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The map label for this gene is fucO [H]

Identifier: 21673978

GI number: 21673978

Start: 1081830

End: 1082963

Strand: Reverse

Name: fucO [H]

Synonym: CT1152

Alternate gene names: 21673978

Gene position: 1082963-1081830 (Counterclockwise)

Preceding gene: 21673979

Following gene: 21673977

Centisome position: 50.25

GC content: 58.99

Gene sequence:

>1134_bases
ATGAACTTTTTTCTTTCCACCGACCTGTGTATCGGGGTCAACGAGGCCCTCTCTGTGCATGAGCATCTTCAGTCGCTCGG
CATCGCCAAACCGGGTATCATCTACGATGCAAGCCTTTCAGAAAACCTCTATTTCCAGGATGTACTGCGCAACATCAACG
CCTGCTACGCCAATGCGGTCGTCTATTGCAACGAGTTCAGGGGCGAGCCGACCTACCGGCATCTCGAAAATGTCGCGGAG
TTTTTCCGCCGAGAACTGCCCGATGGTCTGGTGGCTATCGGAGGCGGCAGCACCATCGATCTCGGCAAGGGAGTTGCGCT
TCTCCTGACCAACAACGTTCCGGCGCTTTCGCTCAAGGGCTTCCCGAAGGATGTGAGCGACCCAGTGCCGCTCGTGACCG
TGCCTTCACTGCTTGGCAGCGGTGCTGAGGTGAGCTATAACGCGGTCTTCATCGACGAGGATGAAGGACGCAAGCTCGGT
ATCAACAGCCGCAAGAACTTCCCGAAACGCTCGGTCATCGATCCGAAACTCTCGATGAGCGCTCCGATGGAGAGCGTCAT
CGCCTCGGCGATGGACAGCCTCGTGCACTGCGTGGACAGCTTTGGTTCGGTCAAGCACACCGCGCTGAGCCGCATCTTTT
CGATCGAAGGTTTCCAGCGCACCTTCTACGCATTGCAGCAGGGACAGCTCGACCGCGCCGAATCACGTCTCGACCTCGCT
CTTGGCAGCATTTGCGGCGTCACGGCGCTCATGAACTCCGGGGACGGCCCGACCAACGGTTTCGCCTACTACGTCGGCGT
GAAGCACCAGGTGCCGCACGGCCTTGCGGGTGCGATCTTCCTCAAGGAGGTGATGCGTTACAACGTCAACAAGGGATATG
ACAAATACGCGCTGCTCAATCCAGCCCGAAAAGAGGGCGCATCGGCAAGGGAGTCCGCGCTGGAACTGCTCGAACAGATG
GACGCGCTCTACTGCCAGCTCGCCATTCCGAACCTCGTACCCTACGGCTACGGCAAAGGCAACGTCGCCGAGCTGGCCAG
CAAAGCCTCGCAGGCGCTTTCGGGATCGTTCGGTGGCAACCCTGTGGAGTTTAACGAAGAGTCGGCCCGGGTGGTAATCG
ACGCGCTGACTTGA

Upstream 100 bases:

>100_bases
GAGGAGGTCGATCTCGTCGAATTTTACCTGAAGCAGAAAGGCATCGATCGTTCGTTCCTCCGATCCTGAAATCCGACAAA
CCCAACAAAATCAAGACAAT

Downstream 100 bases:

>100_bases
AAGAAAGTGGTGAAGTTGACGTAATGAATAACGTGGACACAAACAATAATTAAAAAAAATCAAACACTATGGCAGGAGCC
GAGCTGATTGGGAAAGAGGA

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: Propanediol oxidoreductase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNFFLSTDLCIGVNEALSVHEHLQSLGIAKPGIIYDASLSENLYFQDVLRNINACYANAVVYCNEFRGEPTYRHLENVAE
FFRRELPDGLVAIGGGSTIDLGKGVALLLTNNVPALSLKGFPKDVSDPVPLVTVPSLLGSGAEVSYNAVFIDEDEGRKLG
INSRKNFPKRSVIDPKLSMSAPMESVIASAMDSLVHCVDSFGSVKHTALSRIFSIEGFQRTFYALQQGQLDRAESRLDLA
LGSICGVTALMNSGDGPTNGFAYYVGVKHQVPHGLAGAIFLKEVMRYNVNKGYDKYALLNPARKEGASARESALELLEQM
DALYCQLAIPNLVPYGYGKGNVAELASKASQALSGSFGGNPVEFNEESARVVIDALT

Sequences:

>Translated_377_residues
MNFFLSTDLCIGVNEALSVHEHLQSLGIAKPGIIYDASLSENLYFQDVLRNINACYANAVVYCNEFRGEPTYRHLENVAE
FFRRELPDGLVAIGGGSTIDLGKGVALLLTNNVPALSLKGFPKDVSDPVPLVTVPSLLGSGAEVSYNAVFIDEDEGRKLG
INSRKNFPKRSVIDPKLSMSAPMESVIASAMDSLVHCVDSFGSVKHTALSRIFSIEGFQRTFYALQQGQLDRAESRLDLA
LGSICGVTALMNSGDGPTNGFAYYVGVKHQVPHGLAGAIFLKEVMRYNVNKGYDKYALLNPARKEGASARESALELLEQM
DALYCQLAIPNLVPYGYGKGNVAELASKASQALSGSFGGNPVEFNEESARVVIDALT
>Mature_377_residues
MNFFLSTDLCIGVNEALSVHEHLQSLGIAKPGIIYDASLSENLYFQDVLRNINACYANAVVYCNEFRGEPTYRHLENVAE
FFRRELPDGLVAIGGGSTIDLGKGVALLLTNNVPALSLKGFPKDVSDPVPLVTVPSLLGSGAEVSYNAVFIDEDEGRKLG
INSRKNFPKRSVIDPKLSMSAPMESVIASAMDSLVHCVDSFGSVKHTALSRIFSIEGFQRTFYALQQGQLDRAESRLDLA
LGSICGVTALMNSGDGPTNGFAYYVGVKHQVPHGLAGAIFLKEVMRYNVNKGYDKYALLNPARKEGASARESALELLEQM
DALYCQLAIPNLVPYGYGKGNVAELASKASQALSGSFGGNPVEFNEESARVVIDALT

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789163, Length=356, Percent_Identity=26.9662921348315, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082107, Length=257, Percent_Identity=24.9027237354086, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=22.3684210526316, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787493, Length=365, Percent_Identity=22.1917808219178, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17537053, Length=207, Percent_Identity=27.536231884058, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321181, Length=289, Percent_Identity=25.2595155709343, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR013460 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.77 [H]

Molecular weight: Translated: 40658; Mature: 40658

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFLSTDLCIGVNEALSVHEHLQSLGIAKPGIIYDASLSENLYFQDVLRNINACYANAV
CCEEEECCCEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHE
VYCNEFRGEPTYRHLENVAEFFRRELPDGLVAIGGGSTIDLGKGVALLLTNNVPALSLKG
EEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCEEEEEECCCCEEEECC
FPKDVSDPVPLVTVPSLLGSGAEVSYNAVFIDEDEGRKLGINSRKNFPKRSVIDPKLSMS
CCCCCCCCCCCEEHHHHHCCCCCEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCC
APMESVIASAMDSLVHCVDSFGSVKHTALSRIFSIEGFQRTFYALQQGQLDRAESRLDLA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHH
LGSICGVTALMNSGDGPTNGFAYYVGVKHQVPHGLAGAIFLKEVMRYNVNKGYDKYALLN
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECC
PARKEGASARESALELLEQMDALYCQLAIPNLVPYGYGKGNVAELASKASQALSGSFGGN
CHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PVEFNEESARVVIDALT
CCCCCCCCCEEEEEECC
>Mature Secondary Structure
MNFFLSTDLCIGVNEALSVHEHLQSLGIAKPGIIYDASLSENLYFQDVLRNINACYANAV
CCEEEECCCEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHE
VYCNEFRGEPTYRHLENVAEFFRRELPDGLVAIGGGSTIDLGKGVALLLTNNVPALSLKG
EEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCEEEEEECCCCEEEECC
FPKDVSDPVPLVTVPSLLGSGAEVSYNAVFIDEDEGRKLGINSRKNFPKRSVIDPKLSMS
CCCCCCCCCCCEEHHHHHCCCCCEEEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCC
APMESVIASAMDSLVHCVDSFGSVKHTALSRIFSIEGFQRTFYALQQGQLDRAESRLDLA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHH
LGSICGVTALMNSGDGPTNGFAYYVGVKHQVPHGLAGAIFLKEVMRYNVNKGYDKYALLN
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECC
PARKEGASARESALELLEQMDALYCQLAIPNLVPYGYGKGNVAELASKASQALSGSFGGN
CHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PVEFNEESARVVIDALT
CCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]