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The map label for this gene is tolC [C]

Identifier: 21674169

GI number: 21674169

Start: 1265128

End: 1266549

Strand: Direct

Name: tolC [C]

Synonym: CT1347

Alternate gene names: 21674169

Gene position: 1265128-1266549 (Clockwise)

Preceding gene: 21674168

Following gene: 21674170

Centisome position: 58.71

GC content: 58.79

Gene sequence:

>1422_bases
ATGGTGAAAAAAAGCGTTTTCATTGGTATTCTTCTCCTCATCCTGCCAGCCCTGACCATCCACGCAGAAAGTCAGCCGGC
GAGAACCCTTTCACTGCACGAGTGCATCACGATTGCGCTCAACAACGCCTCCGACGTTAAAAAAGCTGAAAACGCCCGGC
ATCTTAGCGGTGTCGATCTTCTGAGAAGGTATGGCAACTTCCTGCCAAAAGTCACCTCCTCGGCCAGTTATGTACCCCGT
TCGGTCAACCGCTCATACACATCATACTCACCGCTGTACGGCGCCGGGTCGGACACAGCGATCAACATGACCTCCCGCAC
TTCGACCGTCGATATGAGCCTGACGGCATCGCTCAACCTCTTCAACGGCCTGAGCGACTACGCAGCCCTGCAAGCGGCGC
TCGACCGCAAAAAGGCCGCGGGGTTCACGCTTCAGCGCGCAAAAGAGACCATCGCTTACGACGTGACACAGCACTACTAT
CAGGTGCTGCTGGACAAGGAACTGCTCGATATCGCGCGGGAAAATCTCAAGACATCGCGCGATTTGCTGACCCTGACCGA
GCGGCAGTTCAACATCGGCCTCAAGTCCATCACCGACCTCTACCAGCAGCAGGCGGAAGCGAGCAACAGCAACCTCGCCG
TCATCAACGCCGAAAACCAGCTCCGTCGAAGCAAGCTCGAACTCGTCCGGCGCCTGCGCATCGATCCGGCTGAAGAGATC
GCGCTCGAACCGGTGGACACCGCGGCAATCGAAAAGCTCTCGCCCGAGGTGGACATTGCGGCGCTTTCGGCAGCAAGCCT
CCAGCAGCGGGCTGACCTCAAGGCGCAGGGCCTCGAACGCGACGCAGCGCGGCAGGATGTCCGGCAGGTTGCAGGCTCGC
GGCTGCCAAGGCTTGACCTCGCCTTCACCATGAGCAGTGGCGCGATCGACTCCTACAAAACCACCATGCTGGGCCAGACC
TACGACTACGCCTATCCGTCCGTCAGCAAGCAGCTCAAAAACGGCATCGACCACGCCGTTTCGCTTAACCTTTCGTGGAC
GATCTTCGACGGCTTCTCGACGCGCTACAATGTCGAGTCGGCAAAGGTGGTCAGCCGGAACAGGCAGCTCGATTACGAGG
AGCTGAAAGATGGCATCGAAATCGACCTGAAGCAGGTCGCCGGTGACTACCAGGCAGCCTTCACCCGAATCGAGTCGGCA
AAAAAGAGCCTGAAGGCTTCGGAATCGGCGGCTCAGGGCATCACTCGCAAATACGATCTCGGTGCCTCGAACTTTGTCGA
ACTCAGCTCGGCGAGGGCGGCGCTTTTCAGCGCCCGCTCGACCCTGACGCAGGCGATTTACAACCTCGCGCTGCAAAAGG
CGCTGCTCGATTACACCAGTGGCGTCGGCATCGAAGAGGTCAGCAACGCATCATCTCACTGA

Upstream 100 bases:

>100_bases
GCTCGACATGAATCTGTGTGGTTTGCCCGGCCATTGCGTATATTCATGGCCAGATGCTGCATCGATGCCGTAAAACCGAG
GTCAAACCCCAAGCCATCGA

Downstream 100 bases:

>100_bases
TTTATGGCTAACACCAAACGCTCCGGAAAACTCCGCAACATCTTCATCATCGGCGGCGCGCTCTTCGCCATCGGAGTCGC
AGCGCTCATCTGGCTGAACA

Product: outer membrane efflux protein, putative

Products: NA

Alternate protein names: Outer Membrane Transport/Efflux Protein; HlyD Family Secretion Protein; FusA/NodT Family Protein; Outer Membrane Channel Protein; RND Family Efflux Pump Inner Membrane Protein

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MVKKSVFIGILLLILPALTIHAESQPARTLSLHECITIALNNASDVKKAENARHLSGVDLLRRYGNFLPKVTSSASYVPR
SVNRSYTSYSPLYGAGSDTAINMTSRTSTVDMSLTASLNLFNGLSDYAALQAALDRKKAAGFTLQRAKETIAYDVTQHYY
QVLLDKELLDIARENLKTSRDLLTLTERQFNIGLKSITDLYQQQAEASNSNLAVINAENQLRRSKLELVRRLRIDPAEEI
ALEPVDTAAIEKLSPEVDIAALSAASLQQRADLKAQGLERDAARQDVRQVAGSRLPRLDLAFTMSSGAIDSYKTTMLGQT
YDYAYPSVSKQLKNGIDHAVSLNLSWTIFDGFSTRYNVESAKVVSRNRQLDYEELKDGIEIDLKQVAGDYQAAFTRIESA
KKSLKASESAAQGITRKYDLGASNFVELSSARAALFSARSTLTQAIYNLALQKALLDYTSGVGIEEVSNASSH

