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The map label for this gene is aroQ

Identifier: 21674016

GI number: 21674016

Start: 1119217

End: 1119663

Strand: Reverse

Name: aroQ

Synonym: CT1190

Alternate gene names: 21674016

Gene position: 1119663-1119217 (Counterclockwise)

Preceding gene: 21674017

Following gene: 21674012

Centisome position: 51.96

GC content: 59.73

Gene sequence:

>447_bases
ATGATGAGCGCAACCTCCCTTCTGGTCATGAACGGGCCGAATCTTTCACGTCTCGGAAAGCGTGAACCCGAAGTTTATGG
CAGTCTCACCCTCGACGAGATCAACCGGGGGATCGCGGTCGCGTTTCCGGAGGTGAGCTTCGAGTTTTTCCAGTCGGAGC
ACGAGGGTGCGCTTATCGAGAAGCTTTTCGAGATCGAAGGTCGCGGCGGTTTTTCGGGCGTCGTGCTCAACGCGGGGGCG
CTGACGCACTACTCGATTGCCCTGCGCGACGCCATCAGCGCCGTTACGATGCCTGTGGTCGAGGTGCACCTTTCCAACGT
GCACAAGCGGGAGGAGTTTCGTCACAAATCGGTGATTTCCGCCGTCTGCATCGGTGTGATCGCCGGTTTCGGAGTCGAGA
GCTACCACCTCGGCGTAAGGGCGCTGCTGGGGAGGGGTAACCGTTGA

Upstream 100 bases:

>100_bases
TAGTTATCGACGACAACCAGGTGCGCGAAAAGCTGGGCAAGCTAGTCGCCGACCGGGATCTGAGCCAGTATATCCTCTAA
GCCAAAAAGCCGGAGCAACC

Downstream 100 bases:

>100_bases
ACTGGGCCGGGAGATGACTGATTGGTTGGCTCAGACAGTTTTGTCTGAGTTGATAATTGCTTGAACCTTCGCCAGTTTGT
CTTTTACTTTTCCTCAATCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MMSATSLLVMNGPNLSRLGKREPEVYGSLTLDEINRGIAVAFPEVSFEFFQSEHEGALIEKLFEIEGRGGFSGVVLNAGA
LTHYSIALRDAISAVTMPVVEVHLSNVHKREEFRHKSVISAVCIGVIAGFGVESYHLGVRALLGRGNR

Sequences:

>Translated_148_residues
MMSATSLLVMNGPNLSRLGKREPEVYGSLTLDEINRGIAVAFPEVSFEFFQSEHEGALIEKLFEIEGRGGFSGVVLNAGA
LTHYSIALRDAISAVTMPVVEVHLSNVHKREEFRHKSVISAVCIGVIAGFGVESYHLGVRALLGRGNR
>Mature_148_residues
MMSATSLLVMNGPNLSRLGKREPEVYGSLTLDEINRGIAVAFPEVSFEFFQSEHEGALIEKLFEIEGRGGFSGVVLNAGA
LTHYSIALRDAISAVTMPVVEVHLSNVHKREEFRHKSVISAVCIGVIAGFGVESYHLGVRALLGRGNR

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_CHLTE (Q8KD64)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662081.1
- ProteinModelPortal:   Q8KD64
- SMR:   Q8KD64
- GeneID:   1006552
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1190
- NMPDR:   fig|194439.1.peg.1175
- TIGR:   CT1190
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BioCyc:   CTEP194439:CT_1190-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16054; Mature: 16054

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 26-26 ACT_SITE 103-103 BINDING 77-77 BINDING 83-83 BINDING 90-90 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSATSLLVMNGPNLSRLGKREPEVYGSLTLDEINRGIAVAFPEVSFEFFQSEHEGALIE
CCCCCEEEEECCCCHHHHCCCCCHHHCCEEHHHHCCCEEEEECCHHHHHHHCCCCCHHHH
KLFEIEGRGGFSGVVLNAGALTHYSIALRDAISAVTMPVVEVHLSNVHKREEFRHKSVIS
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVCIGVIAGFGVESYHLGVRALLGRGNR
HHHHHHHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMSATSLLVMNGPNLSRLGKREPEVYGSLTLDEINRGIAVAFPEVSFEFFQSEHEGALIE
CCCCCEEEEECCCCHHHHCCCCCHHHCCEEHHHHCCCEEEEECCHHHHHHHCCCCCHHHH
KLFEIEGRGGFSGVVLNAGALTHYSIALRDAISAVTMPVVEVHLSNVHKREEFRHKSVIS
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVCIGVIAGFGVESYHLGVRALLGRGNR
HHHHHHHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901