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The map label for this gene is hflX [H]

Identifier: 21674206

GI number: 21674206

Start: 1298423

End: 1299748

Strand: Reverse

Name: hflX [H]

Synonym: CT1384

Alternate gene names: 21674206

Gene position: 1299748-1298423 (Counterclockwise)

Preceding gene: 21674210

Following gene: 21674205

Centisome position: 60.31

GC content: 58.37

Gene sequence:

>1326_bases
TTGACGACCATTCCATCACCGGAACCCCGGGAGCGTGCCGTACTTGTTGGCATCACTTCCACGCCTGACATTCCCAGACA
CCTTGTCGAAGAGTATCTCGACGAGCTGAAGTTTCTTGCCGATACGGCAGGAGCCGACGTTATCACCTCGATCATCCAGG
AAAAGAAACAGCCCGATCCTGCCACCTGCATCGGCAGCGGCAAGGCCGAGGATCTGGCCGGGCTGGTTGAGGCCGATTCG
ATCGATATTGTCATTTTCGATGACGACCTTACCCCCGTGCAGGTGAGGAACCTCGAACGCATTCTCAAGTGCAAGGTGAT
CGACCGCACCGGCCTCATTTTGCAAATCTTCGCCATCCGCGCCAAGTCCGCGCAGGCTCGTACGCAGGTGGAGCTGGCGC
AGCTCGAATATCTTCTGCCGCGTCTCTCCGGCGCCTGGACGCACCTTTCCAAGCAGAAGGGCGGTATTGGCACTAAAGGA
CCCGGCGAAACGCAGATCGAGACCGACCGGCGACTGGTGCGCAACCGCATCGCCTCGCTCAAAAAGAAGCTTCGCGCCGT
CTCGCTCCAGCACGACACCCAGACCCGTGGCCGGGCGGCTGTGCCGCGCGTGGCGCTGGTGGGCTACACCAACGCGGGCA
AATCGACCCTGATGAACGCGCTTTGCCCCGAAGCTGGCGCCTATGCCGAAAACCGGCTTTTCGCAACGCTCGACACCAAG
ACCCGGCGGCTTGAACTCAAAATCAACAAGCTGGTGCTGCTCTCCGATACGGTCGGCTTCATCCGCAAGCTGCCGCACAC
GCTGGTCGAGAGCTTCAAATCCACGCTTGACGAGGTGTTGCAGGCGGACTTCCTTCTGCATGTCATCGACGTGAGCCATC
CGGGTTTTGAGGAGCATATGCAGGTGGTGCGCGAGACGCTTAAAGAGATTGGCGTCAAGCACGACCACATCATCGAGGTG
TTCAACAAGATCGACGCCCTCGACGATCCTGCAATTCTGACCGGCCTGCGCGGCAAGTATCCCGACGCGGTGTTTATCTC
CGCGGTGCGCGGCTTGAATCTTTCGGCGTTGAAGGAAACTATTGCCAATTACGTCGCCCGCGACTACAAGACGCGCAAGG
TGAAAACGCACGTTTCGAACTACAAGCTGATCGGCTACCTCTACGACCACGCCGAGGTGATCGACAAGAAGCACGTTGAT
GAAGATGTGCTGCTCACCATTCGCGTGCACCGCAACAACCTCAAGCAGATCGACGCCATGCTCAAGGCGTCGGCATCGAA
AAACCATGCCGCTGCAAATCTTCAACACCACGAAACGCACGATTGA

Upstream 100 bases:

>100_bases
AAATAAAATAATGGCTCTAATATAGCAATAGCAAGGAGGTTCGCCGTTATCTGCCGATCACGGAGCGCTGTTGCATCAGA
ATCTATCCCAGACGATCCAT

Downstream 100 bases:

>100_bases
CGAAACACTCCTCGCCGAAGTCATCCGGCTGGTAATTGGCGAAGAGGGCGGTGCGGTCGGCTCCATCGAGGCGATCTACT
GCGGCAACAAGATGATCCGC

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTTIPSPEPRERAVLVGITSTPDIPRHLVEEYLDELKFLADTAGADVITSIIQEKKQPDPATCIGSGKAEDLAGLVEADS
IDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFAIRAKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKG
PGETQIETDRRLVRNRIASLKKKLRAVSLQHDTQTRGRAAVPRVALVGYTNAGKSTLMNALCPEAGAYAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPGFEEHMQVVRETLKEIGVKHDHIIEV
FNKIDALDDPAILTGLRGKYPDAVFISAVRGLNLSALKETIANYVARDYKTRKVKTHVSNYKLIGYLYDHAEVIDKKHVD
EDVLLTIRVHRNNLKQIDAMLKASASKNHAAANLQHHETHD

