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The map label for this gene is radA [H]

Identifier: 21674021

GI number: 21674021

Start: 1124067

End: 1125437

Strand: Direct

Name: radA [H]

Synonym: CT1195

Alternate gene names: 21674021

Gene position: 1124067-1125437 (Clockwise)

Preceding gene: 21674015

Following gene: 21674022

Centisome position: 52.16

GC content: 63.6

Gene sequence:

>1371_bases
ATGGCCAAATCCACCGTTCGTTACGTCTGCTCCGCCTGCGGGGCCGTTTCGCTGAAATACCAGGGGCGCTGCTTCGAGTG
CCAGAGCTGGGGCACACTGGTTGAAACCCACTTGGAAGAGCCGGATGCCAAAGTCCGCAAGAAGCGCCCCGCCGGCTCCA
TGCCCGAAGTGCAGAACCTCGACGACGACGCGCCATCCGGTTTTCACCGCACGCTGACCGGCATCGGTGAACTCGATCGC
GTGCTCGGCGGCGGACTGATGGAGGCTTCGGCGATTCTGGTGGGCGGCGAACCGGGCATCGGTAAATCAACGCTGATGCT
CCAGCTCGTACCGCGCCTGGCGGGCAAAAAGGTGCTCTACGTTGCGGGCGAAGAGTCGCCGAATCAGATCCGCGAACGCG
CCAGGCGTCTTTCGATCAAGGCACCAAACCTCCGCCTCGTCTCCGAAGTTGCGCTCGAACGGATTCTCGATGCCATCGCG
AATGAGCAGCCGGAGATGGTCATCGTCGATTCGATTCAGACCGTCTATTCGAGCGACTACCAGAGCTCGGCGGGCACCAT
CACCCAGATTCGCGAGTGCGCCGCCTCGCTCATCCGCGCGGCCAAGGAGCAGAACTTCATTTTGCTCATCATCGGGCACA
TCACCAAGGAGGGGTCGCTCGCCGGGCCGAAGGCGCTGGAGCACATGGTCGATACGGTCGTGCAGTTCGAGGGCGAAAAC
TACCAGCGCTACCGCATCATCCGCTCGGTCAAGAACCGCTTCGGCCCAACCAACGAAATCGGCGTTTTCAAGATGGGGGA
GGAGGGGTTAACCGAGGTCTCGAACCCATCGGAGTTTTTCATCTCCGACCGCCGGACGGACGTGCCGGGTACCGCCGTAT
TGGCTGGAATTGAGGGGTCGCGGGCACTGATGGTGGAGGTGCAGGCGCTGGTGTCGCGCACCGGCTACTCGATGCCGCAG
CGCATCAGCACGGGGTTTGACCTCAAGCGCATCGCGATCATCCTCGCCGTGCTCGAAAAGCGGTTGCAGTTCCAGACCGC
CGGACAGGATGTGTTCGTCAAGATCGCAGGCGGCCTGAAGCTGGTCGAACCGGCGGCTGACCTGGCCATCGCCGCCGCCG
TCGCCTCCGGCTTGCAGGACAAGCCATGCAACCCGACGGCCTGCTGCTGCGGCGAAATCGGCCTGTCGGGCGAGCTGCGC
GCCATCAGCGACGGCGAGCGCCGCATCCGCGAGGCGGTGCACCTCGGATTCACGTCGATCGTGCTGCCGGAGTCGAACAC
CCGCGAGCTGAAGCCGTCGCTGAAGAAGCTGCCCATCAGAATCGCCGGCTGCCGCACGCTGCACGAAGCGCTCGAAGCGA
TGGGAGTGTGA

Upstream 100 bases:

>100_bases
TGAAACAGCGACGCTTCTGCGTAAGAACACCCTATGTAATCAATCGAACCGAAACTTCCAACGCCGGAAACTCGGTGACA
AAAACGACAGAAACCGCTTC

Downstream 100 bases:

>100_bases
AGGAAAAAATGAACGCGACGGACGGCGGGTTTGGGCAACCGCGAGGGTTGCCCCTACAGATATTCTGCGTTTTGGCGAAA
TGTCTTACATTAGAGTAGAC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAKSTVRYVCSACGAVSLKYQGRCFECQSWGTLVETHLEEPDAKVRKKRPAGSMPEVQNLDDDAPSGFHRTLTGIGELDR
VLGGGLMEASAILVGGEPGIGKSTLMLQLVPRLAGKKVLYVAGEESPNQIRERARRLSIKAPNLRLVSEVALERILDAIA
NEQPEMVIVDSIQTVYSSDYQSSAGTITQIRECAASLIRAAKEQNFILLIIGHITKEGSLAGPKALEHMVDTVVQFEGEN
YQRYRIIRSVKNRFGPTNEIGVFKMGEEGLTEVSNPSEFFISDRRTDVPGTAVLAGIEGSRALMVEVQALVSRTGYSMPQ
RISTGFDLKRIAIILAVLEKRLQFQTAGQDVFVKIAGGLKLVEPAADLAIAAAVASGLQDKPCNPTACCCGEIGLSGELR
AISDGERRIREAVHLGFTSIVLPESNTRELKPSLKKLPIRIAGCRTLHEALEAMGV

Sequences:

>Translated_456_residues
MAKSTVRYVCSACGAVSLKYQGRCFECQSWGTLVETHLEEPDAKVRKKRPAGSMPEVQNLDDDAPSGFHRTLTGIGELDR
VLGGGLMEASAILVGGEPGIGKSTLMLQLVPRLAGKKVLYVAGEESPNQIRERARRLSIKAPNLRLVSEVALERILDAIA
NEQPEMVIVDSIQTVYSSDYQSSAGTITQIRECAASLIRAAKEQNFILLIIGHITKEGSLAGPKALEHMVDTVVQFEGEN
YQRYRIIRSVKNRFGPTNEIGVFKMGEEGLTEVSNPSEFFISDRRTDVPGTAVLAGIEGSRALMVEVQALVSRTGYSMPQ
RISTGFDLKRIAIILAVLEKRLQFQTAGQDVFVKIAGGLKLVEPAADLAIAAAVASGLQDKPCNPTACCCGEIGLSGELR
AISDGERRIREAVHLGFTSIVLPESNTRELKPSLKKLPIRIAGCRTLHEALEAMGV
>Mature_455_residues
AKSTVRYVCSACGAVSLKYQGRCFECQSWGTLVETHLEEPDAKVRKKRPAGSMPEVQNLDDDAPSGFHRTLTGIGELDRV
LGGGLMEASAILVGGEPGIGKSTLMLQLVPRLAGKKVLYVAGEESPNQIRERARRLSIKAPNLRLVSEVALERILDAIAN
EQPEMVIVDSIQTVYSSDYQSSAGTITQIRECAASLIRAAKEQNFILLIIGHITKEGSLAGPKALEHMVDTVVQFEGENY
QRYRIIRSVKNRFGPTNEIGVFKMGEEGLTEVSNPSEFFISDRRTDVPGTAVLAGIEGSRALMVEVQALVSRTGYSMPQR
ISTGFDLKRIAIILAVLEKRLQFQTAGQDVFVKIAGGLKLVEPAADLAIAAAVASGLQDKPCNPTACCCGEIGLSGELRA
ISDGERRIREAVHLGFTSIVLPESNTRELKPSLKKLPIRIAGCRTLHEALEAMGV

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=458, Percent_Identity=43.4497816593886, Blast_Score=376, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49371; Mature: 49239

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSTVRYVCSACGAVSLKYQGRCFECQSWGTLVETHLEEPDAKVRKKRPAGSMPEVQNL
CCCHHHHHHHHHCCCEEEEECCCEEEECCCHHHHHHHCCCCCHHHHHCCCCCCCCCCCCC
DDDAPSGFHRTLTGIGELDRVLGGGLMEASAILVGGEPGIGKSTLMLQLVPRLAGKKVLY
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEE
VAGEESPNQIRERARRLSIKAPNLRLVSEVALERILDAIANEQPEMVIVDSIQTVYSSDY
EECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHCCC
QSSAGTITQIRECAASLIRAAKEQNFILLIIGHITKEGSLAGPKALEHMVDTVVQFEGEN
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
YQRYRIIRSVKNRFGPTNEIGVFKMGEEGLTEVSNPSEFFISDRRTDVPGTAVLAGIEGS
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCCHHEEECCCCCCCCCCEEEEECCCC
RALMVEVQALVSRTGYSMPQRISTGFDLKRIAIILAVLEKRLQFQTAGQDVFVKIAGGLK
CCHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCE
LVEPAADLAIAAAVASGLQDKPCNPTACCCGEIGLSGELRAISDGERRIREAVHLGFTSI
EECHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCEE
VLPESNTRELKPSLKKLPIRIAGCRTLHEALEAMGV
EECCCCCHHHCCHHHHCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKSTVRYVCSACGAVSLKYQGRCFECQSWGTLVETHLEEPDAKVRKKRPAGSMPEVQNL
CCHHHHHHHHHCCCEEEEECCCEEEECCCHHHHHHHCCCCCHHHHHCCCCCCCCCCCCC
DDDAPSGFHRTLTGIGELDRVLGGGLMEASAILVGGEPGIGKSTLMLQLVPRLAGKKVLY
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEE
VAGEESPNQIRERARRLSIKAPNLRLVSEVALERILDAIANEQPEMVIVDSIQTVYSSDY
EECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHCCC
QSSAGTITQIRECAASLIRAAKEQNFILLIIGHITKEGSLAGPKALEHMVDTVVQFEGEN
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
YQRYRIIRSVKNRFGPTNEIGVFKMGEEGLTEVSNPSEFFISDRRTDVPGTAVLAGIEGS
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCCCHHEEECCCCCCCCCCEEEEECCCC
RALMVEVQALVSRTGYSMPQRISTGFDLKRIAIILAVLEKRLQFQTAGQDVFVKIAGGLK
CCHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCE
LVEPAADLAIAAAVASGLQDKPCNPTACCCGEIGLSGELRAISDGERRIREAVHLGFTSI
EECHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCEE
VLPESNTRELKPSLKKLPIRIAGCRTLHEALEAMGV
EECCCCCHHHCCHHHHCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]