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The map label for this gene is pabA [H]

Identifier: 21674383

GI number: 21674383

Start: 1474949

End: 1475512

Strand: Reverse

Name: pabA [H]

Synonym: CT1565

Alternate gene names: 21674383

Gene position: 1475512-1474949 (Counterclockwise)

Preceding gene: 21674384

Following gene: 21674382

Centisome position: 68.47

GC content: 59.4

Gene sequence:

>564_bases
ATGATTCTTGTTATAGACAATTACGACTCGTTTACGTACAACCTTGTCCAGTACATCGGCGAACTTGGGGCTGAGGTCGC
GGTGTACCGGAACGACGAACTGACCGTCGAGCAGGCGCTGGCGCTTGAGCCGGAGAAGATCGTCATCTCTCCGGGGCCGG
GTACGCCTGCGGATGCCGGAATCTCCATTCCGCTCATCAACGTCGTCAAGGGCAACATTCCGCTCTTCGGCGTCTGCCTC
GGCCATCAGGCCATCGGCGAAGCGCTCGGCGGCAAGGTCGTTCGCGCCGGGCAGATCATGCACGGCAAGACCTCGCAGAT
TTATCACGACGGCAAAGGGGTGTTCCGCGGCCTTCCCAATCCCTTTACGGCGACCCGCTACCACTCGCTCGTCGTGGAGC
GCGAAAGCCTGCCAGCAGAGCTTGAAATCACGGCATGGACTGAAGACGGCGTCATCATGGGTCTCCAGTCCAGCGAACTT
GGCCTGTACGGCGTGCAGTTCCATCCCGAATCGATCATGACCTCGGTCGGCCACGACCTCATCAGGAACTTCCTTGAACT
CTGA

Upstream 100 bases:

>100_bases
TATGCCTTGAAGTCTGCCAGCGGAGCCGACGAATATCGATGCAGCGGGTTTTGGGAAAAATTCTTTTAAGTCTTTGAAAA
TTAGTGTTTTACGCGCTTTC

Downstream 100 bases:

>100_bases
GCGCAGCATGGCAGACCAGGAGTGCAAAAAACCGGGCTGGGCCGTTCCGCCGCCGAAGCCCTTCTCTTCCGAAGAGATTT
CGCTCCTGCCGGGCAGCGAG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILVIDNYDSFTYNLVQYIGELGAEVAVYRNDELTVEQALALEPEKIVISPGPGTPADAGISIPLINVVKGNIPLFGVCL
GHQAIGEALGGKVVRAGQIMHGKTSQIYHDGKGVFRGLPNPFTATRYHSLVVERESLPAELEITAWTEDGVIMGLQSSEL
GLYGVQFHPESIMTSVGHDLIRNFLEL

Sequences:

>Translated_187_residues
MILVIDNYDSFTYNLVQYIGELGAEVAVYRNDELTVEQALALEPEKIVISPGPGTPADAGISIPLINVVKGNIPLFGVCL
GHQAIGEALGGKVVRAGQIMHGKTSQIYHDGKGVFRGLPNPFTATRYHSLVVERESLPAELEITAWTEDGVIMGLQSSEL
GLYGVQFHPESIMTSVGHDLIRNFLEL
>Mature_187_residues
MILVIDNYDSFTYNLVQYIGELGAEVAVYRNDELTVEQALALEPEKIVISPGPGTPADAGISIPLINVVKGNIPLFGVCL
GHQAIGEALGGKVVRAGQIMHGKTSQIYHDGKGVFRGLPNPFTATRYHSLVVERESLPAELEITAWTEDGVIMGLQSSEL
GLYGVQFHPESIMTSVGHDLIRNFLEL

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=175, Percent_Identity=30.8571428571429, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=62.3655913978495, Blast_Score=244, Evalue=2e-66,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.8502673796791, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786215, Length=161, Percent_Identity=31.6770186335404, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788854, Length=191, Percent_Identity=26.1780104712042, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=50.2673796791444, Blast_Score=202, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=33.8095238095238, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20258; Mature: 20258

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNYDSFTYNLVQYIGELGAEVAVYRNDELTVEQALALEPEKIVISPGPGTPADAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCEEEEECCCCCCCCCC
ISIPLINVVKGNIPLFGVCLGHQAIGEALGGKVVRAGQIMHGKTSQIYHDGKGVFRGLPN
CEEEEEEEEECCCCEEEEEECHHHHHHHHCCCEEECCEEECCCCCCEEECCCHHCCCCCC
PFTATRYHSLVVERESLPAELEITAWTEDGVIMGLQSSELGLYGVQFHPESIMTSVGHDL
CCCHHHHHEEEEECCCCCCEEEEEEEECCCEEEEECCCCCEEEEEEECHHHHHHHHHHHH
IRNFLEL
HHHHHCC
>Mature Secondary Structure
MILVIDNYDSFTYNLVQYIGELGAEVAVYRNDELTVEQALALEPEKIVISPGPGTPADAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCEEEEECCCCCCCCCC
ISIPLINVVKGNIPLFGVCLGHQAIGEALGGKVVRAGQIMHGKTSQIYHDGKGVFRGLPN
CEEEEEEEEECCCCEEEEEECHHHHHHHHCCCEEECCEEECCCCCCEEECCCHHCCCCCC
PFTATRYHSLVVERESLPAELEITAWTEDGVIMGLQSSELGLYGVQFHPESIMTSVGHDL
CCCHHHHHEEEEECCCCCCEEEEEEEECCCEEEEECCCCCEEEEEEECHHHHHHHHHHHH
IRNFLEL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]