| Definition | Chlorobium tepidum TLS, complete genome. |
|---|---|
| Accession | NC_002932 |
| Length | 2,154,946 |
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The map label for this gene is fabG [C]
Identifier: 21674131
GI number: 21674131
Start: 1230557
End: 1231267
Strand: Direct
Name: fabG [C]
Synonym: CT1308
Alternate gene names: 21674131
Gene position: 1230557-1231267 (Clockwise)
Preceding gene: 21674130
Following gene: 21674135
Centisome position: 57.1
GC content: 63.29
Gene sequence:
>711_bases ATGACCACTTCAGATAACGGAAAGGTTCTTCTCATCACCGGCGCTTCGACCGGCATCGGGCGTTCGACCGCGATTCAGGC TGTGGAGGCGGGCTGGCGCGTCGTGGTTGCCGCGAGGTCAGCGGAGAAGCTGGCGGCGCTTGCCGCTGAACTGGGCGCGG AGCGGGCAATGGCCGTGCCGTGCGACGTGGCGGACTGGAACCAGCAGGAGGCGATGGTGCAGAAAACCATCGGGCGCTTC GGCAGGCTCGACGCGGTTTTCGCCAATGCGGGTTTTTCTAAAGGGTCGTCATTCATCGAGGGTGAACACCGGCCCGACGA GTGGCGCGACATGGTGATGACCAACGTCTTCGGTGCGGCAGCCACGGCGCGACTCACGCTGCCGGAGCTGATGAAGACCA AAGGCCATTTCCTCGTCACCGGTTCGGTGCTGGGCCGCGTGACGTCGATGCGAAACCTCTACGCTGCCACCAAATGGGCC GTCACCGGCATGGCGCAGGCAATCCGCAACGAAGTTGCAAGCCTTGGTGTGCGGGTCACGCTGGTTGAGCCGGGTATCGT CGATACACCGTTCTGGGAAGGTTTGCAGAAACCGGCAGCACCCGAACTGCTTCCGGAGGATGTCGCCCGCGCAGTGCTCT TCGCTCTCGGCCAGCCGCCGCATGTGGATGTGAGCGAAATCATCATTCGTCCGACCGGCCAGGCACACTGA
Upstream 100 bases:
>100_bases TCACGGAAACAAAACTTTTGTGGCTCCGTCTACCAGAAAATTCCCTCTTCCGTATATTTGCCCCCAGGCCAGCTTTAAAG CAAATAGGAAATTATACATC
Downstream 100 bases:
>100_bases CTGGGGTTTTGCTGCAAATAAAAGAGCCGGAAGAAGAAAAACTTCCGACTCTTTTATAACCTTCCTTTGCGAGAAACAGA TTATCCCCTGCCCCAGCGCT
Product: short chain dehydrogenase/reductase family oxidoreductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 236; Mature: 235
Protein sequence:
>236_residues MTTSDNGKVLLITGASTGIGRSTAIQAVEAGWRVVVAARSAEKLAALAAELGAERAMAVPCDVADWNQQEAMVQKTIGRF GRLDAVFANAGFSKGSSFIEGEHRPDEWRDMVMTNVFGAAATARLTLPELMKTKGHFLVTGSVLGRVTSMRNLYAATKWA VTGMAQAIRNEVASLGVRVTLVEPGIVDTPFWEGLQKPAAPELLPEDVARAVLFALGQPPHVDVSEIIIRPTGQAH
Sequences:
>Translated_236_residues MTTSDNGKVLLITGASTGIGRSTAIQAVEAGWRVVVAARSAEKLAALAAELGAERAMAVPCDVADWNQQEAMVQKTIGRF GRLDAVFANAGFSKGSSFIEGEHRPDEWRDMVMTNVFGAAATARLTLPELMKTKGHFLVTGSVLGRVTSMRNLYAATKWA VTGMAQAIRNEVASLGVRVTLVEPGIVDTPFWEGLQKPAAPELLPEDVARAVLFALGQPPHVDVSEIIIRPTGQAH >Mature_235_residues TTSDNGKVLLITGASTGIGRSTAIQAVEAGWRVVVAARSAEKLAALAAELGAERAMAVPCDVADWNQQEAMVQKTIGRFG RLDAVFANAGFSKGSSFIEGEHRPDEWRDMVMTNVFGAAATARLTLPELMKTKGHFLVTGSVLGRVTSMRNLYAATKWAV TGMAQAIRNEVASLGVRVTLVEPGIVDTPFWEGLQKPAAPELLPEDVARAVLFALGQPPHVDVSEIIIRPTGQAH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=31.7269076305221, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI59889578, Length=210, Percent_Identity=31.9047619047619, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=221, Percent_Identity=28.0542986425339, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=27.8947368421053, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI19923817, Length=238, Percent_Identity=26.0504201680672, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=27.6699029126214, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=28.7958115183246, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503817, Length=226, Percent_Identity=24.7787610619469, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI40807363, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI40548397, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI214010158, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI214010156, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI22758144, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI38348362, Length=193, Percent_Identity=28.4974093264249, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI38424085, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=220, Percent_Identity=29.5454545454545, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1787820, Length=243, Percent_Identity=29.2181069958848, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI87082100, Length=208, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787526, Length=224, Percent_Identity=29.0178571428571, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1786701, Length=228, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=30.1526717557252, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17563726, Length=234, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=194, Percent_Identity=28.3505154639175, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562990, Length=237, Percent_Identity=27.4261603375527, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562908, Length=208, Percent_Identity=28.8461538461538, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI72000259, Length=238, Percent_Identity=26.890756302521, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562906, Length=205, Percent_Identity=28.780487804878, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=26.2376237623762, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17544670, Length=198, Percent_Identity=32.8282828282828, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560150, Length=235, Percent_Identity=26.8085106382979, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193204405, Length=204, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17559104, Length=245, Percent_Identity=28.9795918367347, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17531453, Length=247, Percent_Identity=29.5546558704453, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=29.4416243654822, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560220, Length=246, Percent_Identity=28.8617886178862, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538486, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560332, Length=240, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI115534660, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17507613, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI32563809, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71997402, Length=186, Percent_Identity=30.1075268817204, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=26.063829787234, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=28.3653846153846, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI25147288, Length=223, Percent_Identity=24.6636771300448, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71994604, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17555706, Length=221, Percent_Identity=25.7918552036199, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17570069, Length=197, Percent_Identity=28.9340101522843, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=248, Percent_Identity=28.2258064516129, Blast_Score=97, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6322227, Length=207, Percent_Identity=30.9178743961353, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6324126, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6322226, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007236, Length=245, Percent_Identity=31.8367346938775, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24648944, Length=236, Percent_Identity=34.3220338983051, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI24641232, Length=246, Percent_Identity=32.1138211382114, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24663911, Length=245, Percent_Identity=33.469387755102, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI281364494, Length=246, Percent_Identity=32.520325203252, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=30.9236947791165, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=30.9236947791165, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=31.2, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI116007234, Length=248, Percent_Identity=29.0322580645161, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI28571387, Length=246, Percent_Identity=29.2682926829268, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21357041, Length=226, Percent_Identity=31.858407079646, Blast_Score=88, Evalue=4e-18, Organism=Drosophila melanogaster, GI21358495, Length=241, Percent_Identity=28.2157676348548, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI28571526, Length=233, Percent_Identity=33.0472103004292, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI24644339, Length=233, Percent_Identity=31.7596566523605, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI17737361, Length=227, Percent_Identity=29.0748898678414, Blast_Score=78, Evalue=4e-15, Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=31.0880829015544, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24639444, Length=231, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI116007238, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21355319, Length=195, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24581726, Length=212, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 25133; Mature: 25002
Theoretical pI: Translated: 6.96; Mature: 6.96
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTSDNGKVLLITGASTGIGRSTAIQAVEAGWRVVVAARSAEKLAALAAELGAERAMAVP CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCEECC CDVADWNQQEAMVQKTIGRFGRLDAVFANAGFSKGSSFIEGEHRPDEWRDMVMTNVFGAA CCCCCCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH ATARLTLPELMKTKGHFLVTGSVLGRVTSMRNLYAATKWAVTGMAQAIRNEVASLGVRVT HHHHCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE LVEPGIVDTPFWEGLQKPAAPELLPEDVARAVLFALGQPPHVDVSEIIIRPTGQAH EECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCC >Mature Secondary Structure TTSDNGKVLLITGASTGIGRSTAIQAVEAGWRVVVAARSAEKLAALAAELGAERAMAVP CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCEECC CDVADWNQQEAMVQKTIGRFGRLDAVFANAGFSKGSSFIEGEHRPDEWRDMVMTNVFGAA CCCCCCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH ATARLTLPELMKTKGHFLVTGSVLGRVTSMRNLYAATKWAVTGMAQAIRNEVASLGVRVT HHHHCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE LVEPGIVDTPFWEGLQKPAAPELLPEDVARAVLFALGQPPHVDVSEIIIRPTGQAH EECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11418146 [H]