Sequences:

>Translated_473_residues
MVKKSVFIGILLLILPALTIHAESQPARTLSLHECITIALNNASDVKKAENARHLSGVDLLRRYGNFLPKVTSSASYVPR
SVNRSYTSYSPLYGAGSDTAINMTSRTSTVDMSLTASLNLFNGLSDYAALQAALDRKKAAGFTLQRAKETIAYDVTQHYY
QVLLDKELLDIARENLKTSRDLLTLTERQFNIGLKSITDLYQQQAEASNSNLAVINAENQLRRSKLELVRRLRIDPAEEI
ALEPVDTAAIEKLSPEVDIAALSAASLQQRADLKAQGLERDAARQDVRQVAGSRLPRLDLAFTMSSGAIDSYKTTMLGQT
YDYAYPSVSKQLKNGIDHAVSLNLSWTIFDGFSTRYNVESAKVVSRNRQLDYEELKDGIEIDLKQVAGDYQAAFTRIESA
KKSLKASESAAQGITRKYDLGASNFVELSSARAALFSARSTLTQAIYNLALQKALLDYTSGVGIEEVSNASSH
>Mature_473_residues
MVKKSVFIGILLLILPALTIHAESQPARTLSLHECITIALNNASDVKKAENARHLSGVDLLRRYGNFLPKVTSSASYVPR
SVNRSYTSYSPLYGAGSDTAINMTSRTSTVDMSLTASLNLFNGLSDYAALQAALDRKKAAGFTLQRAKETIAYDVTQHYY
QVLLDKELLDIARENLKTSRDLLTLTERQFNIGLKSITDLYQQQAEASNSNLAVINAENQLRRSKLELVRRLRIDPAEEI
ALEPVDTAAIEKLSPEVDIAALSAASLQQRADLKAQGLERDAARQDVRQVAGSRLPRLDLAFTMSSGAIDSYKTTMLGQT
YDYAYPSVSKQLKNGIDHAVSLNLSWTIFDGFSTRYNVESAKVVSRNRQLDYEELKDGIEIDLKQVAGDYQAAFTRIESA
KKSLKASESAAQGITRKYDLGASNFVELSSARAALFSARSTLTQAIYNLALQKALLDYTSGVGIEEVSNASSH

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082199, Length=394, Percent_Identity=24.6192893401015, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51970; Mature: 51970

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKSVFIGILLLILPALTIHAESQPARTLSLHECITIALNNASDVKKAENARHLSGVDL
CCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHEEEEEECCCHHHHHHHCCHHHHHHHH
LRRYGNFLPKVTSSASYVPRSVNRSYTSYSPLYGAGSDTAINMTSRTSTVDMSLTASLNL
HHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEHHHH
FNGLSDYAALQAALDRKKAAGFTLQRAKETIAYDVTQHYYQVLLDKELLDIARENLKTSR
HCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLTLTERQFNIGLKSITDLYQQQAEASNSNLAVINAENQLRRSKLELVRRLRIDPAEEI
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHH
ALEPVDTAAIEKLSPEVDIAALSAASLQQRADLKAQGLERDAARQDVRQVAGSRLPRLDL
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCEEE
AFTMSSGAIDSYKTTMLGQTYDYAYPSVSKQLKNGIDHAVSLNLSWTIFDGFSTRYNVES
EEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEEEECCCCEECCCH
AKVVSRNRQLDYEELKDGIEIDLKQVAGDYQAAFTRIESAKKSLKASESAAQGITRKYDL
HHHHHHCCCCCHHHHHCCHHEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
GASNFVELSSARAALFSARSTLTQAIYNLALQKALLDYTSGVGIEEVSNASSH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
>Mature Secondary Structure
MVKKSVFIGILLLILPALTIHAESQPARTLSLHECITIALNNASDVKKAENARHLSGVDL
CCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHEEEEEECCCHHHHHHHCCHHHHHHHH
LRRYGNFLPKVTSSASYVPRSVNRSYTSYSPLYGAGSDTAINMTSRTSTVDMSLTASLNL
HHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEHHHH
FNGLSDYAALQAALDRKKAAGFTLQRAKETIAYDVTQHYYQVLLDKELLDIARENLKTSR
HCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLTLTERQFNIGLKSITDLYQQQAEASNSNLAVINAENQLRRSKLELVRRLRIDPAEEI
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHH
ALEPVDTAAIEKLSPEVDIAALSAASLQQRADLKAQGLERDAARQDVRQVAGSRLPRLDL
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCEEE
AFTMSSGAIDSYKTTMLGQTYDYAYPSVSKQLKNGIDHAVSLNLSWTIFDGFSTRYNVES
EEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEEEECCCCEECCCH
AKVVSRNRQLDYEELKDGIEIDLKQVAGDYQAAFTRIESAKKSLKASESAAQGITRKYDL
HHHHHHCCCCCHHHHHCCHHEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
GASNFVELSSARAALFSARSTLTQAIYNLALQKALLDYTSGVGIEEVSNASSH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA