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The map label for this gene is resA [H]

Identifier: 21673850

GI number: 21673850

Start: 963853

End: 964410

Strand: Direct

Name: resA [H]

Synonym: CT1023

Alternate gene names: 21673850

Gene position: 963853-964410 (Clockwise)

Preceding gene: 21673849

Following gene: 21673851

Centisome position: 44.73

GC content: 55.2

Gene sequence:

>558_bases
ATGAAATCCATAAAGACATTTTTCGCCACATCTTTCATGGCGCTTTCGATGCTTGGCGCGGTTCCTGTTGCAAGGACCTT
TGCAGCGGGACCTTCCGCAAGTCCCGCGGTCGCGGGCAAAATGGCACCGGCGTTCACACTCAAGACGCTCGAAGGCAAAG
AGCTGAACAGCTCGCAGCTTGCCGGGAGGCCCTATATAGTCAATTTTTTCGCCTCGTGGTGCCCACCCTGCCGTGAGGAG
CTGCCCGGCATGGTGGCATTGCAGAAAAAGTATGCCAAGCAGGGCTTTACCTTTGTTGGCATCGCTTTTCGGGATCGTCC
GGCGACCTTGCCTGATTTTCTCTGGGAGATGGGCGTCGAGTATCCGGTTGGCCTGACCACTCCCGAACTCGAAGCAGCAT
TCGGCAAGTTTATGCCTGGCGGCAAAATCCGGGTGATTCCGGCAACCTTTGTCGTCGGTCGCGATGGCAAGCTGATCAAT
GCTGTCAGTGGAGGTCTCGTCAAAGAGGATTTCGAGTCGCTCATCCTCAAAGCGATCGGCAGCAGACCTTCAAAATAA

Upstream 100 bases:

>100_bases
GCAAGCAACAGATTTTTGCTGTTGAGTACCTTGTTTTCTTTCTGAAAGAGCCTGTTGGCGGACTTCTTTTGTTTTGAAAA
GCTCAATCCATGAATGGTTT

Downstream 100 bases:

>100_bases
TTTTTGAGACGGCTCTTTGCTGATTTGTCCCTCCGAAAACCGCCCCAATGCCTTTTTTACTTTCTGGACCGGCACCCCGC
TGACCGGTTCAGAGAATCTC

Product: thioredoxin family thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKSIKTFFATSFMALSMLGAVPVARTFAAGPSASPAVAGKMAPAFTLKTLEGKELNSSQLAGRPYIVNFFASWCPPCREE
LPGMVALQKKYAKQGFTFVGIAFRDRPATLPDFLWEMGVEYPVGLTTPELEAAFGKFMPGGKIRVIPATFVVGRDGKLIN
AVSGGLVKEDFESLILKAIGSRPSK

Sequences:

>Translated_185_residues
MKSIKTFFATSFMALSMLGAVPVARTFAAGPSASPAVAGKMAPAFTLKTLEGKELNSSQLAGRPYIVNFFASWCPPCREE
LPGMVALQKKYAKQGFTFVGIAFRDRPATLPDFLWEMGVEYPVGLTTPELEAAFGKFMPGGKIRVIPATFVVGRDGKLIN
AVSGGLVKEDFESLILKAIGSRPSK
>Mature_185_residues
MKSIKTFFATSFMALSMLGAVPVARTFAAGPSASPAVAGKMAPAFTLKTLEGKELNSSQLAGRPYIVNFFASWCPPCREE
LPGMVALQKKYAKQGFTFVGIAFRDRPATLPDFLWEMGVEYPVGLTTPELEAAFGKFMPGGKIRVIPATFVVGRDGKLIN
AVSGGLVKEDFESLILKAIGSRPSK

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19843; Mature: 19843

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIKTFFATSFMALSMLGAVPVARTFAAGPSASPAVAGKMAPAFTLKTLEGKELNSSQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEEECCCCCCCCHHC
AGRPYIVNFFASWCPPCREELPGMVALQKKYAKQGFTFVGIAFRDRPATLPDFLWEMGVE
CCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCC
YPVGLTTPELEAAFGKFMPGGKIRVIPATFVVGRDGKLINAVSGGLVKEDFESLILKAIG
CCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEHHHHCCHHHHHHHHHHHHHHC
SRPSK
CCCCC
>Mature Secondary Structure
MKSIKTFFATSFMALSMLGAVPVARTFAAGPSASPAVAGKMAPAFTLKTLEGKELNSSQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEEECCCCCCCCHHC
AGRPYIVNFFASWCPPCREELPGMVALQKKYAKQGFTFVGIAFRDRPATLPDFLWEMGVE
CCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCC
YPVGLTTPELEAAFGKFMPGGKIRVIPATFVVGRDGKLINAVSGGLVKEDFESLILKAIG
CCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEHHHHCCHHHHHHHHHHHHHHC
SRPSK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]