYNRNGTITLVLVSFVFVVAGL
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCC
GVSSVMTTVVLQKVKDIAILRSMGVQRGSITRIFMLEGLIIGATGSLVGSPVGHLICDLI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCHHCCHHHHHHHHHH
SRIRFAPSSAGVISSDRLLVAETPDAHLIVIGFGILIAVISSVGPARRATSYLPVRVLRG
HHHCCCCCCCCEECCCCEEEEECCCCEEEEHHHHHHHHHHHCCCCHHHHCCCCCHHHHCC
EVG
CCC
>Mature Secondary Structure 
TFLDHFRFAWVHLRERKRQTSLTVLGVAVGSAMMITTIAVARGSSLNVFLKLIDVAPHI
CCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
TIGADRVVPEVPDNLVGMMQGRIAFVRKNVTTDRKVVIKNYSQVIATVSPMREVVDISPY
EECCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
VTSKLLARNKNRFTSCFAKGVVPSLEGEIAGLKKNLLDPEALTELGWTPNGIILGSMLAE
HHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCEEHHHHHHH
KLKVKYRDTIMLVDKEGHEYPVMVVGRFRSGFNTKDDKEAYVNLALAQRMESLASNTVTG
HHHEEECCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEE
IGLRIANIGQADALAARIQKLTGYETKSWSESNKNVIDFYNRNGTITLVLVSFVFVVAGL
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCC
GVSSVMTTVVLQKVKDIAILRSMGVQRGSITRIFMLEGLIIGATGSLVGSPVGHLICDLI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCHHCCHHHHHHHHHH
SRIRFAPSSAGVISSDRLLVAETPDAHLIVIGFGILIAVISSVGPARRATSYLPVRVLRG
HHHCCCCCCCCEECCCCEEEEECCCCEEEEHHHHHHHHHHHCCCCHHHHCCCCCHHHHCC
EVG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]