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The map label for this gene is kefC [C]

Identifier: 21673970

GI number: 21673970

Start: 1069066

End: 1071420

Strand: Direct

Name: kefC [C]

Synonym: CT1144

Alternate gene names: 21673970

Gene position: 1069066-1071420 (Clockwise)

Preceding gene: 21673968

Following gene: 21673971

Centisome position: 49.61

GC content: 52.4

Gene sequence:

>2355_bases
ATGAAGACTGAAGCGAGAATCCTGAAAGAGTGTCTGGCCGCAGCAGCGCCAAATTGTTTACATTCTATCCTGCCCCCTGT
GGTCAGAGACGACCAAACCAGAAGCATGAACAAGCCTATGGAATCCTATTACCATCAGTTTCTCGAGGAATTCCGGCTAC
CGTTGACCAATCCGGTGCTGGTCTTTTCGCTCGTGCTGTTCATTATCCTGCTCGCCCCGATTGTTTCCAAAAGATTCAAC
ATTCCCGGCACGGTCGGCCTGATTCTCTCTGGCGTGCTTATCGGGCCGCACAGCCTGAATCTTCTTGAAAAAAGCTCGGC
AGTCGAGCTTTTCTCGACCATTGGCCTGCTCTACATTCTCTTAATCGCCGGTCTCGAACTCGATGTCAACGATTTCAGGA
AAAACCGGTACAAAAGCGCCCTGTTCGGACTGCTGACCTTCAGCATTCCCATCGTCCTCGGCTATCCGGTCTGCCGCTAC
CTGCTGAACTATCCAATGAGCACCAGTCTTCTGACGGCCAGCATGTTCGCGACGCACACATTGGTAGCCTACCCTGTTGT
GAGCCGGATGGGAATCTCGAAAAACCGGACGGTTGCCATCACGGTAGCAGGAACGATCCTGAGCGATACTGCTGTGCTGA
TCCTCCTGGCGGTCATTATAGGCTATAGCCGGGGCGACATCAATCATGAGTTCTGGCTGCACCTCGTCATCGCGCTCACA
CTCTTTTCGGCGATCGTGTTCATCGTACTGCCCGCCATCGCCCGCTGGTTTTTCACCAAGCTCGAAAACGAAAAACACGC
CCACTACATCTTTGTTCTGGCGGCGCTTTTCTTTTCAGCTTTCCTCGCAAAAGCTGCAGGACTGGAACCAATTGTGGGAG
CTTTTGCGGCTGGCCTCGCGCTCAACCCTCTCATTCCAGGCTCTTCAGCCCTGATGAACCGCATCGAGTTCATCGGAAAC
TCGCTCTTCATACCATTCTTCCTCATAAGCGTGGGAATGCTGGTGGACCTGAGGATCATCCTGAGCAGCCCGATAGCCCT
GATCATCGCCGCCCTTTTGACCTTCGTGGCACTAGCAGGAAAATGGCTCGCGGCGCTCTCTACCCAGAAAATTTTCGGCT
ATTCCGCCGCTCACCGGCGGCTTATCTTCGGCCTGAGCAGCTCCCGCGCCGCCGCAACCATCGCCATCGCACTGGTTGGC
TACCGTGCACGCATCCTCGACCTTAACATCCTCAACGCCATCATTATCCTCATTCTCGTCACCTGCATCGTCAGTTCGCT
GGTTACGGAAAAGGCAGCCAAGGAGATCGTGCTTGAAGAGAACGACGCCGCACCTGAAAAAGAGCACGCACAGGGTGACG
CCGACGAGCAGATCCTGTTACCGATCGCAGAAAACAAGCCCTCCGAACGGGTGCTGGAGCTGGCCGTAATGATCAGGGAA
AAGCGCTCCCTCAATCCGCTGACCATCCTGACCGTCGTGCCCAATGATCATGAAGCTGAACTGAACGTGAAAAAAGCCAA
AAAAGAGCTGGCGCCAACAGTCGATTTTGCGGCCTCGTTCGACACCAGCCTCAACATCGTTGCAACTATCGACTACAATA
TCTGCAGCGGTATCAGCAGAGCAGTCAAGGAATCCCAGTCAAACCTGATTATCTTCGACTGGCCAAGTCGCCAGGGCTTC
CTCGGCCGGATGATCAACGACGCCACTGAGAGCATCGTGGAGTGTACCTGCAAAACCACCATGATCTGTCATCTCACACG
CCCCCTGGCCATACATCGGCGAATCGTGGTTATCTGCCCGCCTTTCGCCGAAAAAGAGAAAGGATTCGGGCAATGGCTGC
GCAAAATGAGTCGCCTGTCACAGGAATTAACCATTCCACTGCTTTTCCATTGCGACAGGAAAAGCCGGCTGGCCATCATC
GAAACATTGAAAACCAGCCATTCAACCTCTCCTGTTCTGTACGAAGTGTTCAAAAACTTCCGTGAATGGGAGGATATCGC
CAGTCGAAAACTTCACTTCAGGGAAGACGACATTGTCACGTTTGTCTGCGCCCGCAGGGAGTCCATCTCTTACAAACCCT
TTTTCGATCTCGTGCCTGAACAACTTGAAAAGCATGTGAAAGACATCAGCAAAATCATGATCTATCCGGAACAGTTCGAT
TCCGCCATCATCGAAGAGGAGTATGCCGACGTGGTCGCCCCGAAATCCTTCCCGTTCGGAGCATCGACCATCCGAAAAAT
AAGAGAAGAAATATCCGGGTTCATGAAAAAGAATCAGTTACAAATCAGAAAAAAAGCTCGGGGAAAAACGGCAGCAACAC
CAAAAAGATTTGGATTTTCCCGAAAAGAACCATAA

Upstream 100 bases:

>100_bases
CCAGAGATTTCCGCATGCTTTTCAATAGACAATCATGCTGTTCACAAGAGATTTTTTAACAATTTAAGCATTCAATCGCT
CATTCAGCGAATACCGGGCG

Downstream 100 bases:

>100_bases
ACTGCAAAGTTTTAAAAAACAAAGCGTTACGTTAACACCGTCAAATACCGCTTAACGCGGCGATCCACAGTGCCTATGCG
AAAAGAGCAGCAATCCCGTC

Product: Na+/H+ antiporter, putative

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MKTEARILKECLAAAAPNCLHSILPPVVRDDQTRSMNKPMESYYHQFLEEFRLPLTNPVLVFSLVLFIILLAPIVSKRFN
IPGTVGLILSGVLIGPHSLNLLEKSSAVELFSTIGLLYILLIAGLELDVNDFRKNRYKSALFGLLTFSIPIVLGYPVCRY
LLNYPMSTSLLTASMFATHTLVAYPVVSRMGISKNRTVAITVAGTILSDTAVLILLAVIIGYSRGDINHEFWLHLVIALT
LFSAIVFIVLPAIARWFFTKLENEKHAHYIFVLAALFFSAFLAKAAGLEPIVGAFAAGLALNPLIPGSSALMNRIEFIGN
SLFIPFFLISVGMLVDLRIILSSPIALIIAALLTFVALAGKWLAALSTQKIFGYSAAHRRLIFGLSSSRAAATIAIALVG
YRARILDLNILNAIIILILVTCIVSSLVTEKAAKEIVLEENDAAPEKEHAQGDADEQILLPIAENKPSERVLELAVMIRE
KRSLNPLTILTVVPNDHEAELNVKKAKKELAPTVDFAASFDTSLNIVATIDYNICSGISRAVKESQSNLIIFDWPSRQGF
LGRMINDATESIVECTCKTTMICHLTRPLAIHRRIVVICPPFAEKEKGFGQWLRKMSRLSQELTIPLLFHCDRKSRLAII
ETLKTSHSTSPVLYEVFKNFREWEDIASRKLHFREDDIVTFVCARRESISYKPFFDLVPEQLEKHVKDISKIMIYPEQFD
SAIIEEEYADVVAPKSFPFGASTIRKIREEISGFMKKNQLQIRKKARGKTAATPKRFGFSRKEP

Sequences:

>Translated_784_residues
MKTEARILKECLAAAAPNCLHSILPPVVRDDQTRSMNKPMESYYHQFLEEFRLPLTNPVLVFSLVLFIILLAPIVSKRFN
IPGTVGLILSGVLIGPHSLNLLEKSSAVELFSTIGLLYILLIAGLELDVNDFRKNRYKSALFGLLTFSIPIVLGYPVCRY
LLNYPMSTSLLTASMFATHTLVAYPVVSRMGISKNRTVAITVAGTILSDTAVLILLAVIIGYSRGDINHEFWLHLVIALT
LFSAIVFIVLPAIARWFFTKLENEKHAHYIFVLAALFFSAFLAKAAGLEPIVGAFAAGLALNPLIPGSSALMNRIEFIGN
SLFIPFFLISVGMLVDLRIILSSPIALIIAALLTFVALAGKWLAALSTQKIFGYSAAHRRLIFGLSSSRAAATIAIALVG
YRARILDLNILNAIIILILVTCIVSSLVTEKAAKEIVLEENDAAPEKEHAQGDADEQILLPIAENKPSERVLELAVMIRE
KRSLNPLTILTVVPNDHEAELNVKKAKKELAPTVDFAASFDTSLNIVATIDYNICSGISRAVKESQSNLIIFDWPSRQGF
LGRMINDATESIVECTCKTTMICHLTRPLAIHRRIVVICPPFAEKEKGFGQWLRKMSRLSQELTIPLLFHCDRKSRLAII
ETLKTSHSTSPVLYEVFKNFREWEDIASRKLHFREDDIVTFVCARRESISYKPFFDLVPEQLEKHVKDISKIMIYPEQFD
SAIIEEEYADVVAPKSFPFGASTIRKIREEISGFMKKNQLQIRKKARGKTAATPKRFGFSRKEP
>Mature_784_residues
MKTEARILKECLAAAAPNCLHSILPPVVRDDQTRSMNKPMESYYHQFLEEFRLPLTNPVLVFSLVLFIILLAPIVSKRFN
IPGTVGLILSGVLIGPHSLNLLEKSSAVELFSTIGLLYILLIAGLELDVNDFRKNRYKSALFGLLTFSIPIVLGYPVCRY
LLNYPMSTSLLTASMFATHTLVAYPVVSRMGISKNRTVAITVAGTILSDTAVLILLAVIIGYSRGDINHEFWLHLVIALT
LFSAIVFIVLPAIARWFFTKLENEKHAHYIFVLAALFFSAFLAKAAGLEPIVGAFAAGLALNPLIPGSSALMNRIEFIGN
SLFIPFFLISVGMLVDLRIILSSPIALIIAALLTFVALAGKWLAALSTQKIFGYSAAHRRLIFGLSSSRAAATIAIALVG
YRARILDLNILNAIIILILVTCIVSSLVTEKAAKEIVLEENDAAPEKEHAQGDADEQILLPIAENKPSERVLELAVMIRE
KRSLNPLTILTVVPNDHEAELNVKKAKKELAPTVDFAASFDTSLNIVATIDYNICSGISRAVKESQSNLIIFDWPSRQGF
LGRMINDATESIVECTCKTTMICHLTRPLAIHRRIVVICPPFAEKEKGFGQWLRKMSRLSQELTIPLLFHCDRKSRLAII
ETLKTSHSTSPVLYEVFKNFREWEDIASRKLHFREDDIVTFVCARRESISYKPFFDLVPEQLEKHVKDISKIMIYPEQFD
SAIIEEEYADVVAPKSFPFGASTIRKIREEISGFMKKNQLQIRKKARGKTAATPKRFGFSRKEP

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=476, Percent_Identity=23.7394957983193, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 87357; Mature: 87357

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEARILKECLAAAAPNCLHSILPPVVRDDQTRSMNKPMESYYHQFLEEFRLPLTNPVL
CCCHHHHHHHHHHHHCCHHHHHHCCCHHCCCCHHHCCCHHHHHHHHHHHHHCCCCCCHHH
VFSLVLFIILLAPIVSKRFNIPGTVGLILSGVLIGPHSLNLLEKSSAVELFSTIGLLYIL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIAGLELDVNDFRKNRYKSALFGLLTFSIPIVLGYPVCRYLLNYPMSTSLLTASMFATHT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LVAYPVVSRMGISKNRTVAITVAGTILSDTAVLILLAVIIGYSRGDINHEFWLHLVIALT
HHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LFSAIVFIVLPAIARWFFTKLENEKHAHYIFVLAALFFSAFLAKAAGLEPIVGAFAAGLA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LNPLIPGSSALMNRIEFIGNSLFIPFFLISVGMLVDLRIILSSPIALIIAALLTFVALAG
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KWLAALSTQKIFGYSAAHRRLIFGLSSSRAAATIAIALVGYRARILDLNILNAIIILILV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TCIVSSLVTEKAAKEIVLEENDAAPEKEHAQGDADEQILLPIAENKPSERVLELAVMIRE
HHHHHHHHHHHHHHHHEECCCCCCCCHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
KRSLNPLTILTVVPNDHEAELNVKKAKKELAPTVDFAASFDTSLNIVATIDYNICSGISR
HCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEEEEEECHHHHHHHHH
AVKESQSNLIIFDWPSRQGFLGRMINDATESIVECTCKTTMICHLTRPLAIHRRIVVICP
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEEEC
PFAEKEKGFGQWLRKMSRLSQELTIPLLFHCDRKSRLAIIETLKTSHSTSPVLYEVFKNF
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
REWEDIASRKLHFREDDIVTFVCARRESISYKPFFDLVPEQLEKHVKDISKIMIYPEQFD
HHHHHHHHHCCCCCCCCHHEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEECHHHHH
SAIIEEEYADVVAPKSFPFGASTIRKIREEISGFMKKNQLQIRKKARGKTAATPKRFGFS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC
RKEP
CCCC
>Mature Secondary Structure
MKTEARILKECLAAAAPNCLHSILPPVVRDDQTRSMNKPMESYYHQFLEEFRLPLTNPVL
CCCHHHHHHHHHHHHCCHHHHHHCCCHHCCCCHHHCCCHHHHHHHHHHHHHCCCCCCHHH
VFSLVLFIILLAPIVSKRFNIPGTVGLILSGVLIGPHSLNLLEKSSAVELFSTIGLLYIL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIAGLELDVNDFRKNRYKSALFGLLTFSIPIVLGYPVCRYLLNYPMSTSLLTASMFATHT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LVAYPVVSRMGISKNRTVAITVAGTILSDTAVLILLAVIIGYSRGDINHEFWLHLVIALT
HHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LFSAIVFIVLPAIARWFFTKLENEKHAHYIFVLAALFFSAFLAKAAGLEPIVGAFAAGLA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LNPLIPGSSALMNRIEFIGNSLFIPFFLISVGMLVDLRIILSSPIALIIAALLTFVALAG
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KWLAALSTQKIFGYSAAHRRLIFGLSSSRAAATIAIALVGYRARILDLNILNAIIILILV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TCIVSSLVTEKAAKEIVLEENDAAPEKEHAQGDADEQILLPIAENKPSERVLELAVMIRE
HHHHHHHHHHHHHHHHEECCCCCCCCHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
KRSLNPLTILTVVPNDHEAELNVKKAKKELAPTVDFAASFDTSLNIVATIDYNICSGISR
HCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEEEEEECHHHHHHHHH
AVKESQSNLIIFDWPSRQGFLGRMINDATESIVECTCKTTMICHLTRPLAIHRRIVVICP
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEEEC
PFAEKEKGFGQWLRKMSRLSQELTIPLLFHCDRKSRLAIIETLKTSHSTSPVLYEVFKNF
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
REWEDIASRKLHFREDDIVTFVCARRESISYKPFFDLVPEQLEKHVKDISKIMIYPEQFD
HHHHHHHHHCCCCCCCCHHEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEECHHHHH
SAIIEEEYADVVAPKSFPFGASTIRKIREEISGFMKKNQLQIRKKARGKTAATPKRFGFS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC
RKEP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]