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The map label for this gene is gra-orf5 [H]

Identifier: 21673969

GI number: 21673969

Start: 1068145

End: 1068981

Strand: Reverse

Name: gra-orf5 [H]

Synonym: CT1143

Alternate gene names: 21673969

Gene position: 1068981-1068145 (Counterclockwise)

Preceding gene: 21673973

Following gene: 21673967

Centisome position: 49.61

GC content: 58.66

Gene sequence:

>837_bases
ATGCGGAAATCTCTGGGCGTGGTTATTACTGGCGGGAGTGCCGGGCTCGGGCTGGCAATGGCGCGGGAGTTTTTGCGGGC
TGGTGATCGCGTCGTGATCTGCTCCCGCCGCGAATCAAATCTGAAATCGGCCTTGCAGATGCTTGGCAGTGATGTCCCGG
ACCGTAATGTTTATGGTATGGTCTGCGATGTATCGCTTCCCGCTCAGGCCGCAGACTTTGCTGCTTTTGCTGCCGCAAAA
CTCGGAATCATCGACCGTTGGATCAACAATGCAGGTACGGCGGGGCGGAAGCGCCGACCGCTCTGGGAACTTGATCTCTC
CGACATCGACGAGACCTGCCGCACCAATCTTTCCGGTAGCATGATGCTTTGCGCTGAAGCGCTGCGCGTTATGCTTCGCC
AGCCAGCGAGTGCTGACGAGCCGCTTTATCATCTGTTCAACATGGGATTTTCATCGGCGGGCCTCCGTTCATCGCCTACC
TCCGTGCCGCATCGGGCATCCAAACGGGCGGTGGCGATCATGAGCAAACTGCTTCGCCAGGAGCTCGAAGCCGCAGGTAT
CCGTTCAGTCGGTATTCACGAGCTGAGTCCCGGACTGGTGCTGACCGATCTGTTGCTCCGCGACGCTACGCCTGCTCAGA
AGCGCTTTTTCAACGCGATGGCCGAAACTTCGGAAACCGTTGCGGCAACGCTGGTGCCAGCAATCAGGGCCATCACCGGA
CGAGGCAGCACGTTGCGCTACCAGCCGGTGCTTTTCATGTTTGCAAAGCTGGCGGCGTCGGCGTTTGGTTATCGCAAGGA
GCGCTTTTTTGACAGCGAAGGGAAACCCTGGGGATAG

Upstream 100 bases:

>100_bases
TCGCTTCAGTCTTCATCGCCCGGTATTCGCTGAATGAGCGATTGAATGCTTAAATTGTTAAAAAATCTCTTGTGAACAGC
ATGATTGTCTATTGAAAAGC

Downstream 100 bases:

>100_bases
GTCTTGTAGAACTTATCGGTCGAAGCGGAAAGAGTGAAGGGCGGAAACCCGGATTCGCCCTTGAAATTCAAAATCCTCCT
TACGCCGCAATCCACTGCAC

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MRKSLGVVITGGSAGLGLAMAREFLRAGDRVVICSRRESNLKSALQMLGSDVPDRNVYGMVCDVSLPAQAADFAAFAAAK
LGIIDRWINNAGTAGRKRRPLWELDLSDIDETCRTNLSGSMMLCAEALRVMLRQPASADEPLYHLFNMGFSSAGLRSSPT
SVPHRASKRAVAIMSKLLRQELEAAGIRSVGIHELSPGLVLTDLLLRDATPAQKRFFNAMAETSETVAATLVPAIRAITG
RGSTLRYQPVLFMFAKLAASAFGYRKERFFDSEGKPWG

Sequences:

>Translated_278_residues
MRKSLGVVITGGSAGLGLAMAREFLRAGDRVVICSRRESNLKSALQMLGSDVPDRNVYGMVCDVSLPAQAADFAAFAAAK
LGIIDRWINNAGTAGRKRRPLWELDLSDIDETCRTNLSGSMMLCAEALRVMLRQPASADEPLYHLFNMGFSSAGLRSSPT
SVPHRASKRAVAIMSKLLRQELEAAGIRSVGIHELSPGLVLTDLLLRDATPAQKRFFNAMAETSETVAATLVPAIRAITG
RGSTLRYQPVLFMFAKLAASAFGYRKERFFDSEGKPWG
>Mature_278_residues
MRKSLGVVITGGSAGLGLAMAREFLRAGDRVVICSRRESNLKSALQMLGSDVPDRNVYGMVCDVSLPAQAADFAAFAAAK
LGIIDRWINNAGTAGRKRRPLWELDLSDIDETCRTNLSGSMMLCAEALRVMLRQPASADEPLYHLFNMGFSSAGLRSSPT
SVPHRASKRAVAIMSKLLRQELEAAGIRSVGIHELSPGLVLTDLLLRDATPAQKRFFNAMAETSETVAATLVPAIRAITG
RGSTLRYQPVLFMFAKLAASAFGYRKERFFDSEGKPWG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=261, Percent_Identity=27.2030651340996, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=227, Percent_Identity=27.3127753303965, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=28.8702928870293, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=28.2828282828283, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007236, Length=208, Percent_Identity=28.3653846153846, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30153; Mature: 30153

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSLGVVITGGSAGLGLAMAREFLRAGDRVVICSRRESNLKSALQMLGSDVPDRNVYGM
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCEEE
VCDVSLPAQAADFAAFAAAKLGIIDRWINNAGTAGRKRRPLWELDLSDIDETCRTNLSGS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHCCCCCH
MMLCAEALRVMLRQPASADEPLYHLFNMGFSSAGLRSSPTSVPHRASKRAVAIMSKLLRQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ELEAAGIRSVGIHELSPGLVLTDLLLRDATPAQKRFFNAMAETSETVAATLVPAIRAITG
HHHHCCCCCCCCHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGSTLRYQPVLFMFAKLAASAFGYRKERFFDSEGKPWG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRKSLGVVITGGSAGLGLAMAREFLRAGDRVVICSRRESNLKSALQMLGSDVPDRNVYGM
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCEEE
VCDVSLPAQAADFAAFAAAKLGIIDRWINNAGTAGRKRRPLWELDLSDIDETCRTNLSGS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHCCCCCH
MMLCAEALRVMLRQPASADEPLYHLFNMGFSSAGLRSSPTSVPHRASKRAVAIMSKLLRQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ELEAAGIRSVGIHELSPGLVLTDLLLRDATPAQKRFFNAMAETSETVAATLVPAIRAITG
HHHHCCCCCCCCHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGSTLRYQPVLFMFAKLAASAFGYRKERFFDSEGKPWG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 7476861; 9831526 [H]