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The map label for this gene is ahpF [C]

Identifier: 21674332

GI number: 21674332

Start: 1418760

End: 1419842

Strand: Reverse

Name: ahpF [C]

Synonym: CT1512

Alternate gene names: 21674332

Gene position: 1419842-1418760 (Counterclockwise)

Preceding gene: 21674333

Following gene: 21674331

Centisome position: 65.89

GC content: 58.63

Gene sequence:

>1083_bases
ATGTTAGATATTCACAATCCAGCGACCGACCACCACGATATGAGGGATCTCACCATCATCGGCGGTGGTCCAACAGGCAT
CTTCGCAGCTTTCCAGTGCGGCATGAACAACATCTCCTGCCGTATCATTGAGAGCATGCCACAGCTCGGCGGGCAGCTTG
CGGCGCTCTATCCTGAAAAACATATCTACGACGTGGCCGGCTTTCCGGAAGTTCCGGCCATCGATCTGGTCGAGAGTCTC
TGGGCGCAGGCCGAACGGTACAATCCCGATGTTGTGCTGAACGAGACGGTCACGAAATACACCAAACTCGACGACGGCAC
CTTCGAAACCCGAACCAACACGGGTAACGTTTATCGCTCACGCGCCGTGCTTATTGCTGCCGGTCTCGGTGCGTTCGAGC
CGCGCAAGCTGCCGCAGCTCGGCAACATCGACCACCTTACCGGAAGCTCGGTTTACTACGCGGTTAAATCTGTCGAGGAT
TTCAAGGGCAAGCGCGTAGTAATCGTGGGTGGCGGCGATTCGGCGCTCGACTGGACGGTGGGACTGATAAAGAACGCCGC
TTCAGTGACGCTGGTGCACCGCGGCCACGAGTTTCAGGGTCATGGCAAGACCGCGCACGAGGTGGAGCGGGCCAGGGCGA
ACGGCACGATCGACGTGTATCTCGAAACTGAAGTGGCGAGCATCGAGGAGTCAAATGGCGTGTTGACGCGCGTGCACTTG
CGCTCTAGTGATGGTTCGAAGTGGACGGTCGAGGCTGACCGGCTGCTGATTCTGATCGGCTTCAAATCGAATCTCGGTCC
GCTGGCCCGGTGGGACCTCGAACTGTACGAGAACGCGCTGGTGGTTGATTCCCATATGAAAACATCGGTCGATGGCCTCT
ACGCGGCGGGCGACATCGCGTACTACCCCGGCAAGCTCAAGATCATCCAGACCGGCCTGAGCGAGGCCACGATGGCCGTG
CGCCACAGCCTCTCCTACATCAAGCCGGGCGAGAAAATTCGTAATGTCTTCAGCAGCGTCAAGATGGCCAAGGAGAAGAA
GGCCGCCGAGGCGGGCAACGCGACGGAGAACAAGGCAGAGTAA

Upstream 100 bases:

>100_bases
TGTCGCCATTCTCTATGGCATGGTTGATCCGGAGGGCATGATCTACCTGAAAAAGTCTGACAGCTAAAGCGTCAGGGCAA
ACCCCATCAAGGCATTCATA

Downstream 100 bases:

>100_bases
GTGTATGTCCGTTTCAAGTTCATCACAGCTGTCGGCGTTTCAGGCATGGATGCTGGCTATCCGCCCGAAAACGCTTCCAG
CGGGAGCAATGCCTGTCGTG

Product: thioredoxin reductase, putative

Products: NA

Alternate protein names: FNR; Fd-NADP+ reductase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLDIHNPATDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYDVAGFPEVPAIDLVESL
WAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRSRAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVED
FKGKRVVIVGGGDSALDWTVGLIKNAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHL
RSSDGSKWTVEADRLLILIGFKSNLGPLARWDLELYENALVVDSHMKTSVDGLYAAGDIAYYPGKLKIIQTGLSEATMAV
RHSLSYIKPGEKIRNVFSSVKMAKEKKAAEAGNATENKAE

Sequences:

>Translated_360_residues
MLDIHNPATDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYDVAGFPEVPAIDLVESL
WAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRSRAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVED
FKGKRVVIVGGGDSALDWTVGLIKNAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHL
RSSDGSKWTVEADRLLILIGFKSNLGPLARWDLELYENALVVDSHMKTSVDGLYAAGDIAYYPGKLKIIQTGLSEATMAV
RHSLSYIKPGEKIRNVFSSVKMAKEKKAAEAGNATENKAE
>Mature_360_residues
MLDIHNPATDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYDVAGFPEVPAIDLVESL
WAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRSRAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVED
FKGKRVVIVGGGDSALDWTVGLIKNAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHL
RSSDGSKWTVEADRLLILIGFKSNLGPLARWDLELYENALVVDSHMKTSVDGLYAAGDIAYYPGKLKIIQTGLSEATMAV
RHSLSYIKPGEKIRNVFSSVKMAKEKKAAEAGNATENKAE

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family

Homologues:

Organism=Escherichia coli, GI87081763, Length=272, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FENR_CHLTE (Q8KCB2)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662397.1
- ProteinModelPortal:   Q8KCB2
- SMR:   Q8KCB2
- GeneID:   1006048
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1512
- NMPDR:   fig|194439.1.peg.1491
- TIGR:   CT1512
- HOGENOM:   HBG669726
- OMA:   LEYTTSS
- ProtClustDB:   CLSK637801
- BioCyc:   CTEP194439:CT_1512-MONOMER
- HAMAP:   MF_01685
- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103
- PRINTS:   PR00368
- PRINTS:   PR00469

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 39240; Mature: 39240

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: BINDING 25-25 BINDING 44-44 BINDING 52-52 BINDING 57-57 BINDING 97-97 BINDING 132-132 BINDING 298-298 BINDING 339-339

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIHNPATDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEK
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEHHHHHCCCCEEEECCCC
HIYDVAGFPEVPAIDLVESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRS
CEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHEECCCCCEEEECCCCCEEEC
RAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVEDFKGKRVVIVGGGDSALDWTV
EEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHCCCCEEEEEECCCCCHHHHH
GLIKNAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHL
HHHCCCCEEEEEECCCEECCCCCCHHHHHHHHCCCEEEEEEECEEEEECCCCCEEEEEEE
RSSDGSKWTVEADRLLILIGFKSNLGPLARWDLELYENALVVDSHMKTSVDGLYAAGDIA
ECCCCCEEEEECCEEEEEEECCCCCCCHHEEEHHHHCCEEEEECCCHHCCCCEEECCCEE
YYPGKLKIIQTGLSEATMAVRHSLSYIKPGEKIRNVFSSVKMAKEKKAAEAGNATENKAE
ECCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLDIHNPATDHHDMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEK
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEHHHHHCCCCEEEECCCC
HIYDVAGFPEVPAIDLVESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRS
CEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHEECCCCCEEEECCCCCEEEC
RAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVEDFKGKRVVIVGGGDSALDWTV
EEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHCCCCEEEEEECCCCCHHHHH
GLIKNAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHL
HHHCCCCEEEEEECCCEECCCCCCHHHHHHHHCCCEEEEEEECEEEEECCCCCEEEEEEE
RSSDGSKWTVEADRLLILIGFKSNLGPLARWDLELYENALVVDSHMKTSVDGLYAAGDIA
ECCCCCEEEEECCEEEEEEECCCCCCCHHEEEHHHHCCEEEEECCCHHCCCCEEECCCEE
YYPGKLKIIQTGLSEATMAVRHSLSYIKPGEKIRNVFSSVKMAKEKKAAEAGNATENKAE
ECCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901