Sequences:

>Translated_441_residues
MTTIPSPEPRERAVLVGITSTPDIPRHLVEEYLDELKFLADTAGADVITSIIQEKKQPDPATCIGSGKAEDLAGLVEADS
IDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFAIRAKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKG
PGETQIETDRRLVRNRIASLKKKLRAVSLQHDTQTRGRAAVPRVALVGYTNAGKSTLMNALCPEAGAYAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPGFEEHMQVVRETLKEIGVKHDHIIEV
FNKIDALDDPAILTGLRGKYPDAVFISAVRGLNLSALKETIANYVARDYKTRKVKTHVSNYKLIGYLYDHAEVIDKKHVD
EDVLLTIRVHRNNLKQIDAMLKASASKNHAAANLQHHETHD
>Mature_440_residues
TTIPSPEPRERAVLVGITSTPDIPRHLVEEYLDELKFLADTAGADVITSIIQEKKQPDPATCIGSGKAEDLAGLVEADSI
DIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFAIRAKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKGP
GETQIETDRRLVRNRIASLKKKLRAVSLQHDTQTRGRAAVPRVALVGYTNAGKSTLMNALCPEAGAYAENRLFATLDTKT
RRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPGFEEHMQVVRETLKEIGVKHDHIIEVF
NKIDALDDPAILTGLRGKYPDAVFISAVRGLNLSALKETIANYVARDYKTRKVKTHVSNYKLIGYLYDHAEVIDKKHVDE
DVLLTIRVHRNNLKQIDAMLKASASKNHAAANLQHHETHD

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=271, Percent_Identity=33.210332103321, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI310133116, Length=275, Percent_Identity=33.4545454545455, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI310124269, Length=263, Percent_Identity=33.8403041825095, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310124267, Length=263, Percent_Identity=33.8403041825095, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310124171, Length=263, Percent_Identity=33.8403041825095, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310124169, Length=263, Percent_Identity=33.8403041825095, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI1790615, Length=403, Percent_Identity=43.424317617866, Blast_Score=295, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17561038, Length=325, Percent_Identity=29.8461538461538, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24650079, Length=353, Percent_Identity=31.1614730878187, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49111; Mature: 48980

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIPSPEPRERAVLVGITSTPDIPRHLVEEYLDELKFLADTAGADVITSIIQEKKQPDP
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
ATCIGSGKAEDLAGLVEADSIDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFAIR
CCEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKGPGETQIETDRRLVRNRIASL
HCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKKLRAVSLQHDTQTRGRAAVPRVALVGYTNAGKSTLMNALCPEAGAYAENRLFATLDTK
HHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCC
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPGFEEHM
CEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
QVVRETLKEIGVKHDHIIEVFNKIDALDDPAILTGLRGKYPDAVFISAVRGLNLSALKET
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCHHHHHHH
IANYVARDYKTRKVKTHVSNYKLIGYLYDHAEVIDKKHVDEDVLLTIRVHRNNLKQIDAM
HHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
LKASASKNHAAANLQHHETHD
HHHCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
TTIPSPEPRERAVLVGITSTPDIPRHLVEEYLDELKFLADTAGADVITSIIQEKKQPDP
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
ATCIGSGKAEDLAGLVEADSIDIVIFDDDLTPVQVRNLERILKCKVIDRTGLILQIFAIR
CCEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AKSAQARTQVELAQLEYLLPRLSGAWTHLSKQKGGIGTKGPGETQIETDRRLVRNRIASL
HCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKKLRAVSLQHDTQTRGRAAVPRVALVGYTNAGKSTLMNALCPEAGAYAENRLFATLDTK
HHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCC
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDVSHPGFEEHM
CEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
QVVRETLKEIGVKHDHIIEVFNKIDALDDPAILTGLRGKYPDAVFISAVRGLNLSALKET
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHCCCHHHHHHH
IANYVARDYKTRKVKTHVSNYKLIGYLYDHAEVIDKKHVDEDVLLTIRVHRNNLKQIDAM
HHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
LKASASKNHAAANLQHHETHD
HHHCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]