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The map label for this gene is zraS [C]

Identifier: 21674198

GI number: 21674198

Start: 1292621

End: 1293634

Strand: Reverse

Name: zraS [C]

Synonym: CT1376

Alternate gene names: 21674198

Gene position: 1293634-1292621 (Counterclockwise)

Preceding gene: 21674200

Following gene: 21674196

Centisome position: 60.03

GC content: 54.54

Gene sequence:

>1014_bases
ATGCTTTCAAACAGTTTCCCTGAGACCGACAAACGCCACAAGCGCATCGAGGTCATTCATCATGCGGCGCTCAGGGCGCG
CGGTCTTGTTCAGCAGCTCCTGGCCTTCAGCAGCCGCCAGACGCTTGAATTCAGAATGCTTGACCTCAACCGGGTTGTCA
GGGATTTCGAGCAGTTGCTCCGCAGAACCATCCGGGACGATATCAATATTCGGTATCATCTGCATGACGGGAGGCTGGTC
ATTCAAGGAGATGTTGGCCAGATCAAACAGATTATCATGAATCTTGCGGTCAACGCCGAGGATGCGATGCCATCGGGTGG
AGAATTAACCGTGAAGACTTCAACGATGGTGATCGGCAAGGGGCAGGAGAAATATTTCGAAGGGTTGCCCAGCGGAGACT
ATGCTGTTTTGACCGTTTGCGATACGGGCACGGGGATCGATCAGGAGACGCTTGCCTGCAAAGGGCGGGGGACTGGTCTC
GGTCTTTCGACGGTTTATGGTATTGTCAGGCAGCATGGAGGCATCATTCAGGCGGGGAGTGAGGCTGGTTCTGGAGCCTC
GTTCAGGGTATGCTTCCCTCTCCGGGAGAGCGAACCTGAGCCGCTTCAGCCGGTTAAGCCAAAGCCGCATCAGAAAGGCG
AGGGGGCAAAAGTGCTGGTTGTCGAGGATGACGAGATTGTTCGCAAATTCGTCGTTCAGGCTTTAGACGAAGAGGGATTC
GAAACCCGTGAGGCGGAGAACGGACAAGCGGCGCTGGAGCTGCTTGAAAAAGGCGATTTCAAGCCCGAGCTGTTACTGAC
TGATCTGGTCATGCGCGGCATGAACGGGCGGATGCTCTATGAAAAGGTGTGTGACTTCATGCCTGGCATCAAGGTGATCT
ACATGTCGGGGTACCCCAAGGACATCATTTCCCGGCACGGCGTACTCGATACGGGGCTGTCATTTCTGCTGAAGCCGTTT
CCGGTTCCGGTGCTTCTGGATAAGGTGAAAGACGTGCTAAAAAACGGAGAATGA

Upstream 100 bases:

>100_bases
GCTTTTTCAGTCCCAGAAGATCCAATCGATCGGCCGCTTGGCGGGCGGCATCGCCCATGACCTGAACAATCTTCTGACGC
CAGTGCTCGGTTATTCCGAG

Downstream 100 bases:

>100_bases
TGCGGGAGCCGGGCGGGAAAAGAAAAGCCGAAACCGAAGCTGTAAGCCGAATTCTGTCCATCACCATCAAGTAGTGATGT
TGCAGCCATTTATCTGATGC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLSNSFPETDKRHKRIEVIHHAALRARGLVQQLLAFSSRQTLEFRMLDLNRVVRDFEQLLRRTIRDDINIRYHLHDGRLV
IQGDVGQIKQIIMNLAVNAEDAMPSGGELTVKTSTMVIGKGQEKYFEGLPSGDYAVLTVCDTGTGIDQETLACKGRGTGL
GLSTVYGIVRQHGGIIQAGSEAGSGASFRVCFPLRESEPEPLQPVKPKPHQKGEGAKVLVVEDDEIVRKFVVQALDEEGF
ETREAENGQAALELLEKGDFKPELLLTDLVMRGMNGRMLYEKVCDFMPGIKVIYMSGYPKDIISRHGVLDTGLSFLLKPF
PVPVLLDKVKDVLKNGE

Sequences:

>Translated_337_residues
MLSNSFPETDKRHKRIEVIHHAALRARGLVQQLLAFSSRQTLEFRMLDLNRVVRDFEQLLRRTIRDDINIRYHLHDGRLV
IQGDVGQIKQIIMNLAVNAEDAMPSGGELTVKTSTMVIGKGQEKYFEGLPSGDYAVLTVCDTGTGIDQETLACKGRGTGL
GLSTVYGIVRQHGGIIQAGSEAGSGASFRVCFPLRESEPEPLQPVKPKPHQKGEGAKVLVVEDDEIVRKFVVQALDEEGF
ETREAENGQAALELLEKGDFKPELLLTDLVMRGMNGRMLYEKVCDFMPGIKVIYMSGYPKDIISRHGVLDTGLSFLLKPF
PVPVLLDKVKDVLKNGE
>Mature_337_residues
MLSNSFPETDKRHKRIEVIHHAALRARGLVQQLLAFSSRQTLEFRMLDLNRVVRDFEQLLRRTIRDDINIRYHLHDGRLV
IQGDVGQIKQIIMNLAVNAEDAMPSGGELTVKTSTMVIGKGQEKYFEGLPSGDYAVLTVCDTGTGIDQETLACKGRGTGL
GLSTVYGIVRQHGGIIQAGSEAGSGASFRVCFPLRESEPEPLQPVKPKPHQKGEGAKVLVVEDDEIVRKFVVQALDEEGF
ETREAENGQAALELLEKGDFKPELLLTDLVMRGMNGRMLYEKVCDFMPGIKVIYMSGYPKDIISRHGVLDTGLSFLLKPF
PVPVLLDKVKDVLKNGE

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=204, Percent_Identity=28.921568627451, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37385; Mature: 37385

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNSFPETDKRHKRIEVIHHAALRARGLVQQLLAFSSRQTLEFRMLDLNRVVRDFEQLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
RRTIRDDINIRYHLHDGRLVIQGDVGQIKQIIMNLAVNAEDAMPSGGELTVKTSTMVIGK
HHHHHCCCEEEEEEECCEEEEECCHHHHHHHHHHHHCCCHHCCCCCCEEEEEEEEEEEEC
GQEKYFEGLPSGDYAVLTVCDTGTGIDQETLACKGRGTGLGLSTVYGIVRQHGGIIQAGS
CHHHHHCCCCCCCEEEEEEECCCCCCCHHHEEECCCCCCCCHHHHHHHHHHCCCEEEECC
EAGSGASFRVCFPLRESEPEPLQPVKPKPHQKGEGAKVLVVEDDEIVRKFVVQALDEEGF
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCC
ETREAENGQAALELLEKGDFKPELLLTDLVMRGMNGRMLYEKVCDFMPGIKVIYMSGYPK
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCH
DIISRHGVLDTGLSFLLKPFPVPVLLDKVKDVLKNGE
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSNSFPETDKRHKRIEVIHHAALRARGLVQQLLAFSSRQTLEFRMLDLNRVVRDFEQLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
RRTIRDDINIRYHLHDGRLVIQGDVGQIKQIIMNLAVNAEDAMPSGGELTVKTSTMVIGK
HHHHHCCCEEEEEEECCEEEEECCHHHHHHHHHHHHCCCHHCCCCCCEEEEEEEEEEEEC
GQEKYFEGLPSGDYAVLTVCDTGTGIDQETLACKGRGTGLGLSTVYGIVRQHGGIIQAGS
CHHHHHCCCCCCCEEEEEEECCCCCCCHHHEEECCCCCCCCHHHHHHHHHHCCCEEEECC
EAGSGASFRVCFPLRESEPEPLQPVKPKPHQKGEGAKVLVVEDDEIVRKFVVQALDEEGF
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCC
ETREAENGQAALELLEKGDFKPELLLTDLVMRGMNGRMLYEKVCDFMPGIKVIYMSGYPK
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCH
DIISRHGVLDTGLSFLLKPFPVPVLLDKVKDVLKNGE
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA