Click here to switch to the map view.

The map label for this gene is accD

Identifier: 21674373

GI number: 21674373

Start: 1464730

End: 1465566

Strand: Reverse

Name: accD

Synonym: CT1555

Alternate gene names: 21674373

Gene position: 1465566-1464730 (Counterclockwise)

Preceding gene: 21674377

Following gene: 21674371

Centisome position: 68.01

GC content: 58.18

Gene sequence:

>837_bases
ATGGTCTGGTTCAAACGGGCGATTCCTTCGATACGAACAAAGGACAAGCGAGATACTCCGGAAGGGCTGTGGTCGAAATG
CGATTCGTGCGGCGCTGCGCTGCACAAGAAACAGCTTGAAGATCACCTCTATACCTGTCCGCATTGCGGTTTTCATTTCC
GCATATCGCCAGACCTTTATTTTTCCTTTCTGTTCGATGACGGGAAGTGGGAGGAGTTCGACGCGCAGCTCAGGGCTGCC
GATCCGCTCAAGTTCGTCGATACCAAGCCTTACCCTGAGCGCGTTCGCTCCACGATGCAGAAATCGGGCAAAAGCGAGGC
ATGCCGGAACGCTACCGGCAAGCTCGGTGGCTCCGACGCGGTTATTTCGGGCATGGATTTCGGCTTCATCGGCGGCTCAA
TGGGTTCAGTGGTCGGTGAGAAGATCGCCCGCGCCGCCGACAAGAGCGTGGAGCTGAACGCGCCGCTCATCGTGATTTCG
CAGTCTGGCGGCGCGCGCATGATGGAGGGGGCCTTTAGTCTTATGCAGATGGCCAAGACCTCGGCGCGGCTGACGCGCCT
CGGCGAGCGCGGTATTCCGTTCATCTCGCTCATGACCGATCCGACGATGGGCGGCATCAGCGCTTCTTTCGCCATGCTCG
GAGACCTGAACATCAGCGAGCCGAAAGCGCTTATTGGCTTTGCCGGGCCGCGCGTCATCCGCGATACCATCAAACGCGAT
CTCCCCGAAGGCTTCCAGCGAGCCGAGTTTCTGCAGAAGCACGGTTTCGTTGACACTATCGTTCACCGCAAGGATTTGCG
CGCGCAGCTCATCAAGCTGCTTGGGCATATGAAGTAA

Upstream 100 bases:

>100_bases
GCGGTTCACAAGGGACTCCGGGCACAGCCTGTTTTTTGGGAAATCGTGTCGAGTTTATATCTTGAATTTCAATGTAAAAT
CTTTAGAGATAATAATAAAA

Downstream 100 bases:

>100_bases
GGGGAAAACAGAGATACTTTCCAGGTCGAATTGGAGGGAAAAAGGGAAAAGAATTTCTTTTCCCTTTTTTCATTCAACAT
CCGTACTTCCACCCTAGCGC

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MVWFKRAIPSIRTKDKRDTPEGLWSKCDSCGAALHKKQLEDHLYTCPHCGFHFRISPDLYFSFLFDDGKWEEFDAQLRAA
DPLKFVDTKPYPERVRSTMQKSGKSEACRNATGKLGGSDAVISGMDFGFIGGSMGSVVGEKIARAADKSVELNAPLIVIS
QSGGARMMEGAFSLMQMAKTSARLTRLGERGIPFISLMTDPTMGGISASFAMLGDLNISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLQKHGFVDTIVHRKDLRAQLIKLLGHMK

Sequences:

>Translated_278_residues
MVWFKRAIPSIRTKDKRDTPEGLWSKCDSCGAALHKKQLEDHLYTCPHCGFHFRISPDLYFSFLFDDGKWEEFDAQLRAA
DPLKFVDTKPYPERVRSTMQKSGKSEACRNATGKLGGSDAVISGMDFGFIGGSMGSVVGEKIARAADKSVELNAPLIVIS
QSGGARMMEGAFSLMQMAKTSARLTRLGERGIPFISLMTDPTMGGISASFAMLGDLNISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLQKHGFVDTIVHRKDLRAQLIKLLGHMK
>Mature_278_residues
MVWFKRAIPSIRTKDKRDTPEGLWSKCDSCGAALHKKQLEDHLYTCPHCGFHFRISPDLYFSFLFDDGKWEEFDAQLRAA
DPLKFVDTKPYPERVRSTMQKSGKSEACRNATGKLGGSDAVISGMDFGFIGGSMGSVVGEKIARAADKSVELNAPLIVIS
QSGGARMMEGAFSLMQMAKTSARLTRLGERGIPFISLMTDPTMGGISASFAMLGDLNISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLQKHGFVDTIVHRKDLRAQLIKLLGHMK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=49.8194945848375, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_CHLTE (Q8KC71)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662438.1
- ProteinModelPortal:   Q8KC71
- SMR:   Q8KC71
- GeneID:   1006079
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1555
- NMPDR:   fig|194439.1.peg.1532
- TIGR:   CT1555
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK637819
- BioCyc:   CTEP194439:CT_1555-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 30720; Mature: 30720

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWFKRAIPSIRTKDKRDTPEGLWSKCDSCGAALHKKQLEDHLYTCPHCGFHFRISPDLY
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
FSFLFDDGKWEEFDAQLRAADPLKFVDTKPYPERVRSTMQKSGKSEACRNATGKLGGSDA
EEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
VISGMDFGFIGGSMGSVVGEKIARAADKSVELNAPLIVISQSGGARMMEGAFSLMQMAKT
EECCCCCHHHCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHH
SARLTRLGERGIPFISLMTDPTMGGISASFAMLGDLNISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLQKHGFVDTIVHRKDLRAQLIKLLGHMK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVWFKRAIPSIRTKDKRDTPEGLWSKCDSCGAALHKKQLEDHLYTCPHCGFHFRISPDLY
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEE
FSFLFDDGKWEEFDAQLRAADPLKFVDTKPYPERVRSTMQKSGKSEACRNATGKLGGSDA
EEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
VISGMDFGFIGGSMGSVVGEKIARAADKSVELNAPLIVISQSGGARMMEGAFSLMQMAKT
EECCCCCHHHCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHH
SARLTRLGERGIPFISLMTDPTMGGISASFAMLGDLNISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLQKHGFVDTIVHRKDLRAQLIKLLGHMK